KEGG   Streptomyces avermitilis: SAVERM_2748
Entry
SAVERM_2748       CDS       T00126                                 
Symbol
ligA
Name
(GenBank) putative DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
sma  Streptomyces avermitilis
Pathway
sma03030  DNA replication
sma03410  Base excision repair
sma03420  Nucleotide excision repair
sma03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:sma00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    SAVERM_2748 (ligA)
   03410 Base excision repair
    SAVERM_2748 (ligA)
   03420 Nucleotide excision repair
    SAVERM_2748 (ligA)
   03430 Mismatch repair
    SAVERM_2748 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:sma03032]
    SAVERM_2748 (ligA)
   03400 DNA repair and recombination proteins [BR:sma03400]
    SAVERM_2748 (ligA)
Enzymes [BR:sma01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     SAVERM_2748 (ligA)
DNA replication proteins [BR:sma03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     SAVERM_2748 (ligA)
DNA repair and recombination proteins [BR:sma03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     SAVERM_2748 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     SAVERM_2748 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     SAVERM_2748 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      SAVERM_2748 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD PTCB-BRCT HHH_5 HHH DUF6782
Other DBs
NCBI-ProteinID: BAC70459
NITE: SAV2748
UniProt: Q82JK7
Position
complement(3375523..3377715)
AA seq 730 aa
MAGEQHAQPTSVPAEAREKHAQLAEQIEEHRFRYYVKDAPVVSDAEFDTLLRSLEALEEE
YPELRTPDSPTQKVAGGYETEFTAVQHRERMLSLDNAFDDLGLAAWAERVAKDVGTSDYH
FLCELKVDGLAVNLTYEHGRLTRAATRGDGRTGEDITPNVRTIAEIPDRLKGDRIPDLVE
IRGEVYFPMEKFEELNARLVEAGDKPFANPRNAAAGSLRQKDPRVTATRPLHMVVHGIGA
RQGFDIDRLSQAYELLREWGLPTTRYARVVDDLDGVREFIAYYGENRHSVEHEIDGVVVK
LDEIPLQGRLGSTSRAPRWAIAWKYAPEEVNTKLINIRVGVGRTGRVTPYAQVEPVTVAG
SEVEFATLHNQDVVKAKGVLIGDTVVLRKAGDVIPEILGPVVDLRDGTERAFVMPAECPE
CGTPLAPAKEGDVDLRCPNARTCPAQLRERLFYLAGRKSLDIEQFGYVAAAALTKPLEPA
EPPLLDEGDLFDLTIERLLPIKAYVLDQDSGLPKRDPKTGEEKVATVFANQQGEPRKNAI
SMLDNIAAAKERPLARILTGLSIRHVGPVAAEALARAFRSIDRIDQATEEELKDTDGVGP
IVAAAVKQWFAEDWHREIIRKWKAAGVRMEDERSGEDEGPRPLEGLTVVVTGTLEHHTRD
GAKEALQSRGAKVTGSVSKKTSFVVVGDNPGSKYDKAMQLKVPVLNEAGFAVLLEQGPEA
AAEVALPTEE
NT seq 2193 nt   +upstreamnt  +downstreamnt
gtggccggcgaacagcacgcacagcccacatcggtacccgccgaggcacgggagaagcac
gcgcagctcgctgagcagatcgaggagcaccgcttccggtactacgtgaaggacgccccc
gtcgtcagcgacgcggagttcgacaccctcctgcgctccctcgaggcactggaggaggag
taccccgagctgcgcacgcccgactcaccgacccagaaggtcgcgggcgggtacgagacg
gagttcacggccgtccagcaccgtgagcgcatgctctccctggacaacgccttcgacgac
ctggggctggccgcctgggccgagcgcgtcgccaaggacgtcggcacctccgactaccac
ttcctgtgcgagctgaaggtcgacggcctcgccgtcaacctcacgtatgagcacggccgc
ctcacgcgcgcggcgacccgcggcgacggccgcacgggcgaggacatcacgcccaacgtc
cgtacgatcgcggagattccggaccgtctcaagggcgaccgcatcccggacctcgtggag
atccgcggcgaggtctacttcccgatggagaagttcgaggagctcaacgcacgtctggtg
gaggccggcgacaagcccttcgccaacccgcgcaacgcggcggcgggttcactgcgccag
aaggacccgcgggtcaccgcgacccgcccgctgcacatggtcgtccacggcatcggcgcc
cggcagggcttcgacatcgaccggctctcccaggcgtacgagctgctgcgcgagtggggc
ctgccgaccacccggtacgccagagtggtcgacgacctcgacggcgtacgggagttcatc
gcgtactacggggagaaccgccactccgtggagcacgagatcgacggcgtggtcgtgaag
ctcgacgagatcccgctccagggccgcctcggctccacctcccgcgcgccgcgctgggcg
atcgcctggaagtacgcgcccgaggaggtcaacaccaagctcatcaacatccgcgtgggc
gtggggcgtacgggccgggtcacgccgtacgcgcaggtggagccggtcacggtcgcgggc
tcggaggtcgagttcgccaccctgcacaaccaggacgtcgtcaaggccaagggcgtcctc
atcggggacacggtggtgctgcgcaaggccggtgacgtcatcccggagatcctcggcccg
gtcgtcgacctgcgcgacggcaccgagcgcgcgttcgtgatgcccgccgagtgccccgag
tgcggtacgccgctggcgccggccaaggagggcgacgtcgacctgcgctgcccgaacgcg
cgcacgtgtccggcccagctgcgggagcggctcttctatctcgcgggccgcaagtcgctc
gacatcgagcagttcggatatgtcgcggcggcggccctcaccaagccgctggagcccgcc
gagccgccgctgctcgacgagggcgacctcttcgacctcaccatcgaacggctgctgccc
atcaaggcgtacgtcctcgaccaggacagcggcctgcccaagcgggacccgaagacgggc
gaggagaaggtcgccacggtcttcgccaaccagcagggcgagccgcggaagaacgcgatc
tcgatgctggacaacatcgcggccgccaaggagcgcccgctcgcccggatcctgaccggt
ctgtcgatccgccacgtcgggccggtcgcggccgaggcgctggcgcgcgcgttccgctcg
atcgaccgcatcgaccaggccaccgaggaggagctgaaggacaccgacggtgtcggcccg
atcgtcgccgccgcggtcaagcagtggttcgccgaggactggcaccgggagatcatccga
aagtggaaggccgccggcgtccgcatggaggacgagcgctccggagaggacgaggggccg
cgcccgctcgaaggactcacggtcgtcgtcaccggaacgctcgaacaccacacgcgggac
ggcgcgaaggaggccctgcagagccgcggggcgaaagtcaccggttcggtttcgaagaag
acgtctttcgttgtcgtaggtgacaatcctggatcgaaatacgacaaggcgatgcagctg
aaggttcccgttctgaacgaggccggattcgccgttctgctcgagcaaggaccggaagcc
gctgcggaagtcgcacttccgaccgaggagtag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NITE (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (9)   
   Pfam (9)   
All databases (31)   

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