KEGG   Sarcophilus harrisii (Tasmanian devil): 100918168Help
Entry
100918168         CDS       T02286                                 

Gene name
GCK
Definition
(RefSeq) glucokinase (hexokinase 4)
  KO
K12407  
glucokinase [EC:2.7.1.2]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Glucagon signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100918168 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100918168 (GCK)
   00052 Galactose metabolism
    100918168 (GCK)
   00500 Starch and sucrose metabolism
    100918168 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    100918168 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100918168 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    100918168 (GCK)
   04910 Insulin signaling pathway
    100918168 (GCK)
   04922 Glucagon signaling pathway
    100918168 (GCK)
   04917 Prolactin signaling pathway
    100918168 (GCK)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    100918168 (GCK)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100918168 (GCK)
   04950 Maturity onset diabetes of the young
    100918168 (GCK)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100918168 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Ensembl: 
Position
1
AA seq 533 aa AA seqDB search
MIETGKINQQEGRSYLSKSWSVDALEKGFDSPLEEDLEDFCSEARRALGXSQEWACLWAA
HLRLEAAQMLDYRARMDSSQKEKVEQILSEFRLQEEDLKKVMRRMQKEMDRGLRLETHEE
ASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPE
DAMTGTAEMLFDYISECISDFLDKHHMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFK
ASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNA
CYMEEMENVELVEGDEGRMCVNTEWGAFGDAGELDEFLLEYDRVVDETSLNPGQQLYEKI
IGGKYMGEIVRLVLLKLVDENLLFNGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNIL
STLGLLPSTTDCDIVRMVCESVSTRAAQMCSAGLAGVINRMRESRSEEVMRITVGVDGSV
YKLHPSFKHRFHATVRQLAPCCDITFIQSEEGSGRGAALVSAVACKKACMLSQ
NT seq 1602 nt NT seq  +upstreamnt  +downstreamnt
atgattgaaacaggaaaaataaatcaacaggaaggtagatcatacctatccaaatcctgg
tcagtggacgcactggaaaaaggatttgactctccattggaggaagacttggaggatttc
tgctctgaggcgagaagagcacttggtngttctcaggagtgggcttgtctttgggcagct
cacctgagattggaagctgcccagatgctggattacagagccaggatggacagctcccag
aaggagaaggtggaacaaatcttgtctgagttcaggctacaggaagaagacctaaagaaa
gtgatgaggaggatgcagaaggagatggaccggggcctgcggctggagacccatgaagaa
gccagtgtgaagatgctccccacttacgtgcgctccacccccgaggggtcagaagtggga
gatttcctctccttggatctgggcggcacaaatttccgggtaatgttggtaaaagtggga
gaaggagaggagggtcagtggagtgtgaagacaaaacatcagatgtactccatccctgag
gatgccatgacaggaacggcagaaatgctatttgactacatctctgaatgcatttctgat
ttcctggacaaacaccatatgaaacataaaaagttgcctctgggcttcacattctccttc
cccgtgcggcatgaagacattgacaagggaatccttctcaactggacaaaaggcttcaaa
gcatcaggtgccgaagggaacaacatagtcgggctcttgagagatgctatcaagcggcgt
ggggactttgagatggatgttgttgccatggtcaacgacacagtggcgacaatgatttcc
tgctactatgaagaccgccagtgtgaggtcggcatgattgttggcacggggtgtaacgcc
tgctacatggaggagatggagaacgtggaactggtggaaggggacgaaggccgcatgtgt
gtgaacaccgagtggggagcctttggggatgctggagaacttgacgagttcctgctggag
tatgaccgggtggtggatgagacctccctgaaccccggtcagcagctttatgagaagatc
atcgggggcaagtacatgggggagatcgtgaggctggttctactgaaactggtagatgag
aatttgctcttcaacggggaagcatctgaacagctgaggacccggggggccttcgagacc
cgtttcgtctcccaagtggagagtgattctggggaccgaaagcagatctacaacatcctg
agtactctgggactgcttccctccaccacagactgtgatattgtgcgcatggtctgtgag
agtgtctccacccgggcagcccagatgtgctccgcagggttagcaggtgtcatcaaccgc
atgcgggaaagtcgcagcgaggaggtcatgaggatcaccgtcggtgtggacggctctgtc
tacaaactgcaccccagcttcaaacaccgattccatgctactgtgcggcagctggccccc
tgttgtgacatcacctttatccagtcagaggagggcagcggccggggggctgcccttgtc
tctgccgtggcctgcaaaaaggcctgcatgcttagccagtga

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