KEGG   Salmonella enterica subsp. enterica serovar Typhimurium UK-1: STMUK_0154
Entry
STMUK_0154        CDS       T01743                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
sej  Salmonella enterica subsp. enterica serovar Typhimurium UK-1
Pathway
sej00010  Glycolysis / Gluconeogenesis
sej00020  Citrate cycle (TCA cycle)
sej00620  Pyruvate metabolism
sej00785  Lipoic acid metabolism
sej01100  Metabolic pathways
sej01110  Biosynthesis of secondary metabolites
sej01120  Microbial metabolism in diverse environments
sej01200  Carbon metabolism
sej01210  2-Oxocarboxylic acid metabolism
Module
sej_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:sej00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    STMUK_0154 (aceE)
   00020 Citrate cycle (TCA cycle)
    STMUK_0154 (aceE)
   00620 Pyruvate metabolism
    STMUK_0154 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    STMUK_0154 (aceE)
Enzymes [BR:sej01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     STMUK_0154 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N Transketolase_C
Other DBs
NCBI-ProteinID: AEF06088
UniProt: A0A3Z2F6M2
Position
176243..178906
AA seq 887 aa
MSERFQNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGAGASNY
INTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDV
CFNHFFRARNEQDGGDLVYFQGHISPGIYARAFLEGRLTQEQMDNFRQEVHGNGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIVNELEGIFAGAGWNVIKVMWGGRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYITFPEGSEEHKYLHERRQALHGYLPSRQPNFTEKLELPQLS
DFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNDLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETL
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAITKFNIDADKVNPRLA
NT seq 2664 nt   +upstreamnt  +downstreamnt
atgtcagaacgtttccaaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgcgctcagtatctgattgaccaactg
ctttctgaagctcgtaaaggcggcgtgaaagtcgcggcaggcgcaggggccagtaattac
atcaacactattgccgttgaagacgaaccggaatacccgggtaatctggagctggaacgt
cgcattcgttctgcgatccgctggaacgccatcatgaccgtgctgcgcgcgtctaaaaaa
gaccttgagttgggcggccacatggcgtccttccagtcttccgccacgatctatgatgtc
tgttttaaccatttcttccgtgcgcgcaacgaacaggatggcggcgacctggtgtacttc
cagggccacatctctccgggcatctacgctcgcgcgttcctggaaggtcgtctgacccag
gaacagatggataacttccgtcaggaagttcacggcaatggcctctcttcctatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtctctatgggtctgggcccaatc
ggtgctatctaccaggcgaaattcctgaaatatctggaacaccgcggcctgaaagatacc
tctaaacaaaccgtttacgccttcctcggcgacggcgagatggatgagccggaatccaaa
ggcgcgatcaccatcgccacccgtgaaaaactggacaacctggtctttgttatcaactgt
aacctgcagcgtcttgacggcccggtcaccggtaacggcaagattgttaacgaactggaa
ggcatctttgcaggtgctggctggaacgttatcaaagtcatgtggggcggtcgttgggat
gaactgctgcgtaaagacaccagcggtaagcttatccagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcttacgtgcgtgagcacttcttcggt
aaatacccggaaaccgcagccctggtggccgactggaccgatgagcagatttgggcgctg
aaccgcggtggtcacgatccgaagaaagtctatgctgcactgaaaaaagcgcaggaaacc
aaaggcaaagcgaccgtaatcctggcccataccattaaaggttacggcatgggcgacacc
gcggaaggcaaaaacatcgctcaccaggtgaagaaaatgaacatggacggcgtgcgttac
gtccgcgatcgtttcaacgtgccggttgccgatgctgatctcgaaaaactgccgtacatt
accttcccggaaggttctgaagaacacaaatacctgcatgaacgccgtcaggcgctgcat
ggctacctgccaagccgtcagccgaacttcaccgagaagttagagctgcctcaactttca
gatttcggcgcgctgctggaagagcaaagtaaagagatttccactacgatcgctttcgtg
cgtgccctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggttccgatcatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagattggtatctacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaaggtatcaacgagctgggcgcaggcgcatcctggctg
gctgcggcgacctcttacagcaccaacgatctgccgatgatcccgttctacatctactac
tctatgttcgggttccagcgtatcggcgacctgtgctggcaggctggcgaccagcaggct
cgcggcttcctgatcggcgggacttccggtcgtactacgctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcttacgcttacgaagtggctgtcatcatgcatgatggtctggagcgtatgtacggt
gagaaacaagagaacgtttactactacatcaccacgctgaacgaaaactaccacatgccg
gccatgccagcaggtgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccctc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtgcgt
gaagcagcacagatcctggcgaaagattacggcgtaggttctgacgtatatagcgtgacc
tccttcaccgaactggcgcgtgatggtcaggattgtgaacgctggaacatgctgcacccg
ctggaaaccccgcgcgttccgtacatcgctcaggtgatgaacgacgctccggctgtagca
tctactgactatatgaaactgttcgccgagcaggttcgtacttacgtaccggctgacgac
tatcgcgtactgggtacggatggcttcggccgttccgacagccgtgagaacctgcgtcac
cacttcgaagttgatgcttcttatgtggttgttgcagcgctgggcgaactggctaaacgt
ggcgaaatcgacaagaaagtggtagcggatgcgattaccaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (36)   

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