KEGG T02286: 100917022

Sarcophilus harrisii (Tasmanian devil): 100917022

Entry

100917022 CDS T02286

Gene name

PLCE1

Definition

phospholipase C, epsilon 1

Orthology

K05860

phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]

Organism

shr Sarcophilus harrisii (Tasmanian devil)

Pathway

shr00562	Inositol phosphate metabolism
shr01100	Metabolic pathways
shr04020	Calcium signaling pathway
shr04070	Phosphatidylinositol signaling system
shr05205	Proteoglycans in cancer

Module

shr_M00130

Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Class

Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:shr00562]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:shr04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:shr04070]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:shr05205]

SSDB

Motif

Pfam:

PI-PLC-X PI-PLC-Y RasGEF RA EF-hand_like C2 GDPD

Other DBs

NCBI-GI:

395501861

NCBI-GeneID:

100917022

Position

AA seq 2292 aa
MTSEEMVASVPMTQKKVIVASSATDESSENVSDISVMKRHTNKPNKEIPHTLSCLNRFRE
EPIENSLPNIFSVSSKEAISDKNIHENFRDRSMAESMEYININCNNMPNNCQSSYSHFCK
SCDSKSEENLCLDTGISSSLERNMFPGIKLEVDDSSGETNPIRSQSAIIQTNKGHIDNMA
IFHFHYAVQRNASKTFCTISDGLILDDCGNCVQLPNVRDDQKDNYSAYTCSLMELTNDYD
HKNGLKRCDNYDTLRDKYLCLERSCQEVKMACSNKSFCGDDFPGRMPTKPFLSHLEDCTD
NFEEDFFKNKKERSTLLIRRFCKNDKEVKKSVYTGTRAIMRTLPSGHIGPGAWSYIEQKR
SYDIKNFSSSEKTATVQIKQDVNLCLGKSHWFLINNTVRKGEETERTFGSIFHFFGKTLA
LDIIHGHINIGPCLKQCVRDTSCEYRATFQRTSISQYITGSLLEATASLGARSGLLNTFG
GSVGRTMLKERQPCTSTASSINLPSNVSGLSNELIELQHLIQFPEEVACILTEQEQNIYR
QVLPVDYLCFLTRDLGNAECQSKLPCLRATVSASILTPQNNEHSALENLVTRFNEVSSWV
TWLILTAGTMEEKREVFSYLVHIAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSDI
ETMRSLKDAMAQHESSSEYKKVVNRALNIPGCKVVPFCGVFLKELCEILDGTSGFMKLCP
RYNSQDETLEFVADYNGQDNFLQRVGQDGLNNPEKESTVNSIFQIIRSCNRSLEPEEEDS
LSEGDDSRKNSLKDKTRLQFVIGELSDSESDIFEQAKEWDFHGTEEEQKAFKHGTELIPW
YVLSIRADVHQFILQGATVIHYDQDAHLSARCFLRLQPDNSTLTWIKPTTASLANTKAKL
GITGNLADPGKLQSLGNTGLNGLMEGFLDLFSVKAVYMGHPGIDMHTVCVQNKLSNMSLL
ENSVTLLYGLQTTENRLLHFVAPKHTAKMLYNGLLELTKAVRKMKKFPDQRQQWLRKQYV
SLYQEDGRFEGPTLAHAIELFGGRRWTTRNTSPATLSKSVEKPIVQRNNTLGISANKKKK
KILMRGESGEGTDDEMATRKAKMHKECRGRSGSDPQDLNEQEESDQNVIISPCNNLPSRR
ANSLTTAGSPNLAAGATSPVRPLSSPVLSPSNKNQPNTWSSSSWHGRVKGGLKGFQNFMV
SDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCSRSGSESVPLYTNLRIDENTSGLQ
PDLDLLTRNVSDLGLFIKNRQQLSDNQRQISDAIAAASIVTNGSGIESTTLGVCGVGILQ
LNDFLVNCQGEHYTYDEILSIIQKFEPSVSMYQQGLMSFEGFSRFLMDKDNFASQNDESQ
ENVKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMP
IIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKNVFGEK
LVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQTQSNN
GGNANPMSANNEEEEEEEDEYDYDYESLSDDNILEDRPESKSASDKLQFEYNEEIPKRIK
KADSSVCNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNPSGS
NRGKERKSRKSIFGNNPGRLSPGETAAYTKTSGKSPLDGVRQTWEEVCSLSTAPSLSAII
RTPRCYHISSLNENAAKRLCRRYSRKLIQHTACQLLRTYPAATRIDSSNPNPLLFWLHGI
QLVALNYQTDDLPLHLNTAMFEANGGCGYVLKPPVLWDKNCAMYQQFSPLERDMENMEPA
LYSLTIVSGQNVCPSNSTGSPCIEIDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFRVH
FEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRRME
EHSSGSAVAASLMFSTEERKGLMTYKVTVHGIPGPEPFAIFIINKEIKAKQLLHQILTAS
QNSIPVTPDCFLMEEKYFISKEKNDFRKQPFQRIIGPEEEIVQILNSWFPEEGYVGRIIF
KIQEERPEEKNIFQEEKEVMLSSEDESFFVQVHDVSPEQPRTVIKAPRVSTAQEVIQQTL
CKAKYSYSILSNPNPSDYVLLEEVLKEPASKKSSTPKSSQRVLGDQECVFQAQSRWKGAG
KFILKLKEQVQAARDDKKKGISFANELKKFAKSSKQYRGFTSPSQLSIAESVQMKEEKSV
GSFSSETTDHHP

NT seq 6879 nt +upstreamnt +downstreamnt
atgacctctgaagaaatggtagcttctgttcctatgacacagaaaaaagtgatagttgct
agctcagctacagatgaaagtagtgaaaatgtctcagatatcagtgttatgaaaagacat
actaataagccaaacaaagaaatccctcatactctctcatgtttaaacagatttagagaa
gaacctattgaaaattcattgcccaatattttctcagtctcaagtaaagaagcaatcagt
gataagaatatccatgaaaactttagggatagaagcatggcagagtcaatggaatatatt
aacattaactgtaacaacatgcctaataactgccagagttcatatagccatttctgtaag
tcatgtgactctaaatcagaagaaaacctgtgtttggatactggaatttcatcttcactg
gaaagaaacatgtttcctggaattaaactagaagttgatgactcttcaggggaaacaaat
cctataagaagtcaatcagcaattattcagactaacaaaggtcatattgataatatggct
atatttcattttcattatgcagttcagagaaatgcatcaaagactttttgtaccatatct
gatggcttaattttagatgattgcggcaactgtgtacaactaccaaatgttagagatgat
caaaaagacaattactcagcatatacttgtagcttaatggaattgacaaatgattatgac
cataagaatggactgaagagatgtgataactatgataccttaagagataaatatttatgc
ttagaaagatcttgccaggaggttaaaatggcatgttcaaataaaagtttctgtggtgat
gattttcctggaagaatgcctaccaagccctttttgagtcatttggaagattgtactgat
aattttgaagaagatttttttaaaaacaaaaaggagcgatccactttgttaattagaaga
ttttgcaaaaatgataaggaagttaaaaaatctgtttatacaggaaccagagcaattatg
agaaccctgccttctgggcatataggacctggagcttggagttatattgagcagaaaaga
agttatgacattaagaattttagcagttcagagaaaacagcaacagtacagattaagcaa
gatgtgaatctctgtcttggaaaatcccattggtttctgatcaacaacactgtgagaaaa
ggagaagaaacagaacgcacttttggatcaattttccatttctttgggaagactctagcc
ttagatataatccatggacatattaatattggcccatgcttgaagcaatgtgttcgagat
acttcatgtgaataccgagctacctttcaaaggacttcaatttctcagtatatcactggt
tctctattggaagcaactgcgtctctgggtgcaagaagtggccttttaaatacttttgga
ggatcagtaggaagaacaatgttgaaagaacgtcaaccatgtacctccacagccagttca
atcaacttaccttcaaatgtatctggtttaagtaacgagctcatagaacttcaacacctc
attcagttccctgaagaagtggcttgtattctgactgaacaggagcagaatatctaccga
caagtgctacctgtcgactacctttgcttcttaaccagggacttgggaaatgctgaatgc
cagagtaaacttccatgcctcagagctacagtatctgcatctattcttaccccccagaac
aatgagcacagtgctctggaaaaccttgtaacaagatttaatgaggtgagttcttgggtg
acgtggctgatactcacagcaggtaccatggaagaaaaacgggaagtcttctcatattta
gtacacattgcaaaatgctgctggaatatgggcaactacaatgctgttatggaattcttg
gctggcctcaggtcaaggaaagttttaaagatgtggcagtttatggaccagtctgatatt
gaaaccatgagaagcctgaaggatgcaatggcccaacatgaatcttcctctgaatacaag
aaagtggtaaaccgggctctgaatatccctggctgtaaagtggttcctttctgtggtgtc
tttttaaaggagctctgtgaaattctagatggaacatctggatttatgaaactttgccca
cgatataattcacaagatgaaactttagagtttgtagctgattacaatggacaagataat
tttttacaacgagtaggacaagatggcttaaacaacccagagaaagaatccactgtcaac
agtatttttcaaattatccgaagctgcaatcgtagtctggaacctgaagaagaagacagc
ttaagtgaaggcgatgattcaaggaaaaattccttgaaagataaaacccgactacagttt
gtaattggagaactgtctgattcagaaagtgatatttttgagcaggccaaagaatgggat
ttccatggaacggaagaagagcagaaagcattcaagcatggcacagaactcattccctgg
tatgtcttgtcaattagagctgatgtccatcagttcatactccaaggagccactgttatt
cactatgaccaggatgcacatctgtcagcacgatgctttcttcgacttcaacctgataat
agtactttgacctggatcaaacctacaactgcctcactcgccaatactaaagccaaatta
ggcatcacaggaaatttagctgaccctggcaaacttcaatcacttggcaatactggatta
aatggactgatggaaggttttctggatttgttttcagtcaaggctgtgtacatgggacat
cctggcattgatatgcacactgtgtgtgttcagaacaaactcagtaacatgtccctctta
gagaatagtgtgacactgctttatggccttcaaactactgagaatagattattacacttt
gtggcaccaaaacatactgctaaaatgttgtataatggattattagaattaacaaaagct
gtaagaaaaatgaagaaatttcctgaccagcgacagcagtggctaaggaagcaatatgtc
agcctctatcaggaggatggaagatttgaaggtccaactttggctcatgctatcgaactg
tttggtggcagacgttggactacacgaaatacaagtccagcaacactttctaaaagtgtg
gagaaacccattgtgcaaaggaacaacacccttgggataagtgcaaataagaaaaagaaa
aaaatccttatgaggggtgaaagtggagagggtactgatgatgagatggccacacgaaag
gcaaaaatgcataaggaatgccgtggccgcagtggctcagatcctcaagaccttaatgag
caagaagaatcagatcagaatgttattattagtccctgtaataatctgccatccaggaga
gccaattctttgactacagctggatctcctaacttggctgctggagcaacttcaccagtc
agaccactttcctctcctgtattgtcaccttcaaataagaatcagcctaatacatggagc
agcagtagttggcatggccgagttaaaggtggactgaagggatttcaaaatttcatggtt
tcagatagtaacatgagttttgttgaatttgtagagctgttcaagtcattcagtgtacga
agtcgaaaggacctcaaggatctttttgacatctatgctgtaccctgcagtcgatcagga
tctgagtctgtcccactctatacaaacctgagaattgatgaaaataccagtggccttcag
cctgatttagatttgttaaccaggaacgtgtctgacttgggcttgttcattaagaatagg
caacagttatcagacaaccagaggcagatatctgatgccatcgcagctgctagtattgtg
actaatggttctggaatagaaagcaccacgcttggtgtctgtggggttggcatattacag
ctgaatgactttttagtgaattgccaaggggaacactacacttatgatgagatcctcagc
attatccagaaattcgagcctagtgtgagtatgtatcagcaaggtctaatgtcatttgaa
ggattttccaggtttctgatggataaagataattttgcttcccaaaatgatgaatcacag
gagaatgttaaagaattgcagttaccactctcctattattacattgaatcttcacacaac
acatacctcacaggacatcagcttaaaggagagtcctcagtggagctatatagccaggtc
ctcttgcaaggctgtcggagtgtggaattagactgttgggatggtgatgatggaatgcca
attatctatcatggacatacacttactaccaagattcccttcaaggaagtagttgaagcc
attgatcgcagtgccttcatcaactctgacttgcctattataatatctatagaaaatcac
tgttcattgcctcagcaacgaaaaatggcagaaattttcaagaatgtatttggagaaaaa
ctagttgccaaatttttgtttgagagtgatttctctgatgatccaatgcttccttcacct
gaccaacttaggagaaaagtacttcttaaaaacaaaaaactgaaggcacatcagactcca
gtggacatattaaagcaaaaggctcatcaactggcatccatgcaaacacaaagcaataat
ggtggtaatgccaatcctatgtctgccaacaatgaagaagaagaggaggaggaggatgaa
tatgattatgactatgaatctctttctgatgacaacatcctggaagaccggcctgaaagt
aagtcagcaagtgacaaactacagtttgagtacaatgaagaaattcccaagagaatcaag
aaggctgacagctctgtttgcaacaagggaaaggtttatgacatggaactgggtgaagaa
ttttatcttccacagaataaaaaagagagtagacagatagctccagagctttctgacctt
gtcatctactgccaagctgtaaaatttccaggattgtcaactttaaacccatctggctct
aacagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcagatta
agccctggggagacagcagcatataccaaaacatctggaaaaagtcccttggacggcgtg
cggcagacctgggaagaagtctgttctctcagcacagctccgtccctcagtgccatcatc
aggacccccaggtgctaccacatctcctccctgaacgagaatgcggccaagcggctgtgc
cgccggtactctcggaagctgattcagcacaccgcctgccagctgctgagaacctaccct
gccgccactcgcattgactcctccaaccccaatcccctcctgttctggctgcacgggata
cagctggtggcactcaactaccaaacagacgatctccccttacacctaaacacagcaatg
tttgaagctaatggtggctgtggctatgttttgaaaccccctgttttatgggacaagaat
tgtgctatgtaccagcagttttctccactggaaagagatatggaaaacatggaacctgct
ctctattctttaactattgtctctggtcagaatgtgtgtcctagtaacagtacaggaagt
ccatgtattgaaatcgatgtcctgggaatgcctctggatagctgccatttccgcactaaa
cccattcatcgaaatactcttaaccccatgtggaacgaacagtttctcttccgagttcat
tttgaagatcttgtatttcttcgttttgcggttgttgaaaacaacagttcagctgtaact
gcccaaagaatcattccactgaaggctttaaaaagaggatatcggcatcttcagctgaga
aacctccataatgaagtcttagaaatctctagcttgttcataaacagcaggaggatggaa
gagcattccagtggcagtgctgtggcagcatctttgatgttcagcacagaagaaagaaaa
ggtctgatgacatacaaggtcacagtacatgggattccaggtcctgagccttttgccatt
ttcattataaataaagaaattaaagcaaagcagcttcttcaccaaattttgactgcttca
caaaactccataccagtcactccggactgttttttaatggaagaaaaatattttatatct
aaagaaaaaaatgacttcaggaaacaaccattccagagaataatcggtccagaagaagag
attgtgcagattttgaacagctggttcccagaagaaggttatgttggaaggattattttt
aaaatccaggaggaacgcccagaagagaagaacatcttccaagaagagaaggaggtgatg
ctgagctcagaagatgaaagcttctttgtacaagtccatgatgtttctcccgagcagccc
cgaacagtcatcaaagctccccgagtcagcactgcccaggaggtcatccagcagactcta
tgcaaagcaaaatattcttacagcattttgagcaatcccaacccgagtgactacgtgctc
ctagaggaggtactaaaggaacctgctagcaagaagtcttcaacacccaagtcttctcag
agagttctcggggaccaggagtgtgtgttccaggctcaaagcaggtggaagggagccggg
aaatttatccttaagctaaaagagcaggttcaggcagctcgagatgataaaaagaaaggc
atttcctttgctaatgaacttaagaaatttgccaagtctagcaagcagtatcgaggattc
acctcaccttctcagctttcaatagcagaaagtgtccagatgaaggaagaaaaatctgtg
ggcagcttctcttctgagacgacagaccatcacccatga

All links

Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (26)   

Download RDF

DBGET integrated database retrieval system