KEGG   Sarcophilus harrisii (Tasmanian devil): 100913352Help
Entry
100913352         CDS       T02286                                 

Gene name
TGFBR2
Definition
(RefSeq) transforming growth factor, beta receptor II (70/80kDa)
  KO
K04388  
TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
Endocytosis
TGF-beta signaling pathway
Osteoclast differentiation
Hippo signaling pathway
Adherens junction
AGE-RAGE signaling pathway in diabetic complications
Chagas disease (American trypanosomiasis)
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
Colorectal cancer
Pancreatic cancer
Chronic myeloid leukemia
Module
TGF-beta signaling
Brite
KEGG Orthology (KO) [BR:shr00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100913352 (TGFBR2)
   04350 TGF-beta signaling pathway
    100913352 (TGFBR2)
   04390 Hippo signaling pathway
    100913352 (TGFBR2)
   04068 FoxO signaling pathway
    100913352 (TGFBR2)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100913352 (TGFBR2)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100913352 (TGFBR2)
  Cellular commiunity
   04520 Adherens junction
    100913352 (TGFBR2)
 Organismal Systems
  Development
   04380 Osteoclast differentiation
    100913352 (TGFBR2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100913352 (TGFBR2)
   05202 Transcriptional misregulation in cancers
    100913352 (TGFBR2)
   05210 Colorectal cancer
    100913352 (TGFBR2)
   05212 Pancreatic cancer
    100913352 (TGFBR2)
   05220 Chronic myeloid leukemia
    100913352 (TGFBR2)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100913352 (TGFBR2)
  Infectious diseases
   05166 HTLV-I infection
    100913352 (TGFBR2)
   05142 Chagas disease (American trypanosomiasis)
    100913352 (TGFBR2)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     100913352 (TGFBR2)
Protein kinases [BR:shr01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   100913352 (TGFBR2)
Enzyme-linked receptors [BR:shr01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   100913352 (TGFBR2)
Cytokine receptors [BR:shr04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   100913352 (TGFBR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Position
5
AA seq 501 aa AA seqDB search
MALSKEPLGVSLDGNPVTEENGALKTALLCKFCDVQATNCTSNDRNCLSFCDITSICEQA
HEICVAVWYIQTGEESNEDGQVCLQAEVFDHSELLAIISKVTIISLLPPVGIAIAVIVIF
YCYRVHRRRKLSTTWESSKSRKLVECSDRCAMMMDDDRSDISSTCANNLNHNTELLPIEL
DTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKEIFSDINLKHENILQ
FLTAEERKMDLGKQYWLITAFHARGNLQEYLTRHVISWEDLWKLGSSLSRGIAHLHSDHT
PCGRPKTAIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMA
PEVLESRMNLENMESFKQTDVYSMALVLWEMTSRCNEIGEVKEYEPPFGSKVREHPCVES
MKDNVLRDRGRPEIPNTWLSHRGIQMVCETLAECWDHDPEARLTAQCVAERFEELSDLDR
LSGRSCSEEKIPEDCSLSTPK
NT seq 1506 nt NT seq  +upstreamnt  +downstreamnt
atggcgctctcaaaggaaccattgggtgtttcacttgatggaaatccggtcactgaggaa
aatggtgcattaaagaccgcgctcctctgcaagttctgtgatgtacaagcaaccaactgc
accagcaatgacaggaactgcttaagtttctgcgacatcacttcgatctgtgaacaagcc
catgaaatctgcgtggctgtgtggtatattcaaactggagaggagagcaatgaggatggg
caggtctgtctgcaggcagaagtttttgaccactccgagcttttggccatcatctccaaa
gtgaccatcatcagcctccttccgcccgtgggcatcgctatcgccgtgattgtcatcttc
tactgctaccgggtacaccgcaggagaaagctgagtaccacctgggagagcagcaagtcg
cggaagctggtagagtgcagcgaccgctgtgccatgatgatggatgacgaccgctcggac
ataagctccacctgcgccaacaacctcaatcacaacacagagctgctgcccatcgagctg
gacaccctggtgggcaaggggcgctttgctgaggtctacaaggccaagctgaaacagaac
acttccgagcagttcgagacggtggcggtcaagatctttccctatgaggaatatgcctcc
tggaagactgaaaaggagatcttctcggacatcaacctcaagcatgagaacatccttcag
ttcctgacggcggaggagcggaagatggacttgggaaagcagtattggctcatcaccgcc
ttccatgccaggggcaacctgcaggagtacctcaccaggcacgtcatcagctgggaggac
ctgtggaagctgggcagctccctgtccaggggcatcgcccatctccatagcgaccacact
ccctgcgggagaccaaaaacagccatcgttcacagagacctgaagagctccaacatccta
gtgaaaaacgacctgacctgctgcctctgtgactttgggctgtccctgagattggacccg
accctctctgtggatgacttggccaacagcgggcaggttgggacagcaagatatatggct
cctgaggttttggaatccagaatgaacttggaaaatatggagtccttcaagcaaacagat
gtatattccatggccctggttctctgggaaatgacgtctcgctgcaatgagataggagag
gtcaaggaatatgagccgccatttggttccaaagtgagagagcatccctgcgtcgagagc
atgaaggacaacgtgctgagagaccggggtcggcctgagatccccaacacgtggctcagc
caccgaggtatacagatggtttgtgagactttggccgagtgctgggaccacgatccagaa
gcacggctgaccgcccagtgcgtggccgaacgttttgaagaactgagcgatctggatcgg
ctgtcggggagaagctgttcagaggagaagatccctgaggactgctccctgagcaccccc
aagtaa

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