KEGG   Sarcophilus harrisii (Tasmanian devil): 100915481Help
Entry
100915481         CDS       T02286                                 

Gene name
PRKACA
Definition
protein kinase, cAMP-dependent, catalytic, alpha
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:shr00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100915481 (PRKACA)
   04010 MAPK signaling pathway
    100915481 (PRKACA)
   04310 Wnt signaling pathway
    100915481 (PRKACA)
   04340 Hedgehog signaling pathway
    100915481 (PRKACA)
   04020 Calcium signaling pathway
    100915481 (PRKACA)
   04024 cAMP signaling pathway
    100915481 (PRKACA)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    100915481 (PRKACA)
   04210 Apoptosis
    100915481 (PRKACA)
  Cellular commiunity
   04540 Gap junction
    100915481 (PRKACA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100915481 (PRKACA)
   04062 Chemokine signaling pathway
    100915481 (PRKACA)
  Endocrine system
   04911 Insulin secretion
    100915481 (PRKACA)
   04910 Insulin signaling pathway
    100915481 (PRKACA)
   04912 GnRH signaling pathway
    100915481 (PRKACA)
   04913 Ovarian Steroidogenesis
    100915481 (PRKACA)
   04915 Estrogen signaling pathway
    100915481 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    100915481 (PRKACA)
   04921 Oxytocin signaling pathway
    100915481 (PRKACA)
   04918 Thyroid hormone synthesis
    100915481 (PRKACA)
   04919 Thyroid hormone signaling pathway
    100915481 (PRKACA)
   04916 Melanogenesis
    100915481 (PRKACA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100915481 (PRKACA)
   04270 Vascular smooth muscle contraction
    100915481 (PRKACA)
  Digestive system
   04970 Salivary secretion
    100915481 (PRKACA)
   04971 Gastric acid secretion
    100915481 (PRKACA)
   04976 Bile secretion
    100915481 (PRKACA)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    100915481 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100915481 (PRKACA)
  Nervous system
   04724 Glutamatergic synapse
    100915481 (PRKACA)
   04727 GABAergic synapse
    100915481 (PRKACA)
   04725 Cholinergic synapse
    100915481 (PRKACA)
   04728 Dopaminergic synapse
    100915481 (PRKACA)
   04726 Serotonergic synapse
    100915481 (PRKACA)
   04720 Long-term potentiation
    100915481 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    100915481 (PRKACA)
  Sensory system
   04740 Olfactory transduction
    100915481 (PRKACA)
   04742 Taste transduction
    100915481 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    100915481 (PRKACA)
  Environmental adaptation
   04713 Circadian entrainment
    100915481 (PRKACA)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100915481 (PRKACA)
   05203 Viral carcinogenesis
    100915481 (PRKACA)
  Neurodegenerative diseases
   05012 Parkinson's disease
    100915481 (PRKACA)
   05020 Prion diseases
    100915481 (PRKACA)
  Substance dependence
   05030 Cocaine addiction
    100915481 (PRKACA)
   05031 Amphetamine addiction
    100915481 (PRKACA)
   05032 Morphine addiction
    100915481 (PRKACA)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    100915481 (PRKACA)
  Infectious diseases
   05166 HTLV-I infection
    100915481 (PRKACA)
   05169 Epstein-Barr virus infection
    100915481 (PRKACA)
   05146 Amoebiasis
    100915481 (PRKACA)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100915481 (PRKACA)
Protein kinases [BR:shr01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   100915481 (PRKACA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
2
AA seq 352 aa AA seqDB search
MGNAATAKKGSELESVKEFLAKAKEEFLKKWESPPQQSTVQLDQFDRIKTLGTGSFGRVI
LVKHKESGNYFAMKVLDKQKVVKLKQIEHTMNEKRILQAINFPFLVRLEYSFKDNTNLYM
VMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQG
YIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF
FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFA
TTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEELRISITEKCAKEFADF
NT seq 1059 nt NT seq  +upstreamnt  +downstreamnt
atggggaacgcggccaccgccaagaagggcagcgagctggagagcgtgaaagagtttcta
gctaaagccaaagaagaattcctcaagaaatgggaaagtccacctcagcaaagtacagtc
cagctggatcaatttgacagaatcaagactctaggcactggttcctttggtcgagtgata
cttgtgaagcacaaagaatcggggaactactttgccatgaaagtgcttgacaaacagaag
gttgtgaagctgaaacaaattgagcatacaatgaatgagaagcgtatcctgcaggccatc
aacttcccattccttgtgcgactagaatattccttcaaggacaacacaaacctgtacatg
gtgatggagtacgtcccaggtggggaaatgttttcccacctacggcggatcggaaggttc
agtgagccccatgctcgcttttatgcagctcagattgtcctgacctttgaataccttcac
tcattggacctgatctaccgggacctgaagcctgagaatcttctcattgaccagcagggc
tatatccaggtgacagattttggttttgccaagcgtgtgaaaggccgaacctggactttg
tgtgggacgcccgaatacctggctcctgagatcatccttagcaaggggtataacaaggct
gtggattggtgggccctaggtgtcctgatctatgaaatggcagcaggctatcctcctttc
tttgctgaccagcccatccagatatatgaaaagattgtgtctgggaaggtgcgattccct
tctcacttcagctccgatttaaaggacctgcttcggaatctgctccaagtggacctcacc
aaacgctatgggaacctcaaaaatggtgtcaatgacatcaagaaccacaaatggttcgcc
accactgactggatcgccatctaccagaggaaggtggaagctccctttataccaaagtgc
aaaggcccaggtgacacaagtaattttgatgattatgaggaagaagagctccggatctcc
atcactgagaagtgcgccaaggaatttgccgacttctaa

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