ID GLPK_RHOP5 Reviewed; 500 AA.
AC Q07K31;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2006, sequence version 1.
DT 01-MAY-2013, entry version 49.
DE RecName: Full=Glycerol kinase;
DE EC=2.7.1.30;
DE AltName: Full=ATP:glycerol 3-phosphotransferase;
DE AltName: Full=Glycerokinase;
DE Short=GK;
GN Name=glpK; OrderedLocusNames=RPE_3774;
OS Rhodopseudomonas palustris (strain BisA53).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC Bradyrhizobiaceae; Rhodopseudomonas.
OX NCBI_TaxID=316055;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BisA53;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N., Kim E.,
RA Harwood C.S., Oda Y., Richardson P.;
RT "Complete sequence of Rhodopseudomonas palustris BisA53.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Key enzyme in the regulation of glycerol uptake and
CC metabolism (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-
CC phosphate.
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol
CC kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
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DR EMBL; CP000463; ABJ07703.1; -; Genomic_DNA.
DR RefSeq; YP_782683.1; NC_008435.1.
DR ProteinModelPortal; Q07K31; -.
DR SMR; Q07K31; 3-493.
DR STRING; 316055.RPE_3774; -.
DR EnsemblBacteria; ABJ07703; ABJ07703; RPE_3774.
DR GeneID; 4361466; -.
DR KEGG; rpe:RPE_3774; -.
DR PATRIC; 23262172; VBIRhoPal93214_3817.
DR eggNOG; COG0554; -.
DR HOGENOM; HOG000222134; -.
DR KO; K00864; -.
DR OMA; GQKEFTQ; -.
DR ProtClustDB; CLSK818559; -.
DR BioCyc; RPAL316055:GHR9-3829-MONOMER; -.
DR UniPathway; UPA00618; UER00672.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP.
DR HAMAP; MF_00186; Glycerol_kin; 1; -.
DR InterPro; IPR018485; Carb_kinase_FGGY_C.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018484; Carb_kinase_FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR PANTHER; PTHR10196:SF9; PTHR10196:SF9; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR TIGRFAMs; TIGR01311; glycerol_kin; 1.
DR PROSITE; PS00933; FGGY_KINASES_1; FALSE_NEG.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Glycerol metabolism; Kinase;
KW Nucleotide-binding; Transferase.
FT CHAIN 1 500 Glycerol kinase.
FT /FTId=PRO_1000020766.
FT NP_BIND 411 415 ATP (By similarity).
FT BINDING 11 11 Substrate (By similarity).
FT BINDING 15 15 ATP (By similarity).
FT BINDING 81 81 Substrate (By similarity).
FT BINDING 133 133 Substrate (By similarity).
FT BINDING 242 242 Substrate (By similarity).
FT BINDING 264 264 ATP (By similarity).
FT BINDING 307 307 ATP; via carbonyl oxygen (By similarity).
SQ SEQUENCE 500 AA; 54025 MW; 3EE4C2F1E5D927C5 CRC64;
MSFVLAIDQG TTSSRAIVFR DDISIAAVAQ QEFSQHFPAS GWVEHEPEDI WSSTLATSRA
AIEQAGLKAS DIAAIGITNQ RETVVLWDRV TGQAIHRAIV WQDRRTSEIC ARLKSEGHEP
LITQKTGLII DPYFSGTKIG WLLDQVPGAR ARAERGELLF GTVDCYLLWR LTGGKIHATD
ATNASRTLLF NIHTGQWDAE LLALLNVPRS LLPEVKDSSA DFGTSDQNLF GGSIAIRGIA
GDQQAATIGQ ACFAPGMMKS TYGTGCFALL NTGSTPVKSN NKLLTTIAYQ LNGQRTYALE
GSIFVAGSAV QWLRDGLGII SHASETGPLA DKSDSTQSVY LVPAFVGLGA PYWNPRLRGA
LFGLTRNTGP AELAHAALES VCYQTFDLWA AMRADWPDAD EASIVLRVDG GMTASDWTMQ
RLADLLDAPV DRPMIQETTA LGAAYLAGLS AGIFPEPQQF ADNWRLQHRF KPSMSAATRA
RKLKGWAAAV RGLLATDEGE
//
