KEGG   Sarcophilus harrisii (Tasmanian devil): 100931009Help
Entry
100931009         CDS       T02286                                 

Gene name
SOS1
Definition
(RefSeq) son of sevenless homolog 1 isoform X2
  KO
K03099  son of sevenless
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521  EGFR tyrosine kinase inhibitor resistance
shr01522  Endocrine resistance
shr04010  MAPK signaling pathway
shr04012  ErbB signaling pathway
shr04014  Ras signaling pathway
shr04062  Chemokine signaling pathway
shr04068  FoxO signaling pathway
shr04072  Phospholipase D signaling pathway
shr04150  mTOR signaling pathway
shr04151  PI3K-Akt signaling pathway
shr04510  Focal adhesion
shr04540  Gap junction
shr04630  Jak-STAT signaling pathway
shr04650  Natural killer cell mediated cytotoxicity
shr04660  T cell receptor signaling pathway
shr04662  B cell receptor signaling pathway
shr04664  Fc epsilon RI signaling pathway
shr04714  Thermogenesis
shr04722  Neurotrophin signaling pathway
shr04810  Regulation of actin cytoskeleton
shr04910  Insulin signaling pathway
shr04912  GnRH signaling pathway
shr04915  Estrogen signaling pathway
shr04917  Prolactin signaling pathway
shr04926  Relaxin signaling pathway
shr05034  Alcoholism
shr05160  Hepatitis C
shr05165  Human papillomavirus infection
shr05200  Pathways in cancer
shr05205  Proteoglycans in cancer
shr05206  MicroRNAs in cancer
shr05210  Colorectal cancer
shr05211  Renal cell carcinoma
shr05213  Endometrial cancer
shr05214  Glioma
shr05215  Prostate cancer
shr05220  Chronic myeloid leukemia
shr05221  Acute myeloid leukemia
shr05223  Non-small cell lung cancer
shr05224  Breast cancer
shr05225  Hepatocellular carcinoma
shr05226  Gastric cancer
shr05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:shr00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100931009 (SOS1)
   04010 MAPK signaling pathway
    100931009 (SOS1)
   04012 ErbB signaling pathway
    100931009 (SOS1)
   04630 Jak-STAT signaling pathway
    100931009 (SOS1)
   04068 FoxO signaling pathway
    100931009 (SOS1)
   04072 Phospholipase D signaling pathway
    100931009 (SOS1)
   04151 PI3K-Akt signaling pathway
    100931009 (SOS1)
   04150 mTOR signaling pathway
    100931009 (SOS1)
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    100931009 (SOS1)
   04540 Gap junction
    100931009 (SOS1)
  Cell motility
   04810 Regulation of actin cytoskeleton
    100931009 (SOS1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100931009 (SOS1)
   04660 T cell receptor signaling pathway
    100931009 (SOS1)
   04662 B cell receptor signaling pathway
    100931009 (SOS1)
   04664 Fc epsilon RI signaling pathway
    100931009 (SOS1)
   04062 Chemokine signaling pathway
    100931009 (SOS1)
  Endocrine system
   04910 Insulin signaling pathway
    100931009 (SOS1)
   04912 GnRH signaling pathway
    100931009 (SOS1)
   04915 Estrogen signaling pathway
    100931009 (SOS1)
   04917 Prolactin signaling pathway
    100931009 (SOS1)
   04926 Relaxin signaling pathway
    100931009 (SOS1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100931009 (SOS1)
  Environmental adaptation
   04714 Thermogenesis
    100931009 (SOS1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100931009 (SOS1)
   05231 Choline metabolism in cancer
    100931009 (SOS1)
   05206 MicroRNAs in cancer
    100931009 (SOS1)
   05205 Proteoglycans in cancer
    100931009 (SOS1)
   05210 Colorectal cancer
    100931009 (SOS1)
   05225 Hepatocellular carcinoma
    100931009 (SOS1)
   05226 Gastric cancer
    100931009 (SOS1)
   05214 Glioma
    100931009 (SOS1)
   05221 Acute myeloid leukemia
    100931009 (SOS1)
   05220 Chronic myeloid leukemia
    100931009 (SOS1)
   05211 Renal cell carcinoma
    100931009 (SOS1)
   05215 Prostate cancer
    100931009 (SOS1)
   05213 Endometrial cancer
    100931009 (SOS1)
   05224 Breast cancer
    100931009 (SOS1)
   05223 Non-small cell lung cancer
    100931009 (SOS1)
  Substance dependence
   05034 Alcoholism
    100931009 (SOS1)
  Infectious diseases
   05160 Hepatitis C
    100931009 (SOS1)
   05165 Human papillomavirus infection
    100931009 (SOS1)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    100931009 (SOS1)
   01522 Endocrine resistance
    100931009 (SOS1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: RasGEF RasGEF_N RhoGEF Histone PH PH_10 IQ_SEC7_PH PH_13
Motif
Other DBs
NCBI-GeneID: 100931009
NCBI-ProteinID: XP_003758384
Ensembl: ENSSHAG00000014797
UniProt: G3WPQ9
Position
1
AA seq 1316 aa AA seqDB search
MQALQLQYEFFSEENAPKWRGLLVTALKKVQMQVHPTLASNEDALQYVEELILQLLSMLC
QAQPRSVLDVEDRVQKSFPHPIDKWAIADAQSANEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKGFMAEVRQYIRELNLIIKVFREPFVSNSKLFSSH
DVENIFSRIADVHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAQ
DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSSDLYRFAEPDSEENIVFEENMQPKSGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADK
IAMENGDQPLSVELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDTDLLQRLEEFIGT
VRGKAMKKWVESITKIIQRKKMARDNGPGHNITFESSPPAVEWHISRPGHTETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
EAENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESAASAP
NSPRTPLTPPPASGASSTTDVGSVFDSEHSSPFHSRSASVSSINLTKSIDEMPIPPPVPP
RRRPESAPAESSPSKIMPKHLDSPPAIPPRQPTSKVYSPRYSDRTSISDPPESPPLLPPR
EPVRTPDVFSSSPLHLQPPPLGKKSEHGNTFFPNSPSPFTPPPPQTPSPHGTRRHLPSPP
LTQDVDLHSIPAPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq 3951 nt NT seq  +upstreamnt  +downstreamnt
atgcaggcgctgcagctccagtacgagttcttcagcgaggaaaacgcgcccaagtggagg
gggctgctggtgacggccctgaaaaaggtccagatgcaagtccatcctacacttgcttca
aatgaggatgctctccagtatgttgaagagttaattttacagttgttaagtatgctgtgc
caagctcaaccccgaagcgttttagatgttgaggatcgtgtacaaaaaagttttcctcat
ccaattgataagtgggcgatagctgatgctcaatccgctaatgaaaagaggaagcgaaga
aatccattatctctcccagtagaaaaaattcaccctttattaaaggaagttctaggatat
aaaattgaccaccaggtttctgtttacatagtggcagtattagaatacatttctgcagat
attttaaagctggttggaaattatgtacggaatatacgacattatgaaattacaaaacag
gacatcaaagtagcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagaaccttccacttcaggggaacaaacg
tactatgacttggtaaaaggattcatggctgaagttcgacaatatataagggaacttaat
ctcattattaaagtttttagagaaccatttgtctccaattcaaaattattttcttctcac
gatgtagaaaatatatttagtcgtatagcagatgttcatgaactcagtgtaaaattattg
ggccatatagaagacactgtagaaatgacagatgaaggcagtccccatccattagttggt
agctgctttgaagacttagcagaggaattggcatttgatccatatgaatcatatgctcaa
gacatattgcgacctggttttcatgatcactttcttagtcagttatccaagcctggggca
gccctctacttgcagtcaataggtgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagctcctgtgtaccactgtctacattactttgaacttttaaagcagtta
gaagagaagagtgaagaccaagaagacaaagaatgtttgaaacaagcaataacggctttg
cttaaccttcagagcagtatggaaagaatatgttccaaaagtcttgcaaaacggagattg
agcgaatctgcatgtcgattttatagccaacagatgaagggaaaacaactagcaataaag
aaaatgaatgagattcagaagaacattgatgggtgggagggaaaagacattggacagtgt
tgcaatgagtttatcatggaaggaactctcacacgtgtaggtgccaaacatgagagacac
atatttctctttgatggtctgatgatttgctgtaaatcaaatcatggtcagccaagactt
cctggtgctagcaatgctgagtatcgtctcaaagagaagttttttatgcgcaaggtacaa
atcaatgataaggatgacactaatgaatacaaacatgcctttgaaataatcttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaggagaaaaacaactggatggcagca
ctgatatcattacaatatcgtagtactctggaaaggatgctggatgtaacaatgttacaa
gaggagaaggaagagcagatgaggcttccaagttcagatctttatagatttgcagaacca
gattctgaagaaaacatagtatttgaagaaaacatgcaacccaaatctggaattccaatc
atcaaagcaggaaccgttatcaaacttatagagcgactcacctaccatatgtatgctgat
cccaattttgttcggacatttcttacaacatatagatctttctgcaagcctcaagagcta
ctgagtcttctaatagagaggtttgaaattccagagccagagccaacagaagctgataag
atagctatggagaatggagatcaacccctgagtgtggaactaaaacgatttagaaaagaa
tatatacaacccgtacaacttcgagtactaaatgtatgtcggcattgggtagaacatcac
ttctatgattttgaaagggatacagatcttttgcaacgactggaagaatttattggaaca
gtaaggggcaaagcaatgaagaaatgggttgaatctatcactaaaatcattcaacggaaa
aaaatggcaagagacaatggaccaggacataatattacatttgaaagttcaccacctgca
gttgaatggcatataagcagacctggacacacagaaacttttgatctgctcaccttgcac
ccaatagaaattgctcgacagctcactttacttgagtcagatctctacagagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaac
cttctgaaaatgattcgccacacaactaatcttactttgtggtttgaaaagtgtattgta
gaagcagaaaacctagaggaaagagtagctgtggtgagccgaataattgagattcttcaa
gtctttcaagaactgaacaactttaatggtgtacttgaggttgtcagtgccatgaattca
tcacctgtttatagactggaccacacgtttgagcaaattccaagtcgccaaaagaaaatt
ctagaggaagctcatgaactgagtgaagatcactataaaaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttgggatttatttgacaaatatcttgaaaacg
gaagaaggcaatcctgaggttttgaaaagacatggaaaagaactcataaactttagcaaa
agaagaaaagttgcagaaataacaggagagatacagcagtaccaaaatcaaccatattgt
ttgcgagtagaatctgatatcaaaagattctttgaaaatttgaatccaatgggaaatagc
atggaaaaagaattcacagattatcttttcaacaagtcactggaaattgaaccaagaaac
cctaagcctctaccgagatttccaaaaaaatatagttatcccctcaagtctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacaccccacaccactgcagcaggaacca
aggaagatcagttacagccgcatccctgaaagtgaaacagaaagtgcagcatcagcacct
aattctccacggaccccgttaacacctcctccagcttctggtgcttccagtaccactgat
gtgggcagcgtgtttgattctgagcattcaagcccttttcactcaagatctgcttcagta
tcctcaataaatttaactaagagcattgatgaaatgcccatccccccaccagtgccccca
agaagacgaccagaatccgctccagcagaatcttctccctcaaagattatgcccaaacat
ttggatagtcctccagcaattcctcctcggcaacccacatcaaaagtctattcaccacgt
tactccgaccggacctcgatctctgatcctccagaaagccctccccttttaccaccacga
gaacctgtgaggacacctgatgttttctccagctcaccactacatctccagccaccccct
ttgggcaaaaaaagtgaacatggcaatacttttttcccaaacagcccctccccctttacc
ccaccacctcctcaaacaccttctcctcacggcacaaggaggcacctaccatcaccacca
ttaacacaagatgtggaccttcattccatccctgcgcctcctgttcctccacggcaaagc
acttctcaacacatcccaaaacttcctccaaaaacttataaaagggaacacacacaccct
tccatgcatagagatggaccacctttgttggagaatgcccattcctcctga

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