KEGG   Sinorhizobium meliloti RMO17: DU99_25595
Entry
DU99_25595        CDS       T03395                                 
Name
(GenBank) pyruvate dehydrogenase
  KO
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
Organism
smer  Sinorhizobium meliloti RMO17
Pathway
smer00280  Valine, leucine and isoleucine degradation
smer00640  Propanoate metabolism
smer00785  Lipoic acid metabolism
smer01100  Metabolic pathways
smer01110  Biosynthesis of secondary metabolites
smer01210  2-Oxocarboxylic acid metabolism
Module
smer_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:smer00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    DU99_25595
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    DU99_25595
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    DU99_25595
Enzymes [BR:smer01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     DU99_25595
SSDB
Motif
Pfam: Transketolase_C Transket_pyr E1_dh
Other DBs
NCBI-ProteinID: AIM02576
UniProt: A0AA91AAB4
Position
pSymB:29586..31664
AA seq 692 aa
MAQAALKKDRRNAPDESIDWKKVVQLLLLSRALDEMEEQRLVPEKKVLYQFSARGHDMAQ
ILLGLHLTGRHDAACGYYRSRPLLLALGVDPADALGSAMGRAGGYSDGRDIGVVFNYPNP
HGASALPMCGGVGTQYTPTAGWAQAITYFSEVLGKEEYQKDIAVVLGGDGSVASNGFWSA
LTIATTQGLPLLFYIEDNGFGISVPSSFQTPEGNIAGNLAGWKNLTVLDGDGSDPEEAAR
LTKGAVELVREGRMPVLLRLEVPRLEGHSFQDTQTYKSEELVRSEWAHDPLPRLRDYIVP
AMLSAEEWNEAARDAKAAAERARVEAESRPVADPETVTSHVFFEGRMQVMGGQHPAGYRP
PKTTETATGDGQRINMVTAIRRTLDHEMTVNQRVVLFGEDIGPKGGVHAVTLGLQEKFGT
ARVFDTSLSEEGIIGRAVGMALAGLVPVPEIQFRKYAEPAIEQLNDCGTIRWRTSNRFAA
PIVVRMAGGFFKCGDPWHSQTNEVAFVHQPGWKIAVPSNAEDAVGLLRTALRGNDPVIFF
EHRAMLDHPWARRPYPGDAFALPFGKAKFTREGRDITIVTWGAMVPRCEEAAEGISADVI
DLRTLMPWDRKAVIASVRRTRRCLIVHEDLATAGFGAEIAAAVADEAFIDLDAPISRLTM
PDIPSPHNPALLDWAVPSTERIRRKIIDLLEF
NT seq 2079 nt   +upstreamnt  +downstreamnt
atggctcaggccgcactcaaaaaggaccggcgcaacgcaccggacgagagcatcgactgg
aaaaaggtcgtgcaacttctgctcctgtcgcgcgcgctcgacgagatggaggagcagcgc
ctcgtccctgagaagaaggttctctaccagttctcggcacgcggccatgacatggcgcag
attctcctcgggcttcacctcactggcaggcacgacgcggcatgcggctattatcgctcg
cgcccgctgctgctggcgctcggcgtcgatccggcggacgcgctcggctcggcgatgggg
cgcgcgggcggatattccgacggccgggacatcggtgtcgtcttcaactatcccaacccg
cacggcgcctcggctttgccgatgtgcggaggggtcggcacccagtataccccgacggcc
ggctgggcgcaggcgatcacctatttcagcgaagttctcggaaaagaggaatatcaaaag
gatattgccgtcgtgctgggcggtgatggttcggtcgcctccaacggcttctggtccgct
ctgacgatcgcgacgacgcagggcctgccgctgctcttctatatcgaagacaacggcttc
ggcatctccgttccctcgagcttccagacgcccgaaggcaatattgccggcaacctcgcc
ggctggaaaaacttgaccgtgctcgacggcgacggctcggatccggaagaggccgcccgg
ctgacgaaaggcgccgtggaactggtgcgcgaagggcggatgccggtgctgctcaggctc
gaggtgccccgcctcgaaggacacagcttccaggatacccagacctacaagagcgaggag
ctcgtcaggagcgaatgggcacacgatccgttgccgcggctgagggactatatcgtccca
gccatgttgagcgccgaggaatggaacgaagctgcgagagacgcgaaggctgccgccgaa
cgggcgcgcgtcgaggccgaatcccggccggtcgccgatcccgaaaccgtcaccagccat
gtcttcttcgaaggccgaatgcaggtcatgggcgggcagcaccctgccggctatcgtccg
ccgaaaacgacggagacggcgacgggcgacggccagaggatcaacatggtgacggcgatc
cgccgcacgctcgatcacgagatgacggtgaaccagcgggtcgtcctcttcggggaagat
atcggcccgaagggcggcgttcatgccgtgaccctcgggctgcaggagaaattcggtacc
gcccgcgtcttcgacacgtcgctctcggaggagggcatcatcggccgggcggtcggcatg
gcgctcgcgggcctcgtaccggtgccggaaatccagttccgcaaatatgccgagcccgcg
atcgagcagctcaacgattgcggcacgatccgctggcggaccagcaaccgcttcgccgcg
ccgatcgtcgtgcggatggcggggggattcttcaaatgcggcgatccgtggcacagccag
acgaacgaggtcgccttcgtccaccagcccggctggaagatcgccgttccctccaatgcc
gaggacgccgtcgggctcctacgcaccgccttgcgcggcaacgatccggtgatcttcttc
gagcaccgggcgatgctcgaccatccctgggcgcggcggccctatcccggcgatgcattc
gccctgcccttcggcaaggcgaaattcacgcgcgaaggccgcgacatcaccatcgtcacc
tggggcgcaatggtgccgcgttgcgaagaggcggcagaggggatctcagccgacgtgatc
gatctgagaaccctgatgccatgggacaggaaagcggtcatcgcatccgtacgccgcacc
cgccggtgcctcatcgtccacgaggacctcgcaacagcgggtttcggcgcggagattgcc
gcagccgtcgccgacgaagccttcatcgatctcgacgcgccgatctcgcgcctcaccatg
ccggatattcccagcccccataatcccgccctgctcgactgggcggttccttcgacggaa
cgcatacgccggaagatcatcgaccttctggagttctga

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