KEGG   Sarcophilus harrisii (Tasmanian devil): 100929015Help
Entry
100929015         CDS       T02286                                 

Gene name
PLCB2
Definition
phospholipase C, beta 2
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100929015 (PLCB2)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100929015 (PLCB2)
   04310 Wnt signaling pathway
    100929015 (PLCB2)
   04020 Calcium signaling pathway
    100929015 (PLCB2)
   04070 Phosphatidylinositol signaling system
    100929015 (PLCB2)
   04022 cGMP - PKG signaling pathway
    100929015 (PLCB2)
 Cellular Processes
  Cell communication
   04540 Gap junction
    100929015 (PLCB2)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100929015 (PLCB2)
   04062 Chemokine signaling pathway
    100929015 (PLCB2)
  Endocrine system
   04911 Insulin secretion
    100929015 (PLCB2)
   04912 GnRH signaling pathway
    100929015 (PLCB2)
   04915 Estrogen signaling pathway
    100929015 (PLCB2)
   04921 Oxytocin signaling pathway
    100929015 (PLCB2)
   04918 Thyroid hormone synthesis
    100929015 (PLCB2)
   04919 Thyroid hormone signaling pathway
    100929015 (PLCB2)
   04916 Melanogenesis
    100929015 (PLCB2)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100929015 (PLCB2)
   04270 Vascular smooth muscle contraction
    100929015 (PLCB2)
  Digestive system
   04970 Salivary secretion
    100929015 (PLCB2)
   04971 Gastric acid secretion
    100929015 (PLCB2)
   04972 Pancreatic secretion
    100929015 (PLCB2)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100929015 (PLCB2)
  Nervous system
   04724 Glutamatergic synapse
    100929015 (PLCB2)
   04725 Cholinergic synapse
    100929015 (PLCB2)
   04728 Dopaminergic synapse
    100929015 (PLCB2)
   04726 Serotonergic synapse
    100929015 (PLCB2)
   04720 Long-term potentiation
    100929015 (PLCB2)
   04730 Long-term depression
    100929015 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    100929015 (PLCB2)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100929015 (PLCB2)
  Environmental adaptation
   04713 Circadian entrainment
    100929015 (PLCB2)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100929015 (PLCB2)
   05016 Huntington's disease
    100929015 (PLCB2)
  Infectious diseases
   05146 Amoebiasis
    100929015 (PLCB2)
   05142 Chagas disease (American trypanosomiasis)
    100929015 (PLCB2)
   05143 African trypanosomiasis
    100929015 (PLCB2)
Enzymes [BR:shr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100929015 (PLCB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 1184 aa AA seqDB search
MSLLSPILLPPEVKSYLTRGERFIKWDDETSVASPVILRVDPNGYYLYWTYQSKEMEFLD
ITSIRDTRFGKFAKMPKTQKLREVFNLDFPDNTFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVSKDWAEDVLALAKNPLTANAPRSKFLNKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALSACHLPKGKNDSINPEDFPEPVYRSFLMNLCPRPEIDEIFTSHHSKAKPYMTKDH
LTKFINQKQRDARLNSLLFPPARPDQVQCLIEKYEPSGINIQRGQLSPEGMVWFLSGPEN
SIVAHDKLILHQDMSQPLNHYFINSSHNTYLTAGQFSGPSSSEMYRQVLLSGCRCVELDC
WKGKPPEEEPIITHGFTMTTDILFKDAVEAIAESAFKTSLYPVILSFENHVDSPRQQAKM
AEYCRTIFGDMLLTEPLDKFPLKPGIPLPSPQDLLGKILIKNKKNQSPGPISPKKELCAE
TEDFNQTNPALGEDTVWVGEEEAELEEEEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEE
MSSLVNYIQPTKFISFEFSSQKNRSYVISSFTELKAYDLLTKSPVQFVDYNKRQMSRIYP
KGTRMDSSNYSPQMFWNAGCQMVALNFQTMDMPMQQNMALFEFNGQSGYLLKHEFMRRPD
KQFDPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVEVFGLPGDPKRRYRTKLTPN
ANSINPVWKEDPFVFEKIMMPELASLRVAVLEEGGKFIGHRIIPVHALQSGYHHLCLRSE
SNIPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFNAQDKKSVKLQDTGDDPPDRLL
PLRNSALGQANGTLISAGSSMAPSPNGPAAAVTWFKEEAMKEAAEPQTASLEELQQLKGF
LKLQKRQEKELRELERRGVRRWEELLQKYACLQSELTTQGGCRKLSVTKGSRKKRNLPWE
DTREAGQGPMEGPESIDGRIRELKEKLETELYQQGEEQYESIMKRKEQHGTEQIAKVMEL
AQERQAVELKALKESAESNTKEMKKKLEVKRLERIQAMSKITSDKMAQERLKREINNSHI
QEVVHIIKQMTETLERHQERLEEKQAACLEQIREKEKKFQQEALSEYEEQMKGLEAKVKE
AVRCCLSFPQDDQDKKLEIPSVVEEPSEETSCPNEASSQLDSRL
NT seq 3555 nt NT seq  +upstreamnt  +downstreamnt
atgtctttgctcagcccaatcctgctgccccctgaggtgaagagctatctaacccgagga
gagcgcttcatcaaatgggatgatgagacttctgtggcatctccagtcatcctccgagtg
gatcccaatggctattacttgtactggacatatcaaagcaaggagatggagttcctggac
atcaccagtattcgggatactcgttttgggaagtttgctaagatgcccaagacccagaag
cttcgggaggtattcaacttggacttccctgacaacaccttcttgctgaagacgctgact
gttgtgtctggcccagatatggtagacctgaccttccataactttgtctcctacaaagag
aatgtcagtaaggattgggctgaagatgttctggccttggctaaaaacccattaacagcc
aatgccccccggagcaagttcctgaataagatcctagtaaagctcaagatgcagctcaat
ccagaaggaaagatccctgtaaagaattttttccagatgtttcctgctgaccggaaacga
gtagaggctgctctcagtgcctgtcaccttcccaagggcaaaaatgattccatcaaccct
gaggatttccctgaacctgtctacaggagttttctcatgaatctatgtccacgacctgaa
attgatgaaatctttacttctcatcattccaaagcaaagccttacatgaccaaggaccat
ctgaccaagttcattaaccaaaagcagcgggatgcccggctcaactccttactcttccca
ccagcccgacctgaccaagtacaatgcctcattgaaaagtatgagcctagtggcatcaac
atccagaggggtcaactctcaccagagggcatggtttggttcttgagtggtcctgagaac
agcatagtagcccacgacaagctgatactgcaccaggacatgagccagcctctgaatcac
tacttcatcaattcctcccacaacacctacctgacagctggtcagttctcaggaccctca
tcctcagagatgtacagacaggtcttgctctctggctgccgctgcgtggagcttgactgc
tggaagggaaagcctcctgaggaagagccaatcatcacccatggcttcaccatgaccaca
gatattttatttaaggatgcagtagaggctattgctgagagtgccttcaagacctcactc
taccctgtcattctgtcctttgaaaaccatgtagattcgccccgacaacaggccaaaatg
gcagagtactgtcggaccatatttggggacatgctcctcactgagcccctggataagttc
cctttgaagccaggaatccccctccccagtcctcaggaccttctgggtaagatccttatc
aagaataagaagaatcaatccccaggtcccatttcacccaagaaggaattgtgtgcagag
acagaggacttcaaccagactaatccagccttgggtgaggacacagtatgggtaggtgaa
gaagaagctgagttagaggaagaagaagaggaagaatcaggtaacttggatgaagaggaa
ataaagaagatgcaatctgatgagggcacagctggcctggaggtgacagcctatgaagag
atgtctagtctggtcaactatatccaacctaccaagttcatttctttcgagttctcctct
cagaagaatcggagttatgtcatctcttccttcacggagctgaaagcttatgacctgctc
accaagtccccggtgcagtttgtggactacaataagcgccaaatgagtcggatctaccct
aagggtacccgaatggactcatctaactactctccccagatgttctggaatgcaggctgt
caaatggttgccctcaatttccagactatggatatgcctatgcagcagaacatggcactg
tttgagttcaatggacagagtggctaccttctcaagcatgagttcatgcgccgaccagac
aagcaattcgaccctttctctgtggaccgcatcgatgtggtggtggccacaactctctcc
attacggtgatttctggtcagtttctgtcagaacgaagtgtccgaacttatgtggaggtg
gaggtgtttggcttgcctggagaccccaaaagacgttaccgcaccaaactgacacccaat
gccaattccataaatcccgtctggaaagaggacccctttgtctttgaaaagatcatgatg
ccagaactggcctctctgagagtggcagtactggaggaaggaggcaaattcattgggcac
cgaattatccctgtccatgccctgcagtcaggataccaccacttgtgcctcaggagcgag
agcaacattcccctcactatgcctgcactctttgttttcctggaaatgaaagactatgtg
cctgatacctgggcagatctgactgtggctcttgccaaccccatcaaattcttcaatgca
caagacaagaaatcagtaaagctgcaggacactggggatgacccccctgacaggcttttg
ccactcagaaactctgctctgggccaggccaatgggaccctcatctctgcaggttcctct
atggccccatcacccaatggtcctgcagcagctgtgacctggttcaaggaagaagcaatg
aaagaggcggcagaacctcagacagccagcctggaggagctacagcagttgaaagggttc
ctgaagcttcagaaaagacaggaaaaggagcttcgggaactggaaagacggggagtccgg
cgctgggaagaactcctgcaaaaatatgcctgcttacagtctgaactgaccacccaaggt
ggatgcaggaagttgtctgtcacaaagggatcccggaagaagagaaacttgccttgggag
gacacccgtgaggctgggcaggggccaatggaggggccagaaagtatagatggacgtatt
cgagagctgaaggagaagctggagacagaattgtaccagcaaggagaggagcagtatgaa
agcatcatgaaacgcaaggaacagcatggcacagagcaaatcgccaaagtgatggagctg
gcccaggagagacaagctgttgagcttaaagctctcaaggagtctgcagaaagcaacacc
aaagaaatgaagaagaagcttgaagtcaaaaggctagaacggattcaggccatgagcaag
atcaccagtgacaagatggcccaggagagactgaagagagaaattaacaactcacatata
caggaagtggttcacatcatcaaacagatgacagagaccctggagagacaccaggagagg
ctggaagaaaaacaggcagcttgcttggagcagattagggagaaggagaaaaagttccag
caagaggcactgtctgaatatgaggagcagatgaagggcctggaagctaaggtgaaggag
gcggtgagatgctgcctcagtttcccccaagatgaccaagacaagaagctggagatcccc
agtgttgtagaggaaccttcagaggagacatcttgcccaaacgaagcttcttcccagcta
gatagccgtctctaa

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