KEGG T02286: 100914804

Sarcophilus harrisii (Tasmanian devil): 100914804

Entry

100914804 CDS T02286

Gene name

PAK2

Definition

p21 protein (Cdc42/Rac)-activated kinase 2

Orthology

K04410

p21-activated kinase 2 [EC:2.7.11.1]

Organism

shr Sarcophilus harrisii (Tasmanian devil)

Pathway

shr04010	MAPK signaling pathway
shr04012	ErbB signaling pathway
shr04360	Axon guidance
shr04510	Focal adhesion
shr04660	T cell receptor signaling pathway
shr04810	Regulation of actin cytoskeleton
shr05211	Renal cell carcinoma

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:shr04010]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:shr04012]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:shr04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:shr04510]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:shr04660]
Organismal Systems; Development; Axon guidance [PATH:shr04360]
Human Diseases; Cancers; Renal cell carcinoma [PATH:shr05211]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr PBD Kinase-like APH Kdo

Other DBs

NCBI-GI:

395519181

NCBI-GeneID:

100914804

Position

AA seq 524 aa
MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEERKPRNKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKSSETSAAVTEEDDDDEETAP
PVIAPRPDHTKSIYTRSVIDPIPAPAGDSNVDSAAKSLDKQKKKTKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR

NT seq 1575 nt +upstreamnt +downstreamnt
atgtctgataacggagaactggaagacaagccaccagcgcctcctgtccgtatgagcagt
actatttttagcactggaggcaaagaccctttgtcagctaaccatagtttgaaacctttg
ccatctgttccagaggaaagaaagcctaggaataagatcatctccatattttcaggcaca
gagaaaggaagtaagaaaaaagaaaaggaacggccagaaatttctcctccttctgatttt
gaacacaccatccatgttggctttgatgctgttactggagaattcactggaatgccagaa
cagtgggctcgattgctacagacttccaatatcaccaaactagagcaaaagaagaacccc
caggctgtgctggatgttctaaagttctatgactccaatacagtgaaacagaaatatttg
agctttacccctcctgagaaagatggctttccctcaggaacaccagcactaaatgcaaaa
agctcagaaacttcagcggcagtaacagaagaagatgatgatgatgaggagactgcacca
cctgtcattgctcctagaccagatcatacaaaatcaatttacacacggtctgtaattgac
cctattcctgcaccagctggtgattctaatgttgatagtgctgccaaatctttagacaaa
cagaaaaagaagactaaaatgacagatgaagaaattatggagaaactaagaactatagtc
agcataggtgatcccaagaaaaaatatacccgatatgaaaaaattgggcaaggagcttca
ggtacagtttttactgctacagatgtggcattggggcaggaggttgccatcaaacagata
aatttgcagaaacagcctaagaaggaattaatcattaatgaaattcttgtaatgaaagaa
ttaaaaaatcccaatatagtcaacttcttagatagttatcttgtaggggatgaattattt
gtggtaatggagtaccttgctggagggtctcttactgatgttgtaacagaaacctgcatg
gatgaagcacagattgctgctgtgtgtagagagtgtttacaagctctggagtttctacat
gccaatcaggtgattcacagagacatcaaaagtgacaatgtgcttttgggaatggaagga
tcagttaaactcaccgactttggtttctgtgcccagatcacaccagagcagagcaaaaga
agtactatggtggggaccccttactggatggcaccggaagtggtcacacgtaaagcttat
ggtcctaaagtggacatttggtctttaggaattatggctattgaaatggtggaaggagaa
cccccataccttaatgagaatcctctgagggccttgtatctaatagcaacaaatgggact
cctgaactgcaaaatccagagaaactatctccaatatttcgagatttcttaaatcgatgt
ttggagatggatgtagaaaaaaggggctcagccaaagaattgttacagcatcccttcctg
aaactggctaaacctttgtctagcttgacaccgctgatcatggcagctaaagaagcaatg
aagagtaaccgttaa

All links

Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (6)   
   Pfam (6)   
All databases (25)   

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