KEGG   Sarcophilus harrisii (Tasmanian devil): 100926139Help
Entry
100926139         CDS       T02286                                 

Gene name
PRKAA2
Definition
protein kinase, AMP-activated, alpha 2 catalytic subunit
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:shr00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    100926139 (PRKAA2)
   04151 PI3K-Akt signaling pathway
    100926139 (PRKAA2)
   04152 AMPK signaling pathway
    100926139 (PRKAA2)
   04150 mTOR signaling pathway
    100926139 (PRKAA2)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    100926139 (PRKAA2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100926139 (PRKAA2)
   04920 Adipocytokine signaling pathway
    100926139 (PRKAA2)
   04921 Oxytocin signaling pathway
    100926139 (PRKAA2)
  Environmental adaptation
   04710 Circadian rhythm
    100926139 (PRKAA2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100926139 (PRKAA2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100926139 (PRKAA2)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100926139 (PRKAA2)
Protein kinases [BR:shr01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   100926139 (PRKAA2)
Mitochondrial biogenesis [BR:shr03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100926139 (PRKAA2)
  Mitophagy factors
   Other mitophagy factors
    100926139 (PRKAA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
4
AA seq 610 aa AA seqDB search
MATNVATLVSRSEGLCGGVDITYRSLAGLCSTLRQDPAELAFLGMVSGILSKVKLRRAVV
ESPAEYQKLIHVSPCKKQLLVCCIQSKNSTIGEHQLTGHKVAVKILNRQKIRSLDVVGKI
KREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEETEARRLFQ
QILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA
PEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSI
ATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFE
CTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDSAMHIPV
GLKPHPERMPPLVSDSPKAKCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMNEVYR
AMKQLDYEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYQVDNRSYLLDFKSIDDDLAEQKS
GSSTPQRSCSAAGLHRPRLSFDSTTADCHSLAGSLTGSLTGSVPSVAPRLGSHTMDFFEM
CASLITTLAR
NT seq 1833 nt NT seq  +upstreamnt  +downstreamnt
atggcaaccaacgtggcaactctggtgtccaggtcagaagggctctgtggtggtgtggac
attacctaccgctccttggccggcctgtgctccacgctgcggcaggacccagccgagctc
gctttcttgggcatggtctctggcatccttagtaaagtaaagctgaggagggctgtagtg
gagtcacctgctgaataccagaaactcattcatgtttctccctgcaagaagcagctcctt
gtttgctgtattcagagcaagaactcaacaattggagaacaccagttgacaggccataaa
gtggcagtcaaaatcttaaatagacagaagattcgtagtttggatgtggttggaaaaatc
aaacgagagattcaaaatctaaaactcttccgacatccccacattatcaaactataccaa
gtcatcagcaccccaactgatttttttatggtaatggaatatgtgtctggtggtgaatta
tttgactacatctgtaaacatggacgggttgaagagacagaggctagaagactctttcag
cagattctttctgctgtggattattgtcacagacacatggttgttcaccgagacctgaaa
cccgagaatgtgctgctggatgcccacatgaatgccaagattgccgactttggtttatca
aatatgatgtcagatggtgaatttctgagaacgagctgtgggtctccaaattatgcagca
cctgaagtcatctcaggcaggttgtacgcggggcccgaggtggacatctggagctgcggc
gtgatcctgtacgccctgctctgcgggacgctgcccttcgatgatgagcacgtccccacc
ttgtttaagaagatccgcgggggggtcttctacatcccggagtacctgaaccgttccatc
gccactctgctcatgcacatgctgcaggtggaccctctgaaacgggccaccatcaaggac
atcagagaacacgagtggtttaaacaagacttacccagttatttatttcctgaagaccct
tcctatgatgcaaatgtcattgatgatgaagctgtgaaggaagtgtgtgaaaagtttgag
tgcacagagtccgaagtgatgaacagcctgtacagcggagacccccaggaccagctcgcc
gtggcttaccacctcatcatcgacaaccggcgcatcatgaaccaggccagcgagttctac
ctggcctccagcccgcccacgggctccttcatggacgacagcgccatgcacattcccgtc
gggctgaagccgcaccccgagcgcatgccgcccctcgtctccgacagccccaaagccaag
tgccccctggacgccctgaacacgaccaagcccaagtctctggctgtgaaaaaggccaag
tggcacctgggcatccgcagtcagagcaaaccctacgatattatgaatgaggtctaccgg
gccatgaagcagctggattatgaatggaaggtggtaaatgcttatcatcttagagtgaga
aggaagaaccctgtgaccggcaattatgtgaaaatgagccttcagctgtaccaggtggac
aatcgaagttaccttttggacttcaagagtattgacgatgacctggcggagcagaagtcc
ggctcctccacgccccagcgctcctgctctgctgccggcctacaccgaccaaggctgagc
ttcgattcgaccacggccgactgccattctctcgctggatccttgacgggctccctgacg
gggagtgtgccttcggtagcgccgcgcctgggcagccacaccatggactttttcgaaatg
tgcgccagtctgatcactaccttagctcgctga

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