KEGG   Sarcophilus harrisii (Tasmanian devil): 100922649
Entry
100922649         CDS       T02286                                 
Symbol
CAPN2
Name
(RefSeq) calpain-2 catalytic subunit
  KO
K03853  calpain-2 [EC:3.4.22.53]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04141  Protein processing in endoplasmic reticulum
shr04210  Apoptosis
shr04217  Necroptosis
shr04218  Cellular senescence
shr04510  Focal adhesion
shr05010  Alzheimer disease
shr05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:shr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100922649 (CAPN2)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100922649 (CAPN2)
   04217 Necroptosis
    100922649 (CAPN2)
   04218 Cellular senescence
    100922649 (CAPN2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100922649 (CAPN2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100922649 (CAPN2)
   05022 Pathways of neurodegeneration - multiple diseases
    100922649 (CAPN2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:shr01002]
    100922649 (CAPN2)
Enzymes [BR:shr01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.53  calpain-2
     100922649 (CAPN2)
Peptidases and inhibitors [BR:shr01002]
 Cysteine peptidases
  Family C2: calpain family
   100922649 (CAPN2)
SSDB
Motif
Pfam: Peptidase_C2 Calpain_III EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_7
Other DBs
NCBI-GeneID: 100922649
NCBI-ProteinID: XP_031822926
Position
4:complement(389078936..389163688)
AA seq 700 aa
MSGIAAKVVKDREAAAGLGSHELAVKYLNQDYETLLSECLEQGRLFEDPMFPAIGSSLGF
KELGPYSSKTQGVVWKRPTEICSDPQFIVEGATRTDICQGALGDCWLLAAIASLTLNEEI
LTRVVPKNQSFQENYAGIFHFQFWQYGEWVDVVIDDRLPTKNDELLFVHSAEGSEFWSAL
LEKAYAKVNGCYEALSGGATTEGFEDFTGGIAEWYDLKKAPDNLFVIIQKALQKGSLLGC
SIDITSAADSEAITFQKLVKGHAYSVTGAEEVEFRGSLQKLIRIRNPWGEVEWTGKWSDN
CPNWNSIDPDERERLTRKFEDGEFWMSFSDFLRHYSRLEICNLTPDTLISDSYKKWRLTK
MDGTWRRGSTAGGCRNYPNTFWMNPQYMIKLEEEDEDSDGSEPGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEEFSGRTNLHLPKNFFLTTRARERSDTFINLREVLNRFKLPAG
EYVIVPSTFEPHKNGDFCLRVFSETKTDSQIVDDEIEAELDENDVDEDAIEDNFRKLFAQ
LAGEDAEISAFELQTILRRVLAKRPDIKSDGFSIETCKIMVDMLDADGSGKLGLKEFYLL
WSKIQKYQRIYKEMDIDKSGTMNAYEMRKALEEAGFKLPYQLHQVIVARFADDDLIIDFD
NFVRCLVRLETLFKIFKQLDPENTGTIELNITSWLCFSVL
NT seq 2103 nt   +upstreamnt  +downstreamnt
atgtcgggcatcgcagccaaagtggtgaaagatcgggaggcggcagccggcctgggctct
cacgagctggcagtcaaatacctcaaccaggactacgagactctcctcagcgaatgcctt
gagcagggcagactctttgaggaccctatgttcccggcgattggatcttccctggggttc
aaggaactgggaccgtactcgagcaaaactcagggcgtcgtctggaaaagacccacggaa
atctgctctgatccccagtttattgttgaaggagcaacccgcacagacatctgtcaagga
gccctgggtgactgctggttgctggcagccattgcttccctcaccctgaatgaagaaatc
ctgacgagggtagttcctaaaaaccaaagcttccaagaaaactatgctggaatcttccat
tttcagttttggcaatatggtgaatgggtagacgtggtgatcgatgacaggctacccaca
aagaatgatgagctcctctttgtccactctgctgaaggaagcgaattctggagtgccctc
ttggagaaagcctacgccaaggtcaatggatgttatgaagctctctcaggaggggctacc
acagagggctttgaggacttcactggtgggatagctgagtggtatgatctgaagaaagcc
cctgacaatttgtttgtcatcatccagaaggccctgcagaagggttctctccttggctgt
tccattgatatcacaagtgctgcagactcagaagcgataactttccagaagctggtgaaa
ggacatgcttactcagttactggagcagaagaggtggagttcagaggaagtctgcagaag
ctgattcgcatcagaaacccctggggagaagttgaatggactggaaagtggagtgacaac
tgccctaactggaacagcatagaccccgatgagagggagaggctaaccaggaaatttgaa
gacggagaattctggatgtctttcagtgacttcctaagacactattcccgcctagagatc
tgcaacctcaccccagacacattaatcagtgattcctacaagaaatggagactcaccaag
atggatgggacctggagacggggttctacggcagggggctgcaggaactatccaaacact
ttctggatgaacccccagtacatgatcaagctagaagaggaggatgaggattctgacggc
tctgagccaggatgcaccttcctagtgggtctcatccagaaacaccgacgacgccaaagg
aaaatgggagaggatatgcacactattggctttggtatctatgaggttcctgaggagttt
tctggtcggaccaacttacacctccccaaaaacttctttctgacgaccagagcaagggag
aggtcggatacattcatcaatctccgagaagtgttgaatcgcttcaagctgcccgctgga
gaatacgtcatcgtgccttctacttttgaaccccacaagaatggggatttctgccttcga
gtcttttcagagacgaaaactgattctcaaattgttgatgatgaaattgaggctgagctg
gacgagaatgatgttgatgaagatgccattgaggacaatttcaggaaactgtttgctcaa
ctggcaggagaggatgcagagatttctgcctttgagctgcagactatcctgagaagagtc
ctagcaaaacgtccagatatcaagtcggatggcttcagcatcgagacttgcaagatcatg
gtggacatgctggatgctgatgggagtggtaaactgggtctgaaggaattctaccttctc
tggtcaaaaatacaaaaatatcagagaatttacaaggagatggacattgataagtccgga
accatgaatgcctatgagatgcgtaaagcattagaagaagcaggttttaagctaccctat
cagctccatcaggtcattgtggctcggttcgcggatgacgatctcatcatcgacttcgat
aattttgttcggtgcttagttcgactggaaacactgttcaagatatttaagcagttggac
cctgagaacaccggaacgatagaactcaatattaccagttggctgtgtttttcagtcctt
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (29)   

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