KEGG   Sarcophilus harrisii (Tasmanian devil): 100918168Help
Entry
100918168         CDS       T02286                                 

Gene name
GCK
Definition
glucokinase (hexokinase 4)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100918168 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100918168 (GCK)
   00052 Galactose metabolism
    100918168 (GCK)
   00500 Starch and sucrose metabolism
    100918168 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    100918168 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    100918168 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    100918168 (GCK)
   04910 Insulin signaling pathway
    100918168 (GCK)
   04917 Prolactin signaling pathway
    100918168 (GCK)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100918168 (GCK)
   04950 Maturity onset diabetes of the young
    100918168 (GCK)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100918168 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 475 aa AA seqDB search
MVFTQEAIKIKMNEMRVYIHQEDLLVEQILSEFRLQEEDLKKVMRRMQKEMDRGLRLETH
EEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSI
PEDAMTGTAEMLFDYISECISDFLDKHHMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKG
FKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGC
NACYMEEMENVELVEGDEGRMCVNTEWGAFGDAGELDEFLLEYDRVVDETSLNPGQQLYE
KIIGGKYMGEIVRLVLLKLVDENLLFNGEASEQLRTRGAFETRFVSQVESDSGDRKQIYN
ILSTLGLLPSTTDCDIVRMVCESVSTRAAQMCSAGLAGVINRMRESRSEEVMRITVGVDG
SVYKLHPSFKHRFHATVRQLAPCCDITFIQSEEGSGRGAALVSAVACKKACMLSQ
NT seq 1428 nt NT seq  +upstreamnt  +downstreamnt
atggtcttcacccaagaggccatcaagatcaagatgaacgagatgagggtatacatccat
caagaagacctcttggtggaacaaatcttgtctgagttcaggctacaggaagaagaccta
aagaaagtgatgaggaggatgcagaaggagatggaccggggcctgcggctggagacccat
gaagaagccagtgtgaagatgctccccacttacgtgcgctccacccccgaggggtcagaa
gtgggagatttcctctccttggatctgggcggcacaaatttccgggtaatgttggtaaaa
gtgggagaaggagaggagggtcagtggagtgtgaagacaaaacatcagatgtactccatc
cctgaggatgccatgacaggaacggcagaaatgctatttgactacatctctgaatgcatt
tctgatttcctggacaaacaccatatgaaacataaaaagttgcctctgggcttcacattc
tccttccccgtgcggcatgaagacattgacaagggaatccttctcaactggacaaaaggc
ttcaaagcatcaggtgccgaagggaacaacatagtcgggctcttgagagatgctatcaag
cggcgtggggactttgagatggatgttgttgccatggtcaacgacacagtggcgacaatg
atttcctgctactatgaagaccgccagtgtgaggtcggcatgattgttggcacggggtgt
aacgcctgctacatggaggagatggagaacgtggaactggtggaaggggacgaaggccgc
atgtgtgtgaacaccgagtggggagcctttggggatgctggagaacttgacgagttcctg
ctggagtatgaccgggtggtggatgagacctccctgaaccccggtcagcagctttatgag
aagatcatcgggggcaagtacatgggggagatcgtgaggctggttctactgaaactggta
gatgagaatttgctcttcaacggggaagcatctgaacagctgaggacccggggggccttc
gagacccgtttcgtctcccaagtggagagtgattctggggaccgaaagcagatctacaac
atcctgagtactctgggactgcttccctccaccacagactgtgatattgtgcgcatggtc
tgtgagagtgtctccacccgggcagcccagatgtgctccgcagggttagcaggtgtcatc
aaccgcatgcgggaaagtcgcagcgaggaggtcatgaggatcaccgtcggtgtggacggc
tctgtctacaaactgcaccccagcttcaaacaccgattccatgctactgtgcggcagctg
gccccctgttgtgacatcacctttatccagtcagaggagggcagcggccggggggctgcc
cttgtctctgccgtggcctgcaaaaaggcctgcatgcttagccagtga

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