KEGG   Sarcophilus harrisii (Tasmanian devil): 100923284
Entry
100923284         CDS       T02286                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00140  Steroid hormone biosynthesis
shr01100  Metabolic pathways
shr04913  Ovarian steroidogenesis
shr04925  Aldosterone synthesis and secretion
shr04927  Cortisol synthesis and secretion
shr04934  Cushing syndrome
Module
shr_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:shr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100923284
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100923284
   04925 Aldosterone synthesis and secretion
    100923284
   04927 Cortisol synthesis and secretion
    100923284
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100923284
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:shr00199]
    100923284
Enzymes [BR:shr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     100923284
Cytochrome P450 [BR:shr00199]
 Cytochrome P450, animal type
  CYP11 family
   100923284
SSDB
Motif
Pfam: p450 Cytomega_US3
Other DBs
NCBI-GeneID: 100923284
NCBI-ProteinID: XP_003755019
Ensembl: ENSSHAG00000013344
UniProt: G3WJQ5
Position
2:617798821..617822314
AA seq 524 aa
MFTRGISQQSALAKRCRYLLGSPRQDGWTSNVRRVQLPARDSDLATFPLRDRRPRPFNEI
PLNGANGWLNLFHFWMENGIRNLHIRTLQGFQQLGPIYREKLGNTESVFIINPDDAACLF
KAEGPYPERYCVPPWVAYHTYMKKPIGVLFKNSESWKKDRVFLNQFVMALDSINNFEPLL
TPISEDFVKKIYKEIERSDQGKYTVDLSQDLFRFAFESICNILFGERLGLLEEFVDPEAQ
KFIDAVSTLFDTSVPMLNVPPELFRMVRAKTWRDHVASWDLIFDRAESYVQTFYQDQKMR
SEVTKCYSGILYCLLDKNTMNFEDVKANVTEMMAGGVDTTSMTLQWCLYELSRNLKVQDM
LRAEVLAARRNAQGDVKMMLKSVPLLKAAIKETLRLHPIAITIQRYIPSDLVLQDYTIPA
KTLVQVAIFAMGKDPNFFPNPEKFDPSRWFQENTYFRALSFGFGPRQCLGRRIAELEMTI
FLMHILENFRVEVQKLSDVGTTFNLILMPDKPIVFTFRPFKPQL
NT seq 1575 nt   +upstreamnt  +downstreamnt
atgtttaccaggggaatttcacaacagtcagctctggctaagcgctgtcgttacctcctt
ggttcaccaagacaagatggttggacatctaatgttcggagagttcagctgccagctaga
gatagtgacctggccaccttccctctccgggatcggaggccccggcccttcaacgagata
cccttaaatggagccaatggttggctgaatctgttccacttctggatggagaatgggata
cggaacctgcatatccgaaccttgcagggcttccaacagttaggaccaatttaccgggag
aaacttggcaatacggaatctgtttttatcatcaaccctgatgatgctgcctgcctcttt
aaggcagaaggaccctatccagaaagatactgtgtcccaccatgggtggcttatcacacc
tacatgaaaaaacctattggagtccttttcaagaactctgaaagctggaagaaagatcgg
gttttcctgaaccagtttgtgatggctttggactccatcaacaattttgagccccttctc
accccaatttcagaggactttgtaaagaagatatacaaggagattgagaggagtgaccaa
ggaaagtacactgtggacctcagtcaggacctgtttcgatttgcttttgagtctatctgc
aacattctctttggggagcgtctggggctcctggaagagtttgtggaccctgaggcccag
aagttcattgatgccgtgtcaacactgtttgataccagtgttccgatgctgaatgtccct
ccagaattgttccgcatggtcagggccaagacctggagggaccacgtggcctcgtgggac
ctgatttttgatcgagctgaaagttatgtgcagaccttctaccaggaccagaagatgagg
tcggaagtcactaagtgttactcgggcattctctactgtctcttagacaagaataccatg
aattttgaagatgtcaaagccaatgttaccgagatgatggcaggaggagtagatacgaca
tccatgaccttgcaatggtgcctgtatgaattgtctaggaacctaaaggtacaagatatg
cttcgggctgaagtcctggctgcccgacgaaatgcccagggagatgtgaagatgatgctt
aaatctgttccccttctcaaagccgccatcaaggaaaccctgaggttacaccccattgca
atcaccatacaacggtacattccatcggatttagttctccaggattacaccatccctgct
aaaacactggtccaggtggccatctttgccatggggaaggatcctaacttcttccccaac
ccagaaaagtttgacccctccagatggtttcaagagaatacctacttccgtgctctgagc
tttggttttggccctcggcagtgcctcggacggaggattgccgagttggagatgactatc
tttctgatgcatattctggagaatttcagggtcgaagtccagaagctttcagatgtgggg
accacctttaatctcatcttgatgcctgacaagcccatcgtgttcaccttccggcccttc
aagccccagctgtaa

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