KEGG   PATHWAY: sen00280Help
Entry
sen00280                    Pathway                                

Name
Valine, leucine and isoleucine degradation - Saccharopolyspora erythraea
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
Valine, leucine and isoleucine degradation
sen00280

All organismsOrtholog table
Other DBs
Organism
Saccharopolyspora erythraea [GN:sen]
Gene
branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] [KO:K00826] [EC:2.6.1.42]
branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] [KO:K00826] [EC:2.6.1.42]
pyruvate dehydrogenase (acetyl-transferring) beta subunit; K11381 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] [KO:K11381] [EC:1.2.4.4]
dldH2; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
lpdA; flavoprotein disulfide reductase [KO:K00382] [EC:1.8.1.4]
pdhD; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
fadE21; acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
acyl-CoA dehydrogenase; K00249 acyl-CoA dehydrogenase [EC:1.3.8.7] [KO:K00249] [EC:1.3.8.7]
acyl-CoA dehydrogenase; K00249 acyl-CoA dehydrogenase [EC:1.3.8.7] [KO:K00249] [EC:1.3.8.7]
acdA; acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
fadE22; acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
fadE31; acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
acyl-CoA dehydrogenase; K00249 acyl-CoA dehydrogenase [EC:1.3.8.7] [KO:K00249] [EC:1.3.8.7]
acyl-CoA dehydrogenase; K00249 acyl-CoA dehydrogenase [EC:1.3.8.7] [KO:K00249] [EC:1.3.8.7]
fadE1; acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
fadE13; acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
acyl-CoA dehydrogenase; K00249 acyl-CoA dehydrogenase [EC:1.3.8.7] [KO:K00249] [EC:1.3.8.7]
echA; enoyl-CoA hydratase-isomerase [KO:K01692] [EC:4.2.1.17]
enoyl-CoA hydratase/carnithine racemase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
echA5; enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
echA9; enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
fadB; 3-hydroxyacyl-CoA dehydrogenase [KO:K01782] [EC:5.1.2.3 4.2.1.17 1.1.1.35]
fadA; 3-ketoacyl-CoA thiolase [KO:K00632] [EC:2.3.1.16]
acetyl/propionyl-CoA carboxylase subunit alpha; K00632 acetyl-CoA acyltransferase [EC:2.3.1.16] [KO:K00632] [EC:2.3.1.16]
acetyl-CoA carboxylase subunit alpha; K01965 propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] [KO:K01965] [EC:6.4.1.3]
pccB; propionyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3]
acetyl-CoA carboxylase subunit epsilon; K11263 acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14] [KO:K11263] [EC:6.3.4.14 6.4.1.3 6.4.1.2]
acetyl-CoA carboxylase subunit epsilon; K11263 acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14] [KO:K11263] [EC:6.3.4.14 6.4.1.3 6.4.1.2]
acetyl/propionyl-CoA carboxylase subunit alpha; K11263 acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14] [KO:K11263] [EC:6.3.4.14 6.4.1.3 6.4.1.2]
methylmalonyl-CoA epimerase; K05606 methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] [KO:K05606] [EC:5.1.99.1]
mutB; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
mutA; methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
6-phosphogluconate dehydrogenase; K00020 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] [KO:K00020] [EC:1.1.1.31]
mmsB; 3-hydroxyisobutyrate dehydrogenase [KO:K00020] [EC:1.1.1.31]
6-phosphogluconate dehydrogenase; K00020 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] [KO:K00020] [EC:1.1.1.31]
mmsA2; methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.27 1.2.1.18]
mmsA3; methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.27 1.2.1.18]
mmsA1; methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.27 1.2.1.18]
aldA; aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
betaine-aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
aldH; aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
gabT; 4-aminobutyrate aminotransferase [KO:K07250] [EC:2.6.1.22 2.6.1.19]
accD1; propionyl-CoA carboxylase subunit beta [KO:K01969] [EC:6.4.1.4]
echA21; enoyl-CoA hydratase [KO:K13766] [EC:4.2.1.18]
hmgL; hydroxymethylglutaryl-CoA lyase [KO:K01640] [EC:4.1.3.4]
hydroxymethylglutaryl-CoA lyase; K01640 hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] [KO:K01640] [EC:4.1.3.4]
hydroxymethylglutaryl-CoA lyase; K01640 hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] [KO:K01640] [EC:4.1.3.4]
acsA; acetoacetyl-CoA synthetase [KO:K01907] [EC:6.2.1.16]
mmgA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
fadA4; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
fadA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
catF; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
fadD36; acyl-CoA synthetase [KO:K18662] [EC:6.2.1.-]
Compound
C00024  
Acetyl-CoA
C00068  
Thiamin diphosphate
C00091  
Succinyl-CoA
C00100  
Propanoyl-CoA
C00123  
L-Leucine
C00141  
3-Methyl-2-oxobutanoic acid
C00164  
Acetoacetate
C00183  
L-Valine
C00233  
4-Methyl-2-oxopentanoate
C00332  
Acetoacetyl-CoA
C00356  
(S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  
L-Isoleucine
C00630  
2-Methylpropanoyl-CoA
C00671  
(S)-3-Methyl-2-oxopentanoic acid
C00683  
(S)-Methylmalonyl-CoA
C01213  
(R)-Methylmalonyl-CoA
C02170  
Methylmalonate
C02939  
3-Methylbutanoyl-CoA
C03069  
3-Methylcrotonyl-CoA
C03231  
3-Methylglutaconyl-CoA
C03284  
L-3-Amino-isobutanoate
C03344  
2-Methylacetoacetyl-CoA
C03345  
2-Methylbut-2-enoyl-CoA
C03460  
2-Methylprop-2-enoyl-CoA
C04405  
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  
Branched chain fatty acid
C05998  
3-Hydroxyisovaleryl-CoA
C06000  
(S)-3-Hydroxyisobutyryl-CoA
C06001  
(S)-3-Hydroxyisobutyrate
C06002  
(S)-Methylmalonate semialdehyde
C15972  
Enzyme N6-(lipoyl)lysine
C15973  
Enzyme N6-(dihydrolipoyl)lysine
C15974  
3-Methyl-1-hydroxybutyl-ThPP
C15975  
[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  
2-Methyl-1-hydroxypropyl-ThPP
C15977  
[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  
2-Methyl-1-hydroxybutyl-ThPP
C15979  
[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  
(S)-2-Methylbutanoyl-CoA
C20827  
3-Hydroxyisovalerate
KO pathway
 

DBGET integrated database retrieval system