KEGG   Shigella flexneri NCTC1 (serotype 2a): NCTC1_00072
Entry
NCTC1_00072       CDS       T03751                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase,2-isopropylmalate synthase,2-isopropylmalate synthase,Isopropylmalate/homocitrate/citramalate synthases,2-isopropylmalate synthase,HMGL-like
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sft  Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00290  Valine, leucine and isoleucine biosynthesis
sft00620  Pyruvate metabolism
sft01100  Metabolic pathways
sft01110  Biosynthesis of secondary metabolites
sft01210  2-Oxocarboxylic acid metabolism
sft01230  Biosynthesis of amino acids
Module
sft_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sft00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    NCTC1_00072 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NCTC1_00072 (leuA)
Enzymes [BR:sft01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     NCTC1_00072 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: CDX05368
UniProt: Q83SP0
Position
1:complement(79286..80857)
AA seq 523 aa
MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF
LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA
EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVTNYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKTQHNENNKETV
NT seq 1572 nt   +upstreamnt  +downstreamnt
atgagccagcaagtcattattttcgataccacattgcgcgacggtgaacaggcgttacag
gcaagcttgagtgtgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt
gacgtgatggaagtcggtttccccgtctcttcgccgggcgattttgaatcggtgcaaacc
atcgcccgccaggttaaaaacagccgcgtatgtgcgttagctcgctgcgtggaaaaagat
atcgacgtggcggccgaatccctgaaagtcgccgaagccttccgtattcatacctttatt
gctacctccccaatgcacatcgccaccaagctgcgcagcaccctagacgaggtgatcgaa
cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc
gaagatgccgggcgtacacccattgccgatctggcgcgagtggtcgaagcggcgattaat
gccggtgccaccaccatcaacattccggacaccgtgggctacaccatgccgtttgagttc
gccggaatcatcagcggcctgtatgaacgcgtacctaacatcgacaaagccattatttcc
gtacatacccacgacgatttaggcctggcggtcggcaactcactggcggcggtacatgcc
ggtgcacgccaggtggaaggtgcaatgaacgggatcggcgagcgtgccggtaactgttcg
ctggaagaagtcatcatggcgattaaagttcgtaaggatattctcaacgtccacaccgcc
attaatcaccaagagatatggcgcaccagccagttagttagccagatttgtaatatgccg
atcccggcaaacaaagccattgttggcagcggcgcattcgctcactcctccggtatccac
caggatggcgtgctgaaaaaccgcgaaaactacgaaatcatgacaccagaatctattggt
ctgaaccaaatccagctgaatctgacctctcgttcggggcgtgcggcggtgaaacatcgc
atggatgagatggggtataaagaaagtgaatataatttagacaatttgtacgatgctttc
ctgaagctggcggacaaaaaaggtcaggtgtttgattacgatctggaggcgctggccttc
atcggtaagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtct
ggctctaacgatatcgccaccgccgccgtcaaactggcctgtggcgaagaagtcaaagca
gaagccgccaacggtaacggtccggtcgatgccgtctatcaggcaattaaccgcatcact
gactataacgtcgaactggtgaaatacagcctgaccgccaaaggtcacggtaaagatgcg
ctgggtcaggtggatattgtcaccaactacaacggtcgccgcttccacggcgtcggcctg
gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtactgaacaatatctgg
cgtgccgcagaagtcgaaaaagagttgcaacgcaaaactcaacacaacgaaaacaacaag
gaaaccgtgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (24)   

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