KEGG   Sarcophilus harrisii (Tasmanian devil): 100923119Help
Entry
100923119         CDS       T02286                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100923119 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100923119 (PLCG1)
   04015 Rap1 signaling pathway
    100923119 (PLCG1)
   04012 ErbB signaling pathway
    100923119 (PLCG1)
   04370 VEGF signaling pathway
    100923119 (PLCG1)
   04064 NF-kappa B signaling pathway
    100923119 (PLCG1)
   04066 HIF-1 signaling pathway
    100923119 (PLCG1)
   04020 Calcium signaling pathway
    100923119 (PLCG1)
   04070 Phosphatidylinositol signaling system
    100923119 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100923119 (PLCG1)
   04660 T cell receptor signaling pathway
    100923119 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    100923119 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    100923119 (PLCG1)
   04670 Leukocyte transendothelial migration
    100923119 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100923119 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100923119 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100923119 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100923119 (PLCG1)
   05206 MicroRNAs in cancer
    100923119 (PLCG1)
   05205 Proteoglycans in cancer
    100923119 (PLCG1)
   05214 Glioma
    100923119 (PLCG1)
   05223 Non-small cell lung cancer
    100923119 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100923119 (PLCG1)
Enzymes [BR:shr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100923119 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 982 aa AA seqDB search
MAGVGAPFANGCGACAPSEAEALHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAVDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIKGLNWLVTDTVQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDMEQRSGDITYGQFAQLYRSLMFSAQKSMDFPFLEAGTLRG
GDRPELCRVSLSEFQQFLLEYQGELWATDRLQVQEFMLSFLQDPLREIEEPYFFLDEFVT
FLFSKENNIWNSQLDSVCVDTMNNPLSQYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVTSEYPVILSIEDHCSIA
QQRNMAQYFKKVFGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVM
YSENDISNSIKNGILYLEDPINHEWYPHYFVLTSSKIYYSEETNSDQGNEDEEEPKEVSS
SAELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGSPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLTEPVPQT
NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRSEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKMGTAEPDYGALYEGRNP
GFYVEANPMPTFKNGRGIVCPFVEIEVAGADYDNMKHKTEFVVDNGLNPVWPAKPFHFQI
SNPEFAFLRFVVYEEDMFSDQNFLAQATFLVKGLKTGYRAVPLKNNYSEDLELASLLIKI
DIFPAKQENGEISPFGSSSFRERGSESSGQLLHGRAREGSFEARYQQPFEDFRISQEHLA
DHFDSRERRALRRTRINGDNRL
NT seq 2949 nt NT seq  +upstreamnt  +downstreamnt
atggcaggggtcggggcccccttcgccaatggctgcggggcctgcgctccgtcggaggcc
gaggctcttcacctctgccggagtttggaagtgggcacagtcatgaccttgttctactcc
aagaaatcccagcgacctgagaggaaaaccttccaggtcaagttggagacccggcagatc
acgtggagtcgaggggcagataaaatcgagggagcggttgatattcgtgaaatcaaggag
atccggcctgggaaaacctctcgtgattttgaccgttaccaggaggacccggccttccgg
cccgaccagtcccattgctttgttatcctgtacggcatggaattccgcctgaaaacgctg
agtctgcaagccacctcggaggacgaagtgaatatgtggatcaaaggcttgaactggttg
gtgactgataccgtgcaggcggccacgcctctgcagatcgagaggtggctccggaagcag
ttctactccgtggatcggaatcgggaagacaggatttctgccaaggatcttaagaacatg
ctgtcccaggtcaactaccgagttcccaacatgcggttcctgagggaacggttgacggac
atggagcagcggagtggggacatcacctatggccagtttgcgcagctctaccgcagcctc
atgttcagtgcccagaaatcgatggactttcctttcctggaagccggcaccctgaggggc
ggggatcgacccgagctctgcagagtttccctgtcggagtttcagcagtttctcctggaa
taccagggggagctgtgggccactgacaggctgcaggtgcaggagttcatgctcagcttc
ctccaagacccgctccgggaaatcgaggagccttacttcttcctggacgagtttgttacc
ttcctgttttccaaagagaataacatctggaactcccagctggattcggtgtgtgtggac
accatgaacaaccctctgtctcagtattggatctcttcatctcacaacacgtacctgacc
ggggaccagttctccagcgagtcctccttggaggcctatgcgcggtgcctccggatgggc
tgccgatgcatcgagttggactgctgggatggaccggacgggatgccagtcatttaccat
ggacacaccctcaccaccaagatcaagttctccgatgttctgcacaccatcaaggagcat
gccttcgtgacctcggagtaccccgtgatcttgtccattgaggatcattgcagcatcgct
cagcagagaaacatggcccagtacttcaagaaggtatttggcgacacgcttctcaccaag
cccgtggacattgcggctgatggtctgccttcgcccaaccagctcaagagaaaaatcctt
atcaagcacaagaagctggctgagggcagtgcctacgaggaggtgcccacgtcggtgatg
tactcagagaatgacatcagcaattccatcaagaacggcatcctctatttggaagacccc
attaatcacgagtggtacccgcactactttgtactgaccagcagcaaaatctattactca
gaggagaccaacagtgaccagggcaacgaggacgaggaggagccaaaggaggtgagcagc
agtgccgagctacactccagcgagaaatggttccatgggaagctaggggccggtcgggac
gggcgacacatcgccgagcggctgcttaccgagtactgcattgagaccggagcccccgac
ggttcctttctggttcgggagagtgagacctttgtcggggactacaccctgtccttctgg
cggaacgggaaggtgcagcactgccggatccactcccgtcaggacgccggcagccccaag
ttcttcctgacagacaacctggtgtttgactcgctctatgacctcatcacccactaccag
caggtgccgctgcgatgcaacgagttcgagatgcgccttacggagcccgtgcctcagact
aacgcacacgagagcaaagagtggtaccacgccagtctgacccgagcccaggcggaacat
atgttgatgcgggttccccgggacggggccttcctcgtgcgaaagcggagcgagcccaac
tcctacgccatctccttccgggcagaagggaagatcaaacattgccgggtccagcaggag
gggcagacggtgatgctggggaactcggagtttgacagccttgtagatctcatcagttac
tatgagaagcatccactgtatcgaaagatgaagctccggtaccccatcaatgaggaggca
ttggagaagatgggcacagcggaacctgactatggagctctgtatgaaggacggaatcca
ggtttctatgtggaggcaaatcctatgccaacttttaagaacggccggggcatcgtgtgt
ccttttgtggagattgaggtggccggggccgactacgacaacatgaagcacaagacggag
tttgtggtggacaatggtctgaaccccgtttggccggcaaagcccttccacttccagatt
agtaaccccgagtttgctttcctgcgctttgtggtatatgaagaagatatgttcagtgac
cagaatttcttggctcaggccaccttcctggtgaaaggcctaaagacaggatacagagcg
gtgcctttgaagaataactacagtgaggacttggagttggcctctctgcttatcaaaata
gatatatttcctgccaagcaggagaacggggagatcagtccctttggcagctcgtcgttc
cgagaacggggctccgaatcttctggccagctgctccacggacgggcccgggagggctcc
tttgaagcccgctaccagcagcccttcgaggacttccgcatctcccaggagcacctagca
gaccactttgacagccgggaacgaagggcacttcggagaactcgtatcaatggagacaac
cgcctctag

DBGET integrated database retrieval system