KEGG   Streptococcus ilei I-P16: N597_03805
Entry
N597_03805        CDS       T02880                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sip  Streptococcus ilei I-P16
Pathway
sip00290  Valine, leucine and isoleucine biosynthesis
sip00620  Pyruvate metabolism
sip01100  Metabolic pathways
sip01110  Biosynthesis of secondary metabolites
sip01210  2-Oxocarboxylic acid metabolism
sip01230  Biosynthesis of amino acids
Module
sip_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sip00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    N597_03805
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    N597_03805
Enzymes [BR:sip01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     N597_03805
SSDB
Motif
Pfam: HMGL-like LeuA_dimer DUF6387 VASP_tetra
Other DBs
NCBI-ProteinID: AGY38080
UniProt: U5P3K4
Position
733923..735485
AA seq 520 aa
MRKVEFLDTSLRDGEQTPGVNFSIKEKIAIAKQLEKWGISAIEAGFPAASPDSFTAVQEI
AKVLTKTAVTGLARSVKSDIDACYEALKDAKYPQVHVFIATSPIHREFKLNKTKEEILEA
IKEHVSYARSKFEIVEFSPEDATRTELDFLLQVVQTAVDAGASYINIPDTVGFTTPAEYG
AIFKYLIDHVKTDREIIYSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIGERAGNAAL
EEVAVALNIREDYYQVDSPIVLNETINTSELVSRYSGIPIPKNKAVVGGNAFSHESGIHQ
DGVLKNPLTYEIITPELVGVKSNSLPLGKLSGRHAFVEKLHELGLEFTEEDIKPLFAKFK
SLADKKHEITDADIRALVAGTAVENPEGFHFDDLRLTTNEDESITATVSLKNEDGEILEY
LAKGQGSVEAIFNAIDQFFHQEVRLTSYSIDAVTDGIDAQARVLVTVENEATDTIFNASG
LDFDVLKASAIAYINANTLVQKENAGEIGHIVSYRDLPDA
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgcgtaaagttgaatttttagataccagtcttcgggatggagaacagactcctggagtc
aatttctccattaaagaaaagattgccattgccaagcaattagaaaaatggggaatttct
gctattgaagctggttttccagcagccagtcccgactctttcaccgctgtgcaggaaatt
gcaaaggtcttgaccaagacagctgttacaggtttggctcgctcggtcaaatcggatatt
gatgcctgctatgaagccttgaaagatgcgaagtatccgcaagttcacgtctttatcgca
accagtccgattcaccgggagtttaaactcaacaaaaccaaggaagaaattcttgaagct
atcaaagagcatgtgtcatacgcacgctctaagtttgagattgtggagttctcgccggaa
gatgcaacccggacggaattggatttcctcttgcaagtcgttcaaactgcagtcgatgca
ggggctagctatatcaatattcctgatacggtcggcttcacgacaccagcagaatatggc
gcgattttcaaatacttaattgaccatgtcaaaacagaccgcgagattatctattctcct
cattgccatgatgatctaggtatggcagtcgctaatagcctcgctgctgtcaaaaatgga
gctggtcgtgtcgaagggaccatcaatggaatcggtgaacgggctggaaatgctgcgctt
gaagaagtggcagttgccctcaatatccgggaagactattaccaggttgacagtccgatt
gtgctcaatgaaaccattaacacctctgagttggtctctcgttactctggtattccaatt
cctaaaaacaaggcggttgttggtggcaatgccttctcgcacgagtctggaattcaccaa
gacggtgttcttaaaaatcctcttacctatgaaatcatcacgcctgagttggtgggtgtc
aagagcaatagccttcctcttgggaaattgtcagggcgccacgcctttgtcgaaaaactg
catgagttgggattggaattcacagaagaagacatcaagccattgtttgcgaaattcaaa
tctctggcagacaagaaacacgagatcacagacgctgatatccgagcccttgttgccggt
acagcagtggaaaatccagaaggcttccattttgatgatcttcgcctcacaacgaacgaa
gatgaaagcatcactgcaacagtcagcctgaaaaatgaagatggtgaaattcttgaatat
cttgccaaaggtcaaggttcagtggaagcaatctttaacgctattgatcaattcttccac
caagaagttcgtctgacctcttacagcattgatgcggtgacagatgggattgatgcccaa
gcgcgtgtactggttactgttgagaatgaagcgacagatactatctttaacgcttctggt
ttagactttgacgtattgaaggcctcagcaattgcctatatcaatgccaataccttggtg
caaaaagagaatgctggagagatcggccacattgtatcctatcgtgatctgcccgatgcc
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (25)   

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