KEGG   Sarcophilus harrisii (Tasmanian devil): 100919206Help
Entry
100919206         CDS       T02286                                 

Gene name
PLCG2
Definition
phospholipase C, gamma 2 (phosphatidylinositol-specific)
Orthology
K05859  
phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Osteoclast differentiation
Platelet activation
Natural killer cell mediated cytotoxicity
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100919206 (PLCG2)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100919206 (PLCG2)
   04012 ErbB signaling pathway
    100919206 (PLCG2)
   04370 VEGF signaling pathway
    100919206 (PLCG2)
   04064 NF-kappa B signaling pathway
    100919206 (PLCG2)
   04066 HIF-1 signaling pathway
    100919206 (PLCG2)
   04020 Calcium signaling pathway
    100919206 (PLCG2)
   04070 Phosphatidylinositol signaling system
    100919206 (PLCG2)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100919206 (PLCG2)
   04650 Natural killer cell mediated cytotoxicity
    100919206 (PLCG2)
   04662 B cell receptor signaling pathway
    100919206 (PLCG2)
   04664 Fc epsilon RI signaling pathway
    100919206 (PLCG2)
   04666 Fc gamma R-mediated phagocytosis
    100919206 (PLCG2)
   04670 Leukocyte transendothelial migration
    100919206 (PLCG2)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100919206 (PLCG2)
  Nervous system
   04722 Neurotrophin signaling pathway
    100919206 (PLCG2)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100919206 (PLCG2)
  Development
   04380 Osteoclast differentiation
    100919206 (PLCG2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100919206 (PLCG2)
   05206 MicroRNAs in cancer
    100919206 (PLCG2)
   05205 Proteoglycans in cancer
    100919206 (PLCG2)
   05214 Glioma
    100919206 (PLCG2)
   05223 Non-small cell lung cancer
    100919206 (PLCG2)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100919206 (PLCG2)
Enzymes [BR:shr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100919206 (PLCG2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
1
AA seq 1264 aa AA seqDB search
MTTKINLESLPEYEKSQIKRTLELGTVMTLFSLKKSNPERRTVQVITETRQVAWSKTADK
IEGFLDLMEIKEIRPGKNSKDFERGKASRQKEDCCFTIFYGTQFVLNTLSLAVDSKEDAN
KWLCGLTILHQEAQNASTPAIIESWLRKQIYSVDQTRRNSISFRELKTILPLVNFKVSSA
KFLKDKFLEIGAYKDELSFEQFHLFYKKMMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQEIWAQDLSKVREQMTKFIDDTMRETAEPFLFVDEFLTYLFSKENS
IWDDKYDSVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTESYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVSSQFPVILSIEEHCCVEQQRHMARV
FKDVFGDLLLTKPTEASADQLPSPAQLKEKIIIKHKKLGPRGDVDINIEDRKEEKKQQGE
LYMWDTIDQKWYRHYCAIADEKLSFSDVIEQNMEEDSAKDVAQTDLHFGEKWFHKRMEKR
TSAEKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTPEGGAMKYY
LTDNLMFNSIYDLIQHYREAHLRCAEFELRLTDPVPNPNPHESKAWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGGDAYAITFRAKGKVKHCRINKDGHHFVLGTSAYFESLVELVNYY
EKHALYRKMRLRYPVTPELLERYNTERDINSLYDVRMYVDPSEINPSTPQRTVKALYDYK
AKRGDELSFCRGALIHNVSKESGGWWKGDYGGRIQQYFPSNYVEDISTVDFEELEKQIIE
DNPLGSLCRGILDLNTYNVVKVPHGKNQKPFVFILEPKKPNDPPIEFATDKVEELFEWYQ
SIREITWKNATVENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVET
KADSIVRQKPIDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYM
QLNHALFALNGRTGYVLQPESMRNENYDPTPPESQRKILMTLTVKVLGARHLPKLGRSIA
CPFVEVEICGTEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEEDM
FSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCR
QLRRRQEELNNELFLYDSHQNLRNANRDALMNEFNVNENQLQLYQEKCNRRLREKRVSNS
KFYS
NT seq 3795 nt NT seq  +upstreamnt  +downstreamnt
atgaccaccaagatcaacttagagagtcttcctgaatatgagaagagtcagatcaagagg
accctggaattgggaactgtcatgaccctgtttagccttaagaaatctaaccctgagagg
agaacggtccaggtcatcacagagaccaggcaggtggcatggagtaagacggctgacaag
atcgaagggttcttggacctaatggagataaaggaaatccgcccagggaaaaactcaaag
gactttgaacgtgggaaagccagtcgccagaaagaagattgctgctttaccatattttat
ggcacccagtttgtgctcaacaccctgagtttagcagtggactccaaagaagatgctaat
aaatggctttgtggcttgacaattttgcaccaagaagcccagaatgcctcaacaccagct
attattgagagctggctaagaaagcaaatttattctgtagatcaaactcggagaaatagt
atcagcttcagagaactgaagaccattcttcctttagtaaacttcaaagtgagcagcgcc
aagttcctgaaagacaaattcctggaaataggtgcctacaaggatgaactcagctttgaa
cagttccacttattctacaaaaagatgatgtttgagcaacagaaatcaattcttgatgag
ttcaaaaaagattcatctgtgtttattctgggaaatacagatcggccagatgcatctgct
gttcacctgcatgacttccagaggtttctcctgcatgaacagcaggaaatctgggcacag
gatctaagtaaagtaagagagcagatgacaaaatttatagatgacactatgagagaaaca
gctgaaccattcctgtttgtcgatgagttcctcacttatctgttttcaaaagaaaacagc
atttgggatgataaatatgactctgttgatatgcaagacatgaataatcctttgtctcat
tattggatttcttcatctcataacacgtacctcactggagatcaacttcgaagtgaatct
tctactgaatcatacattcgatgtcttcgaatgggttgccggtgtatagagttggattgc
tgggatggacctgatggaaagccaatcatctatcatggctggacacgaacaacgaaaatc
aagtttgatgatgtggtgcaggccatcagagaccatgcttttgtctcctcacagttccca
gtgattctctccattgaagagcactgttgtgtagaacagcagcgtcatatggccagggta
tttaaagacgtgtttggggatctcctccttacaaaacccactgaagccagtgctgaccag
ctgccatcccctgcccagctgaaagaaaagatcatcattaagcacaagaagctgggtccc
agaggagatgtggacatcaacattgaagacagaaaagaagaaaaaaaacagcaaggggaa
ctatacatgtgggacaccattgatcagaagtggtatcgccactattgtgccatagctgat
gagaagttgtccttcagtgatgttatagagcagaatatggaagaagactcagcaaaggac
gtagcacagactgacctgcattttggtgagaagtggtttcataaaagaatggagaagagg
acaagtgctgagaaattactgcaagaatattgtgctgaaaccggaggaaaggatggaacc
ttcttagtccgtgaaagtgagactttccccaatgactacacattgtccttctggagatca
ggcagagtccagcactgtcgaatacggtcgactcctgagggaggggccatgaagtattat
ttgactgacaacctcatgttcaacagcatctatgacttgattcaacactaccgagaagcc
cacctaagatgtgctgaatttgaacttcgtttgacagacccagtgcccaatcccaatcct
catgaatcaaaagcttggtactatgatagcctgagcagaggagaagctgaagacatgttg
atgagaattccccgagatggagccttcctgattaggaaaagagaagggggagatgcatac
gccattactttcagagccaagggaaaagtgaaacactgccggattaacaaagatggacat
cactttgtgctggggacgtctgcttactttgaaagcttagtggaattggtcaactactat
gaaaagcatgcactctacaggaaaatgagattgcgctatcctgtgactccagagctgctg
gaacgttacaatactgaaagggacataaattcactttatgatgtcaggatgtatgtggat
cccagtgaaattaacccttcaacgcctcagagaactgtgaaggctttatacgactacaaa
gccaagcgtggggatgagctcagcttctgtcggggggccctcatccataatgtctccaag
gagtctggtggctggtggaagggtgattatggaggaaggattcagcaatattttccatct
aattatgtggaagacatatcaacagttgattttgaagagctggaaaaacagattattgaa
gataaccctttaggatctctgtgcagaggaatcttggatcttaacacctataatgttgtg
aaagtaccacatggaaaaaaccagaaaccatttgtcttcatcctggaacccaagaaaccc
aatgatcctcctatagagtttgcgactgacaaagtggaagagctctttgagtggtaccag
agcatcagggaaatcacctggaagaatgcaacagtggagaacaacatgaaatattgggag
aagaaccaatcgattgccatagaactatctgatttggttgtctactgtaagccaacaagt
aaaaccaaggataatttagaaaatcctgatttcagagaaattcgctctttcgtggagacc
aaagccgacagcattgttaggcagaagccaattgatcttttgaagtacaatcaaaaggga
ctgactcgggtctaccccaaaggtcaaagggtagactcatcaaattatgatccttttcga
ctttggctttgtggctcccagatggttgccctgaatttccagactgcagataaatatatg
cagctgaatcatgctttatttgcacttaatggtcggactggctacgtcctacagcctgaa
agcatgaggaatgaaaactatgatccaacacctccagagtcacaaagaaagatcctgatg
accttgacagtgaaggtcctgggggctcgtcatctacccaagcttggccgaagcattgcc
tgtccatttgtagaagtggaaatttgtgggactgagtatgataataacaaattcaagact
actgtagtaaatgataatggcctgagtccagtctgggcttctactcaggaaaaagtgaca
tttgagatttatgacccaaatcttgcatttctacgatttgttgtgtatgaggaggatatg
ttcagcgatcccaactttctggcacatgctacttatcccattaaaggaatcaaatcaggg
tttagatcagttcctcttaaaaatggttacagtgaagatattgaactggcctctcttcta
gttttctgtgagatgcgtcctgtgttggaaagtgaagaagagctttattcttcctgtcgc
cagcttcgaaggaggcaagaagagctgaataatgagcttttcttgtatgactctcatcag
aacttacgtaacgccaacagagatgctctcatgaatgaattcaatgtcaatgagaatcag
ttgcagttgtatcaggaaaagtgcaacaggagattaagggagaagagagtcagtaacagc
aaattctactcctag

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