KEGG T02286: 100918097

Sarcophilus harrisii (Tasmanian devil): 100918097

Entry

100918097 CDS T02286

Gene name

CACNA2D2

Definition

calcium channel, voltage-dependent, alpha 2/delta subunit 2

Orthology

K04859

voltage-dependent calcium channel alpha-2/delta-2

Organism

shr Sarcophilus harrisii (Tasmanian devil)

Pathway

shr04010	MAPK signaling pathway
shr04260	Cardiac muscle contraction
shr05410	Hypertrophic cardiomyopathy (HCM)
shr05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
shr05414	Dilated cardiomyopathy

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:shr04010]
Organismal Systems; Circulatory system; Cardiac muscle contraction [PATH:shr04260]
Human Diseases; Cardiovascular diseases; Hypertrophic cardiomyopathy (HCM) [PATH:shr05410]
Human Diseases; Cardiovascular diseases; Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:shr05412]
Human Diseases; Cardiovascular diseases; Dilated cardiomyopathy (DCM) [PATH:shr05414]

SSDB

Motif

Pfam:

VWA_N VGCC_alpha2 Cache_1 VWA VWA_3 VWA_2 Cache_2 VWA_CoxE

Other DBs

NCBI-GI:

395516371

NCBI-GeneID:

100918097

Position

AA seq 1082 aa
MQYWSRRLEQEIDGVMRIFGGVKQLREIYKDNRNLFEIEENVPQKLVEKVAGDIEGLLAK
KVRALKRLADAAEKFQKAHRWQDNIKEEDIQYYDSKADAELEDPEGEEFEREKPSTLQLD
FVEDPNFKNKVNYSYTAVQIPTDIYKGSTVILNELNWTEALEDVFVENRKEDPSLLWQVF
GSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLRLM
KTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFNHLVQANVRNKKVFKEAVQNMVAKGTTG
YKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQ
HNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGNEAKQVQWTNVYE
DALGLGLVVTGTLPVFNLTQDGSGERKNQLILGVMGIDVALNDIKKLTPNYTLGANGYVF
SIDLNGYVLLHPNLKPQITNFREPVTLDFLDAELEDENKEEIRKSMIDGKRGHKQIKTLI
KSLDERYIDEVIRNYTWVPIKSTNYSLGLVLPPYSTFYLQANLSDQILQVKLSISKLKDF
EFLLPNSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNL
ILDTGITQQLVEKVWKDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWEENPEPFNASFY
RRSLDNQGYIFKPPYHDSLLRPLELENNTVGILVSTAVELTLGGRTIKPAVVGVKLDLEA
WAEKFKVLASNRTDRDQPQKCGPNSHCEMDCDVNNEDLLCVLIDDGGFLVLSNQYNQWDQ
VGKFFSEVDANLMLALYNNSFFTRKESFDYQAVCTPRAQSNTGAAPRGVFVPTIADFLNL
AWWTSAAAWSLLQQLLYGFTYHSWFQAEDAAAEGSETRESSCIMKQTQYYFSTTNASYNS
IIDCGNCSRLFHAQRLANTNLLFVVAEKPLCSQCESGKLLQAERRSDGPEQCELVQKPRY
RKGPHICFDYNATEDTSDCGRGASFRASLGILVSLQLLLLLGLSPTPLPLPWPHSDLHHH
HL

NT seq 3249 nt +upstreamnt +downstreamnt
atgcagtactggtctcgaaggctggaacaagagattgatggagtgatgagaatctttggt
ggggtcaagcagctgagagagatctacaaggacaacagaaacttgtttgagattgaggag
aacgtcccccaaaaacttgtggaaaaggtggcaggagatattgagggcctactggccaag
aaggtccgggctctgaagagactagctgatgctgcagagaaattccagaaggcccatcgt
tggcaagacaacatcaaggaagaagatatccagtactatgactccaaagcagatgctgag
ctggaagaccccgagggtgaggagtttgagagggaaaagcccagtactctgcagctggac
ttcgttgaagaccccaactttaaaaacaaggtcaactactcatatacggctgtccagatt
cctacggacatctacaaaggctccacagtgatcctgaatgagctcaactggacagaagcc
ttagaggatgtatttgtagagaaccgtaaggaagatccatcactgctatggcaggttttt
ggcagtgctacgggggtcacccgatattatccagctactccttggagagcaccaaaaaag
attgacctgtatgatgtccgccggagaccctggtacatccaaggagcttcctctcctaag
gacatggtcatcatcgtggatgtaagcggcagtgtgagcggactgacactgaggctgatg
aagacatctgtctgcgagatgctggacaccctctccgatgacgactacgtcaatgtggca
tcgttcaatgagaaggcccagcccgtatcctgcttcaaccacctggttcaggccaacgtg
cgcaacaaaaaggttttcaaggaagctgtgcagaacatggtggcaaaaggcaccacaggt
tacaaggctggctttgagtatgcctttgatcagctccagaattccaacatcacccgggct
aactgcaacaaaatgatcatgatgttcaccgatggaggggaggaccgagtgcaggatgtg
ttcgagaagtacaattggcccaacaggacggttcgggtattcactttttccgtaggacag
cacaactacgatgtcactcccctgcagtggatggcctgtgccaataaaggttactatttt
gagatcccctccattggggctatccgaatcaacacacaggagtacctggatgttctgggc
agaccaatggttctcgcaggcaacgaggctaagcaggtgcagtggaccaatgtgtatgaa
gatgctctgggcctagggctggtagtgactggaaccctccccgtgttcaacctgacccag
gatggcagtggggagagaaagaaccagctcatcctgggtgtgatgggcatcgatgtggct
ctgaacgacatcaagaagctgacaccaaattacacgcttggtgcaaatggttatgtgttc
tccattgaccttaatggctatgtcctgctccaccctaacctgaagccccagatcaccaac
tttcgggagccagtgaccttggatttcctagatgctgaactagaagatgaaaacaaggaa
gaaatccgaaagagcatgattgatgggaaaaggggacacaaacaaatcaagactctcatc
aaatccctggatgagagatacattgatgaagtcattcgaaactatacctgggtcccgatc
aaaagtaccaattacagccttgggctggtcttgcctccttacagcacgttctatctacaa
gccaacctcagtgaccagatcctgcaggtcaagttgtcaatcagcaaactgaaggatttt
gagttcctgctcccaaacagctttgaatctgaaggacatgttttcattgctcccagagaa
tactgcaaggacctgaatgcctcagacaacaacacggagtttctcaagaactttattgag
ctcatggagaaggtgactccagactccaagcagtgtaataacttcctcctacacaacctg
attctggacaccggcatcacacagcaactggtggagaaggtgtggaaggaccaggacctc
aacacgtacagcctcctcgctgtgtttgctgctacagacgggggcatcacccgggttttc
cccaacaaggcagccgaggactgggaggagaaccccgaacccttcaatgccagcttttac
cggcgtagcctggacaaccagggctacatcttcaagcctccctatcatgattctctcctc
aggcctctggagctggagaacaacactgtgggcatcctggtgagcacagctgtggaactc
acccttgggggaaggacaatcaagcctgcggtggtgggagtgaagctggatctggaagcc
tgggctgagaagttcaaggtgttggccagcaatcgaacagatcgggaccagccacagaag
tgtggccccaacagccactgtgagatggactgtgacgtcaacaacgaggatctgctctgc
gttctcattgatgatggtggattcttggttctctccaaccagtacaatcagtgggaccag
gtgggcaaattcttcagcgaggtggacgccaacctcatgcttgcactgtataataactcc
ttcttcactcgcaaagagtcctttgactaccaagctgtgtgcaccccccgggctcagagc
aacacgggcgctgccccccgaggggtctttgttcctaccatcgccgacttcctcaacctg
gcctggtggacttcagccgcagcctggtccttgctccagcagcttctctatggattcacc
tatcacagttggttccaagcagaggatgcagcggccgaaggctcggagaccagggagagc
agctgcatcatgaagcagacccagtactacttcagcaccaccaatgcctcctacaacagc
atcatagactgcgggaactgctccaggctgttccacgcccaaagactggccaacaccaac
ctgctgttcgtcgtggccgagaagcccctgtgcagccagtgtgagtccggcaagctgctg
caagcagagaggcgctctgacgggccggagcagtgtgagctggtacagaagccacgatac
aggaagggacctcacatctgctttgactacaacgcgacggaagatacctcagactgtggt
cgaggagcctccttcagagcatccctgggcattctggtgtccctgcagctgctgctcctc
ctgggcctgtcccccacgcccctgcccctgccctggccccacagtgacctccaccaccac
cacctctga

All links

Pathway (5)   
   KEGG PATHWAY (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (20)   

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