KEGG   Sarcophilus harrisii (Tasmanian devil): 100917022Help
Entry
100917022         CDS       T02286                                 

Gene name
PLCE1
Definition
phospholipase C, epsilon 1
Orthology
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Phosphatidylinositol signaling system
Thyroid hormone signaling pathway
Proteoglycans in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100917022 (PLCE1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100917022 (PLCE1)
   04015 Rap1 signaling pathway
    100917022 (PLCE1)
   04020 Calcium signaling pathway
    100917022 (PLCE1)
   04070 Phosphatidylinositol signaling system
    100917022 (PLCE1)
   04024 cAMP signaling pathway
    100917022 (PLCE1)
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100917022 (PLCE1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100917022 (PLCE1)
Enzymes [BR:shr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100917022 (PLCE1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 2292 aa AA seqDB search
MTSEEMVASVPMTQKKVIVASSATDESSENVSDISVMKRHTNKPNKEIPHTLSCLNRFRE
EPIENSLPNIFSVSSKEAISDKNIHENFRDRSMAESMEYININCNNMPNNCQSSYSHFCK
SCDSKSEENLCLDTGISSSLERNMFPGIKLEVDDSSGETNPIRSQSAIIQTNKGHIDNMA
IFHFHYAVQRNASKTFCTISDGLILDDCGNCVQLPNVRDDQKDNYSAYTCSLMELTNDYD
HKNGLKRCDNYDTLRDKYLCLERSCQEVKMACSNKSFCGDDFPGRMPTKPFLSHLEDCTD
NFEEDFFKNKKERSTLLIRRFCKNDKEVKKSVYTGTRAIMRTLPSGHIGPGAWSYIEQKR
SYDIKNFSSSEKTATVQIKQDVNLCLGKSHWFLINNTVRKGEETERTFGSIFHFFGKTLA
LDIIHGHINIGPCLKQCVRDTSCEYRATFQRTSISQYITGSLLEATASLGARSGLLNTFG
GSVGRTMLKERQPCTSTASSINLPSNVSGLSNELIELQHLIQFPEEVACILTEQEQNIYR
QVLPVDYLCFLTRDLGNAECQSKLPCLRATVSASILTPQNNEHSALENLVTRFNEVSSWV
TWLILTAGTMEEKREVFSYLVHIAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSDI
ETMRSLKDAMAQHESSSEYKKVVNRALNIPGCKVVPFCGVFLKELCEILDGTSGFMKLCP
RYNSQDETLEFVADYNGQDNFLQRVGQDGLNNPEKESTVNSIFQIIRSCNRSLEPEEEDS
LSEGDDSRKNSLKDKTRLQFVIGELSDSESDIFEQAKEWDFHGTEEEQKAFKHGTELIPW
YVLSIRADVHQFILQGATVIHYDQDAHLSARCFLRLQPDNSTLTWIKPTTASLANTKAKL
GITGNLADPGKLQSLGNTGLNGLMEGFLDLFSVKAVYMGHPGIDMHTVCVQNKLSNMSLL
ENSVTLLYGLQTTENRLLHFVAPKHTAKMLYNGLLELTKAVRKMKKFPDQRQQWLRKQYV
SLYQEDGRFEGPTLAHAIELFGGRRWTTRNTSPATLSKSVEKPIVQRNNTLGISANKKKK
KILMRGESGEGTDDEMATRKAKMHKECRGRSGSDPQDLNEQEESDQNVIISPCNNLPSRR
ANSLTTAGSPNLAAGATSPVRPLSSPVLSPSNKNQPNTWSSSSWHGRVKGGLKGFQNFMV
SDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCSRSGSESVPLYTNLRIDENTSGLQ
PDLDLLTRNVSDLGLFIKNRQQLSDNQRQISDAIAAASIVTNGSGIESTTLGVCGVGILQ
LNDFLVNCQGEHYTYDEILSIIQKFEPSVSMYQQGLMSFEGFSRFLMDKDNFASQNDESQ
ENVKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMP
IIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKNVFGEK
LVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQTQSNN
GGNANPMSANNEEEEEEEDEYDYDYESLSDDNILEDRPESKSASDKLQFEYNEEIPKRIK
KADSSVCNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNPSGS
NRGKERKSRKSIFGNNPGRLSPGETAAYTKTSGKSPLDGVRQTWEEVCSLSTAPSLSAII
RTPRCYHISSLNENAAKRLCRRYSRKLIQHTACQLLRTYPAATRIDSSNPNPLLFWLHGI
QLVALNYQTDDLPLHLNTAMFEANGGCGYVLKPPVLWDKNCAMYQQFSPLERDMENMEPA
LYSLTIVSGQNVCPSNSTGSPCIEIDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFRVH
FEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRRME
EHSSGSAVAASLMFSTEERKGLMTYKVTVHGIPGPEPFAIFIINKEIKAKQLLHQILTAS
QNSIPVTPDCFLMEEKYFISKEKNDFRKQPFQRIIGPEEEIVQILNSWFPEEGYVGRIIF
KIQEERPEEKNIFQEEKEVMLSSEDESFFVQVHDVSPEQPRTVIKAPRVSTAQEVIQQTL
CKAKYSYSILSNPNPSDYVLLEEVLKEPASKKSSTPKSSQRVLGDQECVFQAQSRWKGAG
KFILKLKEQVQAARDDKKKGISFANELKKFAKSSKQYRGFTSPSQLSIAESVQMKEEKSV
GSFSSETTDHHP
NT seq 6879 nt NT seq  +upstreamnt  +downstreamnt
atgacctctgaagaaatggtagcttctgttcctatgacacagaaaaaagtgatagttgct
agctcagctacagatgaaagtagtgaaaatgtctcagatatcagtgttatgaaaagacat
actaataagccaaacaaagaaatccctcatactctctcatgtttaaacagatttagagaa
gaacctattgaaaattcattgcccaatattttctcagtctcaagtaaagaagcaatcagt
gataagaatatccatgaaaactttagggatagaagcatggcagagtcaatggaatatatt
aacattaactgtaacaacatgcctaataactgccagagttcatatagccatttctgtaag
tcatgtgactctaaatcagaagaaaacctgtgtttggatactggaatttcatcttcactg
gaaagaaacatgtttcctggaattaaactagaagttgatgactcttcaggggaaacaaat
cctataagaagtcaatcagcaattattcagactaacaaaggtcatattgataatatggct
atatttcattttcattatgcagttcagagaaatgcatcaaagactttttgtaccatatct
gatggcttaattttagatgattgcggcaactgtgtacaactaccaaatgttagagatgat
caaaaagacaattactcagcatatacttgtagcttaatggaattgacaaatgattatgac
cataagaatggactgaagagatgtgataactatgataccttaagagataaatatttatgc
ttagaaagatcttgccaggaggttaaaatggcatgttcaaataaaagtttctgtggtgat
gattttcctggaagaatgcctaccaagccctttttgagtcatttggaagattgtactgat
aattttgaagaagatttttttaaaaacaaaaaggagcgatccactttgttaattagaaga
ttttgcaaaaatgataaggaagttaaaaaatctgtttatacaggaaccagagcaattatg
agaaccctgccttctgggcatataggacctggagcttggagttatattgagcagaaaaga
agttatgacattaagaattttagcagttcagagaaaacagcaacagtacagattaagcaa
gatgtgaatctctgtcttggaaaatcccattggtttctgatcaacaacactgtgagaaaa
ggagaagaaacagaacgcacttttggatcaattttccatttctttgggaagactctagcc
ttagatataatccatggacatattaatattggcccatgcttgaagcaatgtgttcgagat
acttcatgtgaataccgagctacctttcaaaggacttcaatttctcagtatatcactggt
tctctattggaagcaactgcgtctctgggtgcaagaagtggccttttaaatacttttgga
ggatcagtaggaagaacaatgttgaaagaacgtcaaccatgtacctccacagccagttca
atcaacttaccttcaaatgtatctggtttaagtaacgagctcatagaacttcaacacctc
attcagttccctgaagaagtggcttgtattctgactgaacaggagcagaatatctaccga
caagtgctacctgtcgactacctttgcttcttaaccagggacttgggaaatgctgaatgc
cagagtaaacttccatgcctcagagctacagtatctgcatctattcttaccccccagaac
aatgagcacagtgctctggaaaaccttgtaacaagatttaatgaggtgagttcttgggtg
acgtggctgatactcacagcaggtaccatggaagaaaaacgggaagtcttctcatattta
gtacacattgcaaaatgctgctggaatatgggcaactacaatgctgttatggaattcttg
gctggcctcaggtcaaggaaagttttaaagatgtggcagtttatggaccagtctgatatt
gaaaccatgagaagcctgaaggatgcaatggcccaacatgaatcttcctctgaatacaag
aaagtggtaaaccgggctctgaatatccctggctgtaaagtggttcctttctgtggtgtc
tttttaaaggagctctgtgaaattctagatggaacatctggatttatgaaactttgccca
cgatataattcacaagatgaaactttagagtttgtagctgattacaatggacaagataat
tttttacaacgagtaggacaagatggcttaaacaacccagagaaagaatccactgtcaac
agtatttttcaaattatccgaagctgcaatcgtagtctggaacctgaagaagaagacagc
ttaagtgaaggcgatgattcaaggaaaaattccttgaaagataaaacccgactacagttt
gtaattggagaactgtctgattcagaaagtgatatttttgagcaggccaaagaatgggat
ttccatggaacggaagaagagcagaaagcattcaagcatggcacagaactcattccctgg
tatgtcttgtcaattagagctgatgtccatcagttcatactccaaggagccactgttatt
cactatgaccaggatgcacatctgtcagcacgatgctttcttcgacttcaacctgataat
agtactttgacctggatcaaacctacaactgcctcactcgccaatactaaagccaaatta
ggcatcacaggaaatttagctgaccctggcaaacttcaatcacttggcaatactggatta
aatggactgatggaaggttttctggatttgttttcagtcaaggctgtgtacatgggacat
cctggcattgatatgcacactgtgtgtgttcagaacaaactcagtaacatgtccctctta
gagaatagtgtgacactgctttatggccttcaaactactgagaatagattattacacttt
gtggcaccaaaacatactgctaaaatgttgtataatggattattagaattaacaaaagct
gtaagaaaaatgaagaaatttcctgaccagcgacagcagtggctaaggaagcaatatgtc
agcctctatcaggaggatggaagatttgaaggtccaactttggctcatgctatcgaactg
tttggtggcagacgttggactacacgaaatacaagtccagcaacactttctaaaagtgtg
gagaaacccattgtgcaaaggaacaacacccttgggataagtgcaaataagaaaaagaaa
aaaatccttatgaggggtgaaagtggagagggtactgatgatgagatggccacacgaaag
gcaaaaatgcataaggaatgccgtggccgcagtggctcagatcctcaagaccttaatgag
caagaagaatcagatcagaatgttattattagtccctgtaataatctgccatccaggaga
gccaattctttgactacagctggatctcctaacttggctgctggagcaacttcaccagtc
agaccactttcctctcctgtattgtcaccttcaaataagaatcagcctaatacatggagc
agcagtagttggcatggccgagttaaaggtggactgaagggatttcaaaatttcatggtt
tcagatagtaacatgagttttgttgaatttgtagagctgttcaagtcattcagtgtacga
agtcgaaaggacctcaaggatctttttgacatctatgctgtaccctgcagtcgatcagga
tctgagtctgtcccactctatacaaacctgagaattgatgaaaataccagtggccttcag
cctgatttagatttgttaaccaggaacgtgtctgacttgggcttgttcattaagaatagg
caacagttatcagacaaccagaggcagatatctgatgccatcgcagctgctagtattgtg
actaatggttctggaatagaaagcaccacgcttggtgtctgtggggttggcatattacag
ctgaatgactttttagtgaattgccaaggggaacactacacttatgatgagatcctcagc
attatccagaaattcgagcctagtgtgagtatgtatcagcaaggtctaatgtcatttgaa
ggattttccaggtttctgatggataaagataattttgcttcccaaaatgatgaatcacag
gagaatgttaaagaattgcagttaccactctcctattattacattgaatcttcacacaac
acatacctcacaggacatcagcttaaaggagagtcctcagtggagctatatagccaggtc
ctcttgcaaggctgtcggagtgtggaattagactgttgggatggtgatgatggaatgcca
attatctatcatggacatacacttactaccaagattcccttcaaggaagtagttgaagcc
attgatcgcagtgccttcatcaactctgacttgcctattataatatctatagaaaatcac
tgttcattgcctcagcaacgaaaaatggcagaaattttcaagaatgtatttggagaaaaa
ctagttgccaaatttttgtttgagagtgatttctctgatgatccaatgcttccttcacct
gaccaacttaggagaaaagtacttcttaaaaacaaaaaactgaaggcacatcagactcca
gtggacatattaaagcaaaaggctcatcaactggcatccatgcaaacacaaagcaataat
ggtggtaatgccaatcctatgtctgccaacaatgaagaagaagaggaggaggaggatgaa
tatgattatgactatgaatctctttctgatgacaacatcctggaagaccggcctgaaagt
aagtcagcaagtgacaaactacagtttgagtacaatgaagaaattcccaagagaatcaag
aaggctgacagctctgtttgcaacaagggaaaggtttatgacatggaactgggtgaagaa
ttttatcttccacagaataaaaaagagagtagacagatagctccagagctttctgacctt
gtcatctactgccaagctgtaaaatttccaggattgtcaactttaaacccatctggctct
aacagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcagatta
agccctggggagacagcagcatataccaaaacatctggaaaaagtcccttggacggcgtg
cggcagacctgggaagaagtctgttctctcagcacagctccgtccctcagtgccatcatc
aggacccccaggtgctaccacatctcctccctgaacgagaatgcggccaagcggctgtgc
cgccggtactctcggaagctgattcagcacaccgcctgccagctgctgagaacctaccct
gccgccactcgcattgactcctccaaccccaatcccctcctgttctggctgcacgggata
cagctggtggcactcaactaccaaacagacgatctccccttacacctaaacacagcaatg
tttgaagctaatggtggctgtggctatgttttgaaaccccctgttttatgggacaagaat
tgtgctatgtaccagcagttttctccactggaaagagatatggaaaacatggaacctgct
ctctattctttaactattgtctctggtcagaatgtgtgtcctagtaacagtacaggaagt
ccatgtattgaaatcgatgtcctgggaatgcctctggatagctgccatttccgcactaaa
cccattcatcgaaatactcttaaccccatgtggaacgaacagtttctcttccgagttcat
tttgaagatcttgtatttcttcgttttgcggttgttgaaaacaacagttcagctgtaact
gcccaaagaatcattccactgaaggctttaaaaagaggatatcggcatcttcagctgaga
aacctccataatgaagtcttagaaatctctagcttgttcataaacagcaggaggatggaa
gagcattccagtggcagtgctgtggcagcatctttgatgttcagcacagaagaaagaaaa
ggtctgatgacatacaaggtcacagtacatgggattccaggtcctgagccttttgccatt
ttcattataaataaagaaattaaagcaaagcagcttcttcaccaaattttgactgcttca
caaaactccataccagtcactccggactgttttttaatggaagaaaaatattttatatct
aaagaaaaaaatgacttcaggaaacaaccattccagagaataatcggtccagaagaagag
attgtgcagattttgaacagctggttcccagaagaaggttatgttggaaggattattttt
aaaatccaggaggaacgcccagaagagaagaacatcttccaagaagagaaggaggtgatg
ctgagctcagaagatgaaagcttctttgtacaagtccatgatgtttctcccgagcagccc
cgaacagtcatcaaagctccccgagtcagcactgcccaggaggtcatccagcagactcta
tgcaaagcaaaatattcttacagcattttgagcaatcccaacccgagtgactacgtgctc
ctagaggaggtactaaaggaacctgctagcaagaagtcttcaacacccaagtcttctcag
agagttctcggggaccaggagtgtgtgttccaggctcaaagcaggtggaagggagccggg
aaatttatccttaagctaaaagagcaggttcaggcagctcgagatgataaaaagaaaggc
atttcctttgctaatgaacttaagaaatttgccaagtctagcaagcagtatcgaggattc
acctcaccttctcagctttcaatagcagaaagtgtccagatgaaggaagaaaaatctgtg
ggcagcttctcttctgagacgacagaccatcacccatga

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