KEGG T00306: SDY

Shigella dysenteriae: SDY_0002

Entry

SDY_0002 CDS T00306

Gene name

thrA

Definition

bifunctional aspartokinase I/homoserine dehydrogenase I (EC:1.1.1.13 2.7.2.4)

Orthology

K12524

bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]

Organism

sdy Shigella dysenteriae

Pathway

sdy00260	Glycine, serine and threonine metabolism
sdy00270	Cysteine and methionine metabolism
sdy00300	Lysine biosynthesis
sdy01100	Metabolic pathways
sdy01110	Biosynthesis of secondary metabolites
sdy01120	Microbial metabolism in diverse environments
sdy01230	Biosynthesis of amino acids

Module

sdy_M00016	Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sdy_M00017	Methionine biosynthesis, apartate => homoserine => methionine
sdy_M00018	Threonine biosynthesis, aspartate => homoserine => threonine

Class

Metabolism; Amino acid metabolism; Glycine, serine and threonine metabolism [PATH:sdy00260]
Metabolism; Amino acid metabolism; Cysteine and methionine metabolism [PATH:sdy00270]
Metabolism; Amino acid metabolism; Lysine biosynthesis [PATH:sdy00300]

SSDB

Motif

Pfam:

Homoserine_dh AA_kinase NAD_binding_3 ACT_7 ACT

Other DBs

NCBI-GI:

NCBI-GeneID:

ShiBASE_China:

UniProt:

Position

336..2798

AA seq 820 aa
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA
LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRMP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRVDCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQSSSEYSISF
CVPQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQEELAQAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMA
NLSQLDELFAARVAKARDEGKVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV

NT seq 2463 nt +upstreamnt +downstreamnt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgggtt
gccgatattttggaaagcaatgccaggcaggggcaggtggccaccgtcctctctgccccc
gccaaaataaccaaccacctggtggcgatgattgaaaaaaccattagcggccaggatgct
ttacccaatatcagcgatgccgaacgtatttttgccgaacttctgacgggactcgccgcc
gcccagccgggattcccgctggcgcaattgaaaactttcgtcgaccaggaatttgcccaa
ataaaacatgtcctgcatggcattagtttgttagggcagtgcccggatagcattaacgct
gcgctgatttgccgtggcgagaaaatgtcgatcgccattatggccggcgtgttagaagcg
cgtggtcacaacgttaccgttatcgatccggtcgaaaaactactggcagtggggcattac
ctcgaatctaccgtcgatattgctgagtccacccgccgtattgcggcaagtcgtatgccg
gctgatcacatggtgctgatggcaggtttcaccgccggtaatgaaaaaggcgaactggtg
gtgcttggacgcaatggttccgactactccgcggcggttctggctgcctgtttacgcgtc
gattgttgcgagatttggacggacgttgacggggtctatacctgcgacccgcgtcaggtg
cccgatgcgaggttgttgaagtcgatgtcctaccaggaagcgatggagctttcctacttt
ggcgctaaagttcttcacccccgcaccattacccccatcgcccagttccagatcccttgc
ctgattaaaaataccggaaatcctcaagcaccaggtacgctcattggtgccagtcgtgat
gaagacgaattaccggtcaagggcatttccaatctgaataacatggcaatgttcagcgtt
tccggcccggggatgaaaggaatggtcggcatggcggcgcgcgtctttgctgcaatgtca
cgcgcccgtatttccgtggtgctgattacgcaatcatcttccgaatacagtatcagtttc
tgcgttccgcaaagcgactgtgtgcgagctgaacgggcaatgcaggaggagttctacctg
gaactgaaagaaggcttactggagccgctggcggtgacggaacggctggccattatctcg
gtggtaggtgatggtatgcgcaccttgcgtgggatctcggcgaaattctttgccgcgctg
gcccgcgccaatatcaacattgtcgccattgctcagggatcttctgaacgctcaatctct
gtcgtggtaaataacgatgatgcgaccactggcgtgcgcgttactcatcagatgctgttc
aatacggatcaggttatcgaagtgtttgtgattggcgtcggtggcgttggcggtgcgctg
ctggagcaactgaagcgtcaacaaagctggctgaagaataaacatattgacttacgtgtc
tgcggcgttgccaactcgaaggctctgcttaccaatgtgcatggcctaaacctggaaaac
tggcaggaagaactggctcaagccaaagagccgtttaatctcgggcgcttaattcgcctc
gtgaaagaatatcatctgctgaacccggtcattgttgactgcacctccagccaggcagtg
gcggatcaatatgccgacttcctgcgcgaaggtttccacgttgtcacgccgaataaaaag
gccaacacctcgtcgatggattactaccatcagttgcgttatgcggcggaaaaatcgcga
cgtaaattcctctatgacaccaacgttggggctggattaccggttattgagaacctgcaa
aatctgctcaatgcaggtgatgaattgatgaagttctccggcattctttcaggttcgctt
tcttatatcttcggcaagttagacgaaggcatgagtttctccgaggcgactactctggcg
cgggaaatgggttataccgaaccggatccgcgagatgatctttctggtatggatgtagcg
cgtaaactattaattctcgctcgtgaaacgggacgtgaactggagctggcggatattgaa
attgaacctgtgctgcccgcagagtttaacgccgagggtgatgttgccgcttttatggcg
aatctgtcacagctcgacgagctctttgccgcgcgcgtggcgaaggctcgtgatgaagga
aaagttttgcgctatgttggcaatattgatgaagatggtgtctgccgcgtgaagattgcc
gaagtggatggtaatgatccgctgttcaaagtgaaaaatggcgaaaacgccctggccttt
tatagccactattatcagccgctgccattggtgctgcgcggatatggtgcgggcaatgac
gttaccgctgctggtgtctttgccgatctgctgcgtaccctctcatggaagttaggagtc
tga

All links

Pathway (10)   
   KEGG PATHWAY (7)   
   KEGG MODULE (3)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
   SHIBASE_CHINA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (39)   

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