KEGG T00058: SMc02546

Sinorhizobium meliloti 1021: SMc02546

Entry

SMc02546 CDS T00058

Gene name

leuA2

Definition

alpha-isopropylmalate/homocitrate synthase family transferase

Orthology

K01649

2-isopropylmalate synthase [EC:2.3.3.13]

Organism

sme Sinorhizobium meliloti 1021

Pathway

sme00290	Valine, leucine and isoleucine biosynthesis
sme00620	Pyruvate metabolism
sme01100	Metabolic pathways
sme01110	Biosynthesis of secondary metabolites
sme01210	2-Oxocarboxylic acid metabolism
sme01230	Biosynthesis of amino acids

Module

sme_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Class

Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:sme00620]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH:sme00290]

SSDB

Motif

Pfam:

HMGL-like LeuA_dimer

Other DBs

NCBI-GI:

NCBI-GeneID:

RhizoBase:

UniProt:

Position

1213129..1214745

AA seq 538 aa
MTRERIYLFDTTLRDGQQTPGIDFSVEDKIAIASLLDQFGMDYVEGGYPGANPTDTEFFK
CRRTDKASFVAFGMTKRAGVSASNDPGLSALLSAKSDAICLVAKSWDYHVEVALGCTNEE
NLDNIRASVEAVVASGREAMVDCEHFFDGYKANSAYALACAKTAFEAGARWVVLCDTNGG
TQPPEIREIVSAVIAEGVPGANLGIHAHNDTGQAVANSLAAVEAGVRQIQGTLNGIGERC
GNANLVTLIATLALKETYSSRFETGIDAERLQELTKLAHAFDELLNRSPDPQAPYVGASA
FATKAGIHASALLKDPRTYEHVAPESVGNLRKVMVSDQGGKANFINALKRRGITVSKDDP
RLDKLISIVKEREATGYAYEGADASFALLASRILGTVPDFFRVESFRVMVERRFDANGKL
KTVSEAVVRVIVDGETMMSVAEGHGPVNALDLALRKDLGKYQSEIADLELADYKVRILNG
GTEAVTRVLIESTDRSGARWWTVGVSDNIIDASFQALMDSIVYKLLKNRDQVGSIAAE

NT seq 1617 nt +upstreamnt +downstreamnt
atgaccagggaacgcatctatctcttcgacacgacgcttcgggacgggcagcagacgccc
ggcatcgacttttccgtcgaggacaagatcgcgattgcgtcgctgcttgatcaattcggc
atggattatgtcgagggcggatatcccggcgccaatcccacggatacggagttcttcaag
tgccggcgcaccgacaaggcctccttcgtcgccttcggcatgaccaagcgcgccggcgtc
tccgcctccaacgacccgggcctgagcgcgctgctgagcgccaagagcgatgcgatctgt
cttgtcgccaagagctgggattatcatgtcgaggtggcgctcggctgtacgaacgaggaa
aatctcgacaatatccgcgcttccgtggaggcggtcgtggcttccggccgcgaggcgatg
gtcgattgcgagcatttcttcgacggctacaaggcgaactccgcctatgcgctcgcctgc
gcgaaaacggctttcgaggccggcgcgcgctgggtcgtgctttgcgacacgaatggcggc
acgcagcctcccgagatccgcgagatcgtctcggccgtgattgcggagggagtgcccggt
gcaaatctcggcatccatgcgcataatgatacggggcaggcggtggccaactcgctggct
gcggtggaagccggcgttcgtcagatccagggcacgctcaacggcatcggcgaacgctgc
ggcaatgccaatctcgtgacgctgattgcgacgcttgccctgaaggaaacctattcgagc
cgtttcgagacgggaatcgatgccgagaggctccaggaactgaccaagctcgcccatgcc
ttcgacgagttgctcaaccgctctccggatccccaggccccctatgtcggcgcttcggct
tttgccaccaaggccggcattcacgcctccgcgttgctcaaggatccgaggacctacgag
catgtcgcgccggaaagcgtcggcaacctgcgcaaggtcatggtctccgatcagggaggc
aaggccaacttcatcaatgctctcaagcggcgcggcatcacggtctccaaggacgatccg
cggctcgacaagctgatctcgatcgtcaaggaacgcgaggcgacgggctatgcctatgaa
ggtgcggatgcgagcttcgcgctgctcgcgagccgcattctcggcaccgtgcccgatttt
ttccgggtggagagcttccgggtgatggtcgagcgccgcttcgatgcgaacggcaagctg
aagacggtatcggaggccgtggtcagggtgatcgtcgacggcgaaacgatgatgtcggtc
gccgaggggcatggcccggtcaacgcgctcgacctcgcgcttcgcaaggatctcggcaag
taccagtccgagatcgccgatctggaacttgccgattacaaggtgcgcatcctcaacggc
ggcaccgaggccgtcacccgcgtcctgatcgaatcgacggaccgctcaggggcgcgctgg
tggacggtcggcgtatccgacaacatcatcgacgcctcatttcaggcattgatggacagt
atcgtctacaagctgctcaaaaaccgcgatcaggtcggatcgatcgcggccgagtag

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
   RHIZOBASE-SME (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (24)   

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