ID K6PF_CHLAD Reviewed; 356 AA.
AC B8GAA4;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 29-MAY-2013, entry version 33.
DE RecName: Full=6-phosphofructokinase;
DE Short=Phosphofructokinase;
DE EC=2.7.1.11;
DE AltName: Full=Phosphohexokinase;
GN Name=pfkA; OrderedLocusNames=Cagg_3643;
OS Chloroflexus aggregans (strain MD-66 / DSM 9485).
OC Bacteria; Chloroflexi; Chloroflexales; Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=326427;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-66 / DSM 9485;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Foster B., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.;
RT "Complete sequence of Chloroflexus aggregans DSM 9485.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC fructose 1,6-bisphosphate.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 3/4.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the phosphofructokinase family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CP001337; ACL26479.1; -; Genomic_DNA.
DR RefSeq; YP_002464915.1; NC_011831.1.
DR ProteinModelPortal; B8GAA4; -.
DR STRING; 326427.Cagg_3643; -.
DR EnsemblBacteria; ACL26479; ACL26479; Cagg_3643.
DR GeneID; 7269787; -.
DR KEGG; cag:Cagg_3643; -.
DR PATRIC; 21409998; VBIChlAgg85409_3759.
DR eggNOG; COG0205; -.
DR HOGENOM; HOG000248869; -.
DR KO; K00850; -.
DR OMA; SAQANIC; -.
DR ProtClustDB; CLSK983903; -.
DR BioCyc; CAGG326427:GHS8-3694-MONOMER; -.
DR UniPathway; UPA00109; UER00182.
DR GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:HAMAP.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR HAMAP; MF_00339; Phosphofructokinase; 1; -.
DR InterPro; IPR012003; ATP_PFK_prok.
DR InterPro; IPR012829; PFK.
DR InterPro; IPR022953; Phosphofructokinase.
DR InterPro; IPR015912; Phosphofructokinase_CS.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR Pfam; PF00365; PFK; 1.
DR PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Ppfruckinase; 1.
DR TIGRFAMs; TIGR02483; PFK_mixed; 1.
DR PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW Magnesium; Metal-binding; Nucleotide-binding; Transferase.
FT CHAIN 1 356 6-phosphofructokinase.
FT /FTId=PRO_1000192367.
FT NP_BIND 25 29 ATP (By similarity).
FT NP_BIND 167 171 ATP (By similarity).
FT NP_BIND 184 200 ATP (By similarity).
FT ACT_SITE 140 140 Proton acceptor (By similarity).
FT METAL 198 198 Magnesium; via carbonyl oxygen (By
FT similarity).
FT METAL 200 200 Magnesium (By similarity).
FT BINDING 175 175 Substrate (By similarity).
FT BINDING 272 272 Substrate (By similarity).
FT BINDING 278 278 Substrate (By similarity).
FT BINDING 281 281 Substrate (By similarity).
SQ SEQUENCE 356 AA; 37734 MW; 66436D7A5E6F4579 CRC64;
MASKKQRIGV LTSGGDAPGL NAVIRAVVKS ASSLGWEVIG IHDGFEGLLG TKSYRVLTNA
DVQGLLPRGG TILRTTNKGH FGPRRSDELS EADPYVRAVK AIEEMGLRAL ITIGGEGTQR
IALELHKLGA PVIGVPKTID NDLAGTDRTF GFDTALQVAT DAIDRLHTTA ASHNRVMVLE
VMGRHTGWIA LHAGLAGGAD VILIPEIPFT IERVAEKVHA RDAQGSAFSI IVVAEGARPR
GGSEMYIAEG RLGGIGHWVG EQLERLTGKD VRVVVLGHLQ RGGSPSPYDR LLSTRYGAAA
VQAAARGIYG EMVALRGQDI VTVPLAEACG YLNRVRPHSD LVLCARSLGI VFGDEL
//
