KEGG   Sarcophilus harrisii (Tasmanian devil): 100925455Help
Entry
100925455         CDS       T02286                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100925455 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100925455 (PIK3CG)
   04015 Rap1 signaling pathway
    100925455 (PIK3CG)
   04012 ErbB signaling pathway
    100925455 (PIK3CG)
   04370 VEGF signaling pathway
    100925455 (PIK3CG)
   04630 Jak-STAT signaling pathway
    100925455 (PIK3CG)
   04668 TNF signaling pathway
    100925455 (PIK3CG)
   04066 HIF-1 signaling pathway
    100925455 (PIK3CG)
   04068 FoxO signaling pathway
    100925455 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    100925455 (PIK3CG)
   04024 cAMP signaling pathway
    100925455 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    100925455 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    100925455 (PIK3CG)
   04152 AMPK signaling pathway
    100925455 (PIK3CG)
   04150 mTOR signaling pathway
    100925455 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100925455 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    100925455 (PIK3CG)
  Cellular commiunity
   04510 Focal adhesion
    100925455 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100925455 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    100925455 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    100925455 (PIK3CG)
   04660 T cell receptor signaling pathway
    100925455 (PIK3CG)
   04662 B cell receptor signaling pathway
    100925455 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    100925455 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    100925455 (PIK3CG)
   04670 Leukocyte transendothelial migration
    100925455 (PIK3CG)
   04062 Chemokine signaling pathway
    100925455 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    100925455 (PIK3CG)
   04915 Estrogen signaling pathway
    100925455 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    100925455 (PIK3CG)
   04917 Prolactin signaling pathway
    100925455 (PIK3CG)
   04921 Oxytocin signaling pathway
    100925455 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    100925455 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100925455 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100925455 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100925455 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    100925455 (PIK3CG)
   04722 Neurotrophin signaling pathway
    100925455 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100925455 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    100925455 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100925455 (PIK3CG)
   05205 Proteoglycans in cancer
    100925455 (PIK3CG)
   05203 Viral carcinogenesis
    100925455 (PIK3CG)
   05210 Colorectal cancer
    100925455 (PIK3CG)
   05212 Pancreatic cancer
    100925455 (PIK3CG)
   05214 Glioma
    100925455 (PIK3CG)
   05221 Acute myeloid leukemia
    100925455 (PIK3CG)
   05220 Chronic myeloid leukemia
    100925455 (PIK3CG)
   05218 Melanoma
    100925455 (PIK3CG)
   05211 Renal cell carcinoma
    100925455 (PIK3CG)
   05215 Prostate cancer
    100925455 (PIK3CG)
   05213 Endometrial cancer
    100925455 (PIK3CG)
   05222 Small cell lung cancer
    100925455 (PIK3CG)
   05223 Non-small cell lung cancer
    100925455 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100925455 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100925455 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100925455 (PIK3CG)
   05166 HTLV-I infection
    100925455 (PIK3CG)
   05162 Measles
    100925455 (PIK3CG)
   05164 Influenza A
    100925455 (PIK3CG)
   05161 Hepatitis B
    100925455 (PIK3CG)
   05160 Hepatitis C
    100925455 (PIK3CG)
   05169 Epstein-Barr virus infection
    100925455 (PIK3CG)
   05146 Amoebiasis
    100925455 (PIK3CG)
   05145 Toxoplasmosis
    100925455 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    100925455 (PIK3CG)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100925455 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
5
AA seq 1103 aa AA seqDB search
MDLEDHDPVILREDNRGRRRKMKPQSAGMNLSSMEFIPIEFVLPTTHPLTKVAETVILEA
AGNCSVEQVKAQVWMQAMETSMTMEFYHQSSPEQFLLLYQKKEQWYEIYDKYQLIETLDC
VKYWKAFHKNMGQIHVVQRQPPTEETWAFQKQLNDLIDYDVTDMSNVHDDELEFTRRRLV
TPRIMEVASRDPKLYAMHPWITSKPLPTYLLKKIVNNCILIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQNELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDTPPDPGQDEVRKEDWPLVDDCTGVTGYHEQLTINGKNHERVFTLSLWDCDRRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFDIKIK
DLPKGALLNLQIYCGKAPSQSSKAAGSHEISSFEAKGKTQLLYYVNLLLIDHRYLLRHGE
YVLHMWKISGKGENQGSMNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPE
GDRVRGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWG
QQEIVAKTYQLLARREAWDQSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEA
YLRGCGMAMLEDFTKQVQVIRLLQKVTIEIKSLSAEKYDVTSQVISQLKQKLENLQNSNL
PKSFRVPYDPGLRAGILMIEKCKVMASKKKPLWLEFKCADPTAQSNETIGIIFKHGDDLR
QDMLILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDAITIAKIQQSTVGNT
GAFKDEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGN
LFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDICAKAYLA
LRKHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKG
WTVQFNWFLHLVLGIKQGEKHSA
NT seq 3312 nt NT seq  +upstreamnt  +downstreamnt
atggatttggaggaccatgatcctgtgattctgagagaagataacagggggagaaggcgg
aaaatgaaaccacaaagtgctggtatgaacttatcatcaatggaattcattcctatagaa
tttgtcctgcccaccacccacccactcaccaaagtcgctgaaacagtgatcctggaagca
gctggaaattgcagtgtggagcaggtgaaggcacaggtctggatgcaggccatggagact
agtatgaccatggaattctatcaccaatcatccccagaacaatttctcctgctgtaccag
aaaaaggaacagtggtatgagatctatgacaagtaccaattgatagagacattggactgt
gtgaagtactggaaagccttccataagaacatgggtcagattcatgtggtccagaggcag
ccacccacagaggaaacatgggcattccagaagcagctaaatgatctgattgactatgat
gtcactgatatgagcaatgtgcacgatgatgagttggaattcacccggcgccggcttgtc
actccacggatcatggaggtggccagccgagaccccaaactctatgccatgcatccctgg
atcacttccaagccactccccacatatttgttgaaaaagattgtcaataattgcattttg
attgtcatccaccgaagtaccacaagtcagacaatcaaggtctctgcagatgacacccca
ggtacaatcttacagagcttcttcaccaagatggctaagaagaagtcactaatggacatc
cctgaaagtcaaaatgagctggattttgtgcttcgggtctgtggccgggatgagtacatt
gtgggtgaaacgccaatcaagaatttccagtggatcaggcattgtctcaagaatggggag
gagattcaccttgtgctggatactcctcctgacccagggcaggatgaagtgaggaaggag
gattggccacttgtagatgactgtacaggagtcacaggctaccatgagcagctcacaata
aatggcaagaatcatgagagagtgtttactctttccctatgggactgtgatcgaaggttt
agggtcaagatcaggggcattgacatccctgtgctcccacggaacacggagctaacggtc
tttgtggaagcaaacatccaacatggacagcaggtcctttgccaaaggcgaaccacctct
aaacctttcacagaggaggtgctctggaatgtgtggcttgagtttgatatcaaaatcaag
gacctgcccaaaggggctttactgaaccttcagatttactgtgggaaagcaccatcccag
tcttccaaggctgctggatctcatgagatttctagctttgaagccaaaggcaaaactcaa
ttactctattatgtgaatctactgttaatagaccaccgatatctcttgaggcatggagaa
tatgtccttcacatgtggaagatatcagggaagggagagaaccaaggaagcatgaatgcc
gataagcttacatcagcaaccaaccctgataaggagaattctatgtcaatctccattctg
ctggacaattattgccaccccatagccttgcctaagcacaggcccacgcctgaccctgaa
ggggacagggtacggggagaaatgccaaatcagcttcgaaaacagctagaagagatcata
gccactgacccacttaacccactgactgcaaaggacaaagaattactatggcattttagg
tatgaaagccttaagcatcccaaagcgtatcctaagctatttagctcagtgaagtggggg
caacaagaaattgtggccaaaacataccagttgttagccagaagagaagcttgggatcaa
agtgatttggatgttgggttaacaatgcaactcctggactgcaacttttcagatgaaaat
gtaagagccattgcagttcaaaagctagaaagcttggaggatgatgatgtcttgcattac
ctgctgcaactagttcaggctgtgaaatttgaaccataccatgacagtgctcttgccaga
tttctgctgaaacgtggtttgagaaacaagagaatcggtcatttcttgttttggtttcta
agaagtgagattgctcagtccagacattaccagcaacgatttgcagtgatcctcgaagcc
tatctgaggggctgcggcatggccatgttagaggatttcacaaaacaagttcaagtaatc
aggttgctacaaaaagtcactattgagattaagtcactgtctgctgaaaagtacgatgtc
acttcccaagttatttcgcaacttaaacaaaagcttgaaaaccttcagaattctaatctt
ccaaaaagttttagagttccctatgatcctggcctgagagctggaatactcatgattgaa
aagtgcaaagtaatggcgtccaagaagaagcctttatggcttgaatttaaatgtgctgat
cccacagcccagtccaatgaaacaataggaattatttttaaacatggagatgatttgcgt
caagacatgcttattttacaaattcttcgaattatgggatctatttgggaagcagaatct
ttggacttgtgcctgcagccatatggttgcatttcaactggagacaaaataggaatgatt
gaaattgtgaaggatgctataacaattgccaaaattcagcagagcacagtgggcaatact
ggagcattcaaggatgaggtgctaaatcattggctcaaagaaaaatgcccaattgaagaa
aagttccaggcagcagtggagaaatttgtgtattcatgtgccggctattgtgtggcaact
tttgttcttggtataggagacagacacaatgacaacattatgatcacagagacaggaaat
ctatttcatattgactttggtcacattcttgggaattacaaaagttttctgggtatcaac
aaagagagagttccatttgtgctaaccccagacttcctcttcgtgatgggaacttctgga
aagaaaacaagcctgcacttccagaaatttcaggacatttgtgccaaggcttacctagct
cttcgaaaacacactaacctgctgatcatcctgttttccatgatgttgatgactggaatg
ccacagttaactagcaaggaagatattgagtatatccgggatgccttgacagtggggaaa
aatgaagaagaggccaaaaagtatttccttgatcagatagaagtttgtagagacaaaggt
tggactgtacagttcaattggttcttacatcttgttcttggtatcaaacaaggagaaaaa
cactctgcctag

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