ID CHED_BURPS Reviewed; 234 AA.
AC Q63PS1;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 28-MAR-2018, entry version 62.
DE RecName: Full=Probable chemoreceptor glutamine deamidase CheD {ECO:0000255|HAMAP-Rule:MF_01440};
DE EC=3.5.1.44 {ECO:0000255|HAMAP-Rule:MF_01440};
GN Name=cheD {ECO:0000255|HAMAP-Rule:MF_01440};
GN OrderedLocusNames=BPSL3302;
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243;
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M.,
RA Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L.,
RA Bentley S.D., Sebaihia M., Thomson N.R., Bason N., Beacham I.R.,
RA Brooks K., Brown K.A., Brown N.F., Challis G.L., Cherevach I.,
RA Chillingworth T., Cronin A., Crossett B., Davis P., DeShazer D.,
RA Feltwell T., Fraser A., Hance Z., Hauser H., Holroyd S., Jagels K.,
RA Keith K.E., Maddison M., Moule S., Price C., Quail M.A.,
RA Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M.,
RA Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis,
RT Burkholderia pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- FUNCTION: Probably deamidates glutamine residues to glutamate on
CC methyl-accepting chemotaxis receptors (MCPs), playing an important
CC role in chemotaxis. {ECO:0000255|HAMAP-Rule:MF_01440}.
CC -!- CATALYTIC ACTIVITY: Protein L-glutamine + H(2)O = protein L-
CC glutamate + NH(3). {ECO:0000255|HAMAP-Rule:MF_01440}.
CC -!- SIMILARITY: Belongs to the CheD family. {ECO:0000255|HAMAP-
CC Rule:MF_01440}.
DR EMBL; BX571965; CAH37315.1; -; Genomic_DNA.
DR RefSeq; WP_004524404.1; NZ_CP009538.1.
DR RefSeq; YP_109898.1; NC_006350.1.
DR ProteinModelPortal; Q63PS1; -.
DR SMR; Q63PS1; -.
DR STRING; 272560.BPSL3302; -.
DR EnsemblBacteria; CAH37315; CAH37315; BPSL3302.
DR GeneID; 3093671; -.
DR KEGG; bps:BPSL3302; -.
DR PATRIC; fig|272560.51.peg.1914; -.
DR eggNOG; ENOG4108Z4W; Bacteria.
DR eggNOG; COG1871; LUCA.
DR HOGENOM; HOG000273194; -.
DR KO; K03411; -.
DR OMA; VGMADLN; -.
DR BioCyc; BPSE272560:G1G3Q-3468-MONOMER; -.
DR Proteomes; UP000000605; Chromosome 1.
DR GO; GO:0050568; F:protein-glutamine glutaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR CDD; cd16352; CheD; 1.
DR Gene3D; 3.30.1330.200; -; 1.
DR HAMAP; MF_01440; CheD; 1.
DR InterPro; IPR038592; CheD-like_sf.
DR InterPro; IPR005659; Chemorcpt_Glu_NH3ase_CheD.
DR InterPro; IPR011324; Cytotoxic_necrot_fac-like_cat.
DR PANTHER; PTHR35147; PTHR35147; 1.
DR Pfam; PF03975; CheD; 1.
DR SUPFAM; SSF64438; SSF64438; 1.
PE 3: Inferred from homology;
KW Chemotaxis; Complete proteome; Hydrolase; Reference proteome.
FT CHAIN 1 234 Probable chemoreceptor glutamine
FT deamidase CheD.
FT /FTId=PRO_0000251014.
SQ SEQUENCE 234 AA; 25712 MW; 8BB52AC949315C22 CRC64;
MSGLPIATNL YFDAHFHRHG VKLLPNEFYT TREDMVLVTV LGSCVAACLH DPIGRIGGMN
HFMLPDDGAD PSAAASESMR YGAYAMEVLI NELIKAGGRR ERFEAKVFGG AAVLAGMTTI
NIGDRNADFV RRYLALERIR ITAEDLQGVH PRKVAFMPHT GQAMVKKLRV QAPDVAAREA
ALAREAVDPH GERAPRVRPR VELFGTPAPK AQAKPRIELF GMRAMQPATR KQEA
//
