ID EX7L_SALAR Reviewed; 454 AA.
AC A9MHM3;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 01-MAY-2013, entry version 37.
DE RecName: Full=Exodeoxyribonuclease 7 large subunit;
DE EC=3.1.11.6;
DE AltName: Full=Exodeoxyribonuclease VII large subunit;
DE Short=Exonuclease VII large subunit;
GN Name=xseA; OrderedLocusNames=SARI_00364;
OS Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=41514;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-731 / CDC346-86 / RSK2980;
RG The Salmonella enterica serovar Arizonae Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V.,
RA Nash W., Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Bidirectionally degrades single-stranded DNA into large
CC acid-insoluble oligonucleotides, which are then degraded further
CC into small acid-soluble oligonucleotides (By similarity).
CC -!- CATALYTIC ACTIVITY: Exonucleolytic cleavage in either 5'- to 3'-
CC or 3'- to 5'-direction to yield nucleoside 5'-phosphates.
CC -!- SUBUNIT: Heterooligomer composed of large and small subunits (By
CC similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the XseA family.
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DR EMBL; CP000880; ABX20301.1; -; Genomic_DNA.
DR RefSeq; YP_001569443.1; NC_010067.1.
DR STRING; 41514.SARI_00364; -.
DR EnsemblBacteria; ABX20301; ABX20301; SARI_00364.
DR GeneID; 5764383; -.
DR KEGG; ses:SARI_00364; -.
DR PATRIC; 18469881; VBISalEnt13497_0338.
DR eggNOG; COG1570; -.
DR HOGENOM; HOG000229265; -.
DR KO; K03601; -.
DR OMA; ENAQVRC; -.
DR ProtClustDB; PRK00286; -.
DR BioCyc; SENT882884:GJ8H-364-MONOMER; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:HAMAP.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:HAMAP.
DR GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC.
DR HAMAP; MF_00378; Exonuc_7_L; 1; -.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
DR TIGRFAMs; TIGR00237; xseA; 1.
PE 3: Inferred from homology;
KW Complete proteome; Cytoplasm; Exonuclease; Hydrolase; Nuclease.
FT CHAIN 1 454 Exodeoxyribonuclease 7 large subunit.
FT /FTId=PRO_1000079989.
SQ SEQUENCE 454 AA; 51566 MW; 639A4BEAFE48FA12 CRC64;
MLSSQTSSIF TVSRLNQTVR LLLEQEMGQV WISGEISNFT QPASGHWYFT LKDDTAQVRC
AMFRNSNRRV TFRPQHGQQV LVRANITLYE PRGDYQIIVE SMQPAGEGLL QQKYEQLKAK
LQAEGLFDQQ YKHPLPSPAY CVGVITSKTG AALHDILHVL KRRDPSLPVI IYPAAVQGED
APGQIVRAIT LANARKECDV LIVGRGGGSL EDLWSFNDER VARAIFASTI PVVSAVGHET
DVTIADFVAD LRAPTPSAAA EVVSRNQQEL LRQMQTACQR LEMAMDYYLA NRQRRFSQLY
HRLQQQHPQL RLARQQTTLE RLRQRMHLAL ENQLKQANQR QQRASQRLRQ QNPQPRIHRA
QSRIQQLEYR LAENFRARLS EQRERFGNTV THLEAVSPLA TLARGYSVST ATDGNVLKKV
KQLKVGDMMT TRLKDGWVTS EVTAIKPVKK IRLG
//
