KEGG   Saccharopolyspora erythraea: SACE_6944Help
Entry
SACE_6944         CDS       T00492                                 

Gene name
hemD
Definition
uroporphyrinogen III synthase/methyltransferase (EC:2.1.1.107 4.2.1.75)
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
sen  Saccharopolyspora erythraea
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:sen00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    SACE_6944 (hemD)
Enzymes [BR:sen01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     SACE_6944 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     SACE_6944 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Cambridge: 
Kitasato: 
UniProt: 
Position
complement(7760152..7761684)
Genome map
AA seq 510 aa AA seqDB search
MTRARKTPGRIAFVGSGPGDAGLLTVRARHVITSASLVVTDPDVPADIVGLAAEGAEVRP
AVGDPADVALDLANEAKTGRPVVRLVAGDPLTADAVVREVQAVAKTDVAFDIVPGVPAGS
AVPAYAGVALGAVHAEVDVRGDVDWASLAKVPGALVLHTAGTHLAEAASALVEHGRAAQT
PVAVTASGTTVQQRTIDTTLASLAADAGELQGQLVVTIGDVVSERNSLSWWESRALYGWK
VLVPRTKEQAGSMSERLWSHGAVSHEVPTISVEPPRSPAQMERAVKGLVDGRYQWVVFTS
TNAVRAVWEKFREFGLDARAFSGVKIACVGEATAEKVRSFGINPELVPSGEQSSEGLLQD
FPPHDDILDPVDRVLLPRADIATETLAAGLRERGWEIDDVTAYRTVRAAPPPAETREMIK
TGGFDAVCFTSASTVRNLVGIAGKPHARTLVACIGPSTAETAKEFGLRVDVQPEVPQIPV
LVDALAEHAARLRAEGALPPPKKAKRARRS
NT seq 1533 nt NT seq  +upstreamnt  +downstreamnt
atgacccgagcacgtaagacccccggacggattgctttcgtgggctcaggccccggtgat
gctggactgctcaccgtccgggccaggcacgtgatcaccagcgcatcgctggtggtcacc
gatccggacgtacccgccgacatcgtcgggctggccgccgagggcgccgaggtgcgcccc
gcggtgggcgacccggccgacgtggcgctggacctggccaacgaggccaagacgggccgc
cccgtggtccggctggtcgcgggcgacccgctgaccgccgacgcggtggtgcgcgaggtg
caggcggtcgccaagaccgacgtcgccttcgacatcgttcccggcgttcccgccggctcc
gcggtgcccgcctacgcgggtgtcgcgctgggcgcggtgcacgccgaggtcgatgtccgc
ggcgacgtcgactgggcctcgctggccaaggtgccgggtgcgctggtgctgcacaccgcg
ggcacccacctggccgaggcggcctccgcgctggtcgagcacggcagggccgcgcagacc
ccggtcgcggtgaccgcgtcgggcaccacggtccagcagcgcaccatcgacaccacgctg
gcctcgctggccgccgacgccggtgagctgcaggggcagctcgtggtgaccatcggcgac
gtggtgtccgagcgcaacagcctgtcgtggtgggagtcccgcgccctgtacggctggaag
gtcctggtgccgcgcaccaaggagcaggccggttcgatgagcgagcggctctggtcgcac
ggcgccgtctcgcacgaggtcccgacgatctcggtggagccgccgcgcagccccgcgcag
atggagcgcgcggtcaagggcctggtcgacggccgttaccagtgggtggtgttcacctcg
accaacgccgtgcgcgcggtgtgggagaagttccgggagttcgggctggacgcccgcgcc
ttctccggcgtcaagatcgcctgcgtcggcgaggccaccgcggagaaggtccgctccttc
ggcatcaaccccgagctggtcccctccggggagcagtccagcgagggtctgctgcaggac
ttcccgccgcacgacgacatcctggacccggtggaccgggtgctgctgccgcgcgcggac
atcgccaccgagacgctggcggccggtctgcgcgagcgcggctgggagatcgacgacgtg
acggcctaccgcacggtgcgggcggcgccgccgccggccgagacccgggagatgatcaag
accggcgggttcgacgcggtctgcttcacctcggcctcgaccgtgcgcaacctggtcggc
atcgcgggcaagccgcacgcgcggaccctggtggcctgcatcggcccgagcacggcggag
acggccaaggagttcggcctgcgcgtcgacgtccagccggaggtcccgcagatcccggtc
ctggtcgacgccctggccgagcacgccgcccgcctccgcgccgaaggcgccctcccgccc
ccgaagaaggccaagagggcccggaggtcttga

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