KEGG T01185: SmuNN2025

Streptococcus mutans NN2025: SmuNN2025_0117

Entry

SmuNN2025_0117 CDS T01185

Definition

dihydrolipoamide acetyltransferase

Orthology

K00627

pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]

Organism

smc Streptococcus mutans NN2025

Pathway

smc00010	Glycolysis / Gluconeogenesis
smc00020	Citrate cycle (TCA cycle)
smc00620	Pyruvate metabolism
smc01100	Metabolic pathways
smc01110	Biosynthesis of secondary metabolites
smc01120	Microbial metabolism in diverse environments
smc01200	Carbon metabolism

Module

smc_M00307

Pyruvate oxidation, pyruvate => acetyl-CoA

Class

Metabolism; Overview; Carbon metabolism [PATH:smc01200]
Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:smc00010]
Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:smc00020]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:smc00620]

SSDB

Motif

Pfam:

2-oxoacid_dh E3_binding Biotin_lipoyl Biotin_lipoyl_2 PLA2_B

Other DBs

NCBI-GI:

290579643

NCBI-GeneID:

8834282

UniProt:

C6STJ6

Position

138104..139471

AA seq 455 aa
MAVEIIMPKLGVDMQEGEIIEWKKQEGDEVKEGEILLEIMSDKTNMEIEAEDSGVLLKIV
KGNGQVVPVTEVIGYIGQAGEVLEIADVPASTVPKENSAAPAEKTKVMSSPTVAAAPQGK
VRATPAARKAARDLGVNLNQVSGTGAKGRVHKEDVESFKAAQPKATPLARKIAIDKGIDL
ASVSGTGFGGKIIKEDILNLFEAAQPVKDVSDPAKEAAALPEGVEVIKMSAMRKAVAKSM
VNSYLTAPTFTLNYDIDMTEMIALRKKLIDPIMEKTGFKVSFTDLIGLAVVKTLMKPEHR
YLNASLINDATEIELHQFVNLGIAVGLDEGLLVPVVHGADKMSLSDFVIASKDVIKKAQT
GKLKATEMSGSTFSITNLGMFGTKTFNPIINQPNSAILGVGATIQTPTVVDGEIKIRPIM
ALCLTIDHRLVDGMNGAKFMVDLKKLMENPFTLLI

NT seq 1368 nt +upstreamnt +downstreamnt
atggcagtcgaaattattatgcctaaacttggtgttgatatgcaggaaggcgaaatcatc
gagtggaaaaaacaagaaggtgatgaggtcaaagaaggggagatcctccttgagattatg
tctgacaagaccaatatggaaatcgaagctgaggattcaggtgtcctgcttaagattgtt
aaaggaaatggtcaagttgttcctgtaactgaggtcattggttatattggtcaagcaggt
gaagttcttgaaatagctgatgttcctgcaagtacagttcctaaagaaaatagtgcagca
cctgctgaaaaaacaaaagtaatgtcttctccgacagttgcagcagcccctcaaggaaag
gttcgagcaacaccagcagctcgtaaggcggctcgtgatctaggagttaacctgaatcag
gtttcagggacaggcgctaaaggccgtgttcacaaggaagatgttgaaagctttaaagca
gctcagcctaaagcaacaccattagctaggaaaattgctatagataaaggtattgatcta
gccagtgtctcaggaacaggttttggcggcaaaattatcaaggaagatattttaaatctg
tttgaggcagctcagcctgttaaagatgtgtcagatcctgctaaagaagcagctgcctta
ccagagggtgttgaagtcattaagatgtctgccatgcgtaaggcagtggctaaaagcatg
gtcaattcttacctgacagctccaacttttactctcaattatgacattgacatgactgag
atgattgcgttgcgtaaaaagttaattgatcctatcatggaaaaaacaggttttaaagtt
agcttcacagatttgattggtctggcggtcgtaaaaaccttaatgaaaccagaacatcgt
tacctcaatgcttcgctcattaatgacgcgactgagattgaacttcatcaatttgttaac
cttggtatcgccgttggacttgatgaaggactgttagtacctgttgttcatggtgcagat
aagatgagcttgtcagattttgttatagcttcaaaggatgtcattaagaaagctcagacc
ggtaaattaaaagccactgaaatgtctggttcaaccttttccattacaaacttggggatg
tttggcactaagactttcaaccccattatcaatcagccaaattcggctattttgggtgta
ggagcaactatccaaacgccaactgttgtggatggtgaaattaagattcgtccaatcatg
gcactgtgcttgaccatcgatcaccgcttggttgatggcatgaacggcgctaagttcatg
gttgatcttaaaaaactgatggaaaatccatttacattattgatttga

All links

Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (26)   

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