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Database: UniProt/SWISS-PROT
Entry: K6PF_CHLAD
LinkDB: K6PF_CHLAD
Original site: K6PF_CHLAD 
ID   K6PF_CHLAD              Reviewed;         356 AA.
AC   B8GAA4;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   19-FEB-2014, entry version 36.
DE   RecName: Full=6-phosphofructokinase;
DE            Short=Phosphofructokinase;
DE            EC=2.7.1.11;
DE   AltName: Full=Phosphohexokinase;
GN   Name=pfkA; OrderedLocusNames=Cagg_3643;
OS   Chloroflexus aggregans (strain MD-66 / DSM 9485).
OC   Bacteria; Chloroflexi; Chloroflexales; Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=326427;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MD-66 / DSM 9485;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Foster B., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.;
RT   "Complete sequence of Chloroflexus aggregans DSM 9485.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC       fructose 1,6-bisphosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 3/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphofructokinase family.
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DR   EMBL; CP001337; ACL26479.1; -; Genomic_DNA.
DR   RefSeq; YP_002464915.1; NC_011831.1.
DR   ProteinModelPortal; B8GAA4; -.
DR   STRING; 326427.Cagg_3643; -.
DR   EnsemblBacteria; ACL26479; ACL26479; Cagg_3643.
DR   GeneID; 7269787; -.
DR   KEGG; cag:Cagg_3643; -.
DR   PATRIC; 21409998; VBIChlAgg85409_3759.
DR   eggNOG; COG0205; -.
DR   HOGENOM; HOG000248869; -.
DR   KO; K00850; -.
DR   OMA; WVGLMED; -.
DR   OrthoDB; EOG644ZRM; -.
DR   ProtClustDB; CLSK983903; -.
DR   BioCyc; CAGG326427:GHS8-3694-MONOMER; -.
DR   UniPathway; UPA00109; UER00182.
DR   GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IEA:GOC.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_00339; Phosphofructokinase; 1.
DR   InterPro; IPR012003; ATP_PFK_prok.
DR   InterPro; IPR012829; PFK.
DR   InterPro; IPR022953; Phosphofructokinase.
DR   InterPro; IPR015912; Phosphofructokinase_CS.
DR   InterPro; IPR000023; Phosphofructokinase_dom.
DR   Pfam; PF00365; PFK; 1.
DR   PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR   PRINTS; PR00476; PHFRCTKINASE.
DR   SUPFAM; SSF53784; SSF53784; 1.
DR   TIGRFAMs; TIGR02483; PFK_mixed; 1.
DR   PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW   Magnesium; Metal-binding; Nucleotide-binding; Transferase.
FT   CHAIN         1    356       6-phosphofructokinase.
FT                                /FTId=PRO_1000192367.
FT   NP_BIND      25     29       ATP (By similarity).
FT   NP_BIND     167    171       ATP (By similarity).
FT   NP_BIND     184    200       ATP (By similarity).
FT   ACT_SITE    140    140       Proton acceptor (By similarity).
FT   METAL       198    198       Magnesium; via carbonyl oxygen (By
FT                                similarity).
FT   METAL       200    200       Magnesium (By similarity).
FT   BINDING     175    175       Substrate (By similarity).
FT   BINDING     272    272       Substrate (By similarity).
FT   BINDING     278    278       Substrate (By similarity).
FT   BINDING     281    281       Substrate (By similarity).
SQ   SEQUENCE   356 AA;  37734 MW;  66436D7A5E6F4579 CRC64;
     MASKKQRIGV LTSGGDAPGL NAVIRAVVKS ASSLGWEVIG IHDGFEGLLG TKSYRVLTNA
     DVQGLLPRGG TILRTTNKGH FGPRRSDELS EADPYVRAVK AIEEMGLRAL ITIGGEGTQR
     IALELHKLGA PVIGVPKTID NDLAGTDRTF GFDTALQVAT DAIDRLHTTA ASHNRVMVLE
     VMGRHTGWIA LHAGLAGGAD VILIPEIPFT IERVAEKVHA RDAQGSAFSI IVVAEGARPR
     GGSEMYIAEG RLGGIGHWVG EQLERLTGKD VRVVVLGHLQ RGGSPSPYDR LLSTRYGAAA
     VQAAARGIYG EMVALRGQDI VTVPLAEACG YLNRVRPHSD LVLCARSLGI VFGDEL
//
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