KEGG   Sarcophilus harrisii (Tasmanian devil): 100925013Help
Entry
100925013         CDS       T02286                                 

Gene name
MAPK14
Definition
(RefSeq) mitogen-activated protein kinase 14 isoform X2
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01522  Endocrine resistance
shr04010  MAPK signaling pathway
shr04015  Rap1 signaling pathway
shr04068  FoxO signaling pathway
shr04071  Sphingolipid signaling pathway
shr04218  Cellular senescence
shr04261  Adrenergic signaling in cardiomyocytes
shr04370  VEGF signaling pathway
shr04380  Osteoclast differentiation
shr04550  Signaling pathways regulating pluripotency of stem cells
shr04611  Platelet activation
shr04620  Toll-like receptor signaling pathway
shr04621  NOD-like receptor signaling pathway
shr04622  RIG-I-like receptor signaling pathway
shr04625  C-type lectin receptor signaling pathway
shr04657  IL-17 signaling pathway
shr04658  Th1 and Th2 cell differentiation
shr04659  Th17 cell differentiation
shr04660  T cell receptor signaling pathway
shr04664  Fc epsilon RI signaling pathway
shr04668  TNF signaling pathway
shr04670  Leukocyte transendothelial migration
shr04714  Thermogenesis
shr04722  Neurotrophin signaling pathway
shr04723  Retrograde endocannabinoid signaling
shr04728  Dopaminergic synapse
shr04750  Inflammatory mediator regulation of TRP channels
shr04912  GnRH signaling pathway
shr04914  Progesterone-mediated oocyte maturation
shr04917  Prolactin signaling pathway
shr04926  Relaxin signaling pathway
shr04933  AGE-RAGE signaling pathway in diabetic complications
shr05014  Amyotrophic lateral sclerosis (ALS)
shr05132  Salmonella infection
shr05133  Pertussis
shr05140  Leishmaniasis
shr05142  Chagas disease (American trypanosomiasis)
shr05145  Toxoplasmosis
shr05152  Tuberculosis
shr05160  Hepatitis C
shr05164  Influenza A
shr05167  Kaposi's sarcoma-associated herpesvirus infection
shr05169  Epstein-Barr virus infection
shr05205  Proteoglycans in cancer
shr05418  Fluid shear stress and atherosclerosis
Module
shr_M00689  MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:shr00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100925013 (MAPK14)
   04010 MAPK signaling pathway
    100925013 (MAPK14)
   04370 VEGF signaling pathway
    100925013 (MAPK14)
   04668 TNF signaling pathway
    100925013 (MAPK14)
   04068 FoxO signaling pathway
    100925013 (MAPK14)
   04071 Sphingolipid signaling pathway
    100925013 (MAPK14)
 Cellular Processes
  Cell growth and death
   04218 Cellular senescence
    100925013 (MAPK14)
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100925013 (MAPK14)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100925013 (MAPK14)
   04620 Toll-like receptor signaling pathway
    100925013 (MAPK14)
   04621 NOD-like receptor signaling pathway
    100925013 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    100925013 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    100925013 (MAPK14)
   04660 T cell receptor signaling pathway
    100925013 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    100925013 (MAPK14)
   04659 Th17 cell differentiation
    100925013 (MAPK14)
   04657 IL-17 signaling pathway
    100925013 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    100925013 (MAPK14)
   04670 Leukocyte transendothelial migration
    100925013 (MAPK14)
  Endocrine system
   04912 GnRH signaling pathway
    100925013 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    100925013 (MAPK14)
   04917 Prolactin signaling pathway
    100925013 (MAPK14)
   04926 Relaxin signaling pathway
    100925013 (MAPK14)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100925013 (MAPK14)
  Nervous system
   04728 Dopaminergic synapse
    100925013 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    100925013 (MAPK14)
   04722 Neurotrophin signaling pathway
    100925013 (MAPK14)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100925013 (MAPK14)
  Development
   04380 Osteoclast differentiation
    100925013 (MAPK14)
  Environmental adaptation
   04714 Thermogenesis
    100925013 (MAPK14)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100925013 (MAPK14)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    100925013 (MAPK14)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    100925013 (MAPK14)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100925013 (MAPK14)
  Infectious diseases
   05132 Salmonella infection
    100925013 (MAPK14)
   05133 Pertussis
    100925013 (MAPK14)
   05152 Tuberculosis
    100925013 (MAPK14)
   05164 Influenza A
    100925013 (MAPK14)
   05160 Hepatitis C
    100925013 (MAPK14)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    100925013 (MAPK14)
   05169 Epstein-Barr virus infection
    100925013 (MAPK14)
   05145 Toxoplasmosis
    100925013 (MAPK14)
   05140 Leishmaniasis
    100925013 (MAPK14)
   05142 Chagas disease (American trypanosomiasis)
    100925013 (MAPK14)
  Drug resistance
   01522 Endocrine resistance
    100925013 (MAPK14)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100925013 (MAPK14)
Protein kinases [BR:shr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100925013 (MAPK14)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo APH Haspin_kinase Kinase-like NAD_binding_8
Motif
Other DBs
NCBI-GeneID: 100925013
NCBI-ProteinID: XP_003769046
Ensembl: ENSSHAG00000001726
Position
4
AA seq 360 aa AA seqDB search
MSQERPKFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDKKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHGYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt NT seq  +upstreamnt  +downstreamnt
atgtctcaggagaggcctaagttctaccggcaggagctgaacaagaccatctgggaggtg
cccgagcgctaccagaacctgtccccggtcggctccggagcctatgggtccgtgtgtgct
gcttttgacaaaaaaacaggattacgtgtggcagtgaagaagttatccagaccatttcag
tctatcatccatgcaaaaaggacttatagggagttgcgattacttaagcatatgaaacat
gaaaatgtgattggccttttagatgttttcacacctgcaaaatctctggaggaattcaat
gatgtgtatctggtgacacatctcatgggggcggatctgaacaatattgtgaaatgtcaa
aaactcactgatgaccatgtacaattccttatctaccagattctccggggcttaaagtat
attcattcagctgatattatacacagagacctgaaacctagtaacttagctgtgaatgaa
gactgtgagcttaagatcctagattttggactggcccggcacacagatgatgaaatgaca
ggctatgtggctactaggtggtacagggctcctgaaatcatgctgaactggatgcattac
aaccaaacagttgatatttggtcagtaggatgcataatggcagagctgttgactggaagg
acactgtttccgggtacagaccatattaaccagcttcagcagatcatgcgcctgacgggg
acaccccctgcctatctcattaacaggatgcccagtcatgaggcaagaaattatattcaa
tctttgacccagatgccgaagatgaactttgcaaatgtatttattggtgccaatccattg
gctgtcgatctgctggagaagatgcttgtattggactcggataagagaattacggcagct
caagcccttgcccatggatactttgctcagtaccatgatcctgatgatgaaccagttgca
gacccctatgaccagtcctttgaaagcagggatctcctgatagatgaatggaaaagcctg
acctatgatgaagttattagctttgtgccaccgccactcgaccaagaagagatggagtcc
tga

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