ID MASZ_OCHA4 Reviewed; 728 AA.
AC A6WYD2;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 01-MAY-2013, entry version 42.
DE RecName: Full=Malate synthase G;
DE EC=2.3.3.9;
GN Name=glcB; OrderedLocusNames=Oant_1269;
OS Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC Brucellaceae; Ochrobactrum.
OX NCBI_TaxID=439375;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49188 / DSM 6882 / NCTC 12168;
RX PubMed=21685287; DOI=10.1128/JB.05335-11;
RA Chain P.S., Lang D.M., Comerci D.J., Malfatti S.A., Vergez L.M.,
RA Shin M., Ugalde R.A., Garcia E., Tolmasky M.E.;
RT "Genome of Ochrobactrum anthropi ATCC 49188 T, a versatile
RT opportunistic pathogen and symbiont of several eukaryotic hosts.";
RL J. Bacteriol. 193:4274-4275(2011).
CC -!- CATALYTIC ACTIVITY: Acetyl-CoA + H(2)O + glyoxylate = (S)-malate +
CC CoA.
CC -!- PATHWAY: Carbohydrate metabolism; glyoxylate cycle; (S)-malate
CC from isocitrate: step 2/2.
CC -!- SUBUNIT: Monomer (By similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the malate synthase family. GlcB subfamily.
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DR EMBL; CP000758; ABS13986.1; -; Genomic_DNA.
DR RefSeq; YP_001369815.1; NC_009667.1.
DR ProteinModelPortal; A6WYD2; -.
DR SMR; A6WYD2; 10-728.
DR STRING; 439375.Oant_1269; -.
DR EnsemblBacteria; ABS13986; ABS13986; Oant_1269.
DR GeneID; 5378625; -.
DR KEGG; oan:Oant_1269; -.
DR PATRIC; 20467633; VBIOchAnt73124_1330.
DR eggNOG; COG2225; -.
DR HOGENOM; HOG000220740; -.
DR KO; K01638; -.
DR OMA; VVKPKMH; -.
DR ProtClustDB; PRK02999; -.
DR BioCyc; OANT439375:GJIT-1286-MONOMER; -.
DR UniPathway; UPA00703; UER00720.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004474; F:malate synthase activity; IEA:HAMAP.
DR GO; GO:0006097; P:glyoxylate cycle; IEA:HAMAP.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR Gene3D; 2.170.170.11; -; 2.
DR HAMAP; MF_00641; Malate_synth_G; 1; -.
DR InterPro; IPR011076; Malate_synth-like.
DR InterPro; IPR023310; Malate_synth_G_beta_sub_dom.
DR InterPro; IPR001465; Malate_synthase.
DR InterPro; IPR006253; Malate_synthG.
DR PANTHER; PTHR21631:SF1; PTHR21631:SF1; 1.
DR Pfam; PF01274; Malate_synthase; 1.
DR SUPFAM; SSF51645; Malat_synth_like; 1.
DR TIGRFAMs; TIGR01345; malate_syn_G; 1.
PE 3: Inferred from homology;
KW Complete proteome; Cytoplasm; Glyoxylate bypass; Transferase;
KW Tricarboxylic acid cycle.
FT CHAIN 1 728 Malate synthase G.
FT /FTId=PRO_1000056916.
FT ACT_SITE 345 345 Proton acceptor (By similarity).
FT ACT_SITE 636 636 Proton donor (By similarity).
SQ SEQUENCE 728 AA; 79664 MW; 89C758B66592CB10 CRC64;
MVSQKAGNYV EIEGLRVAPE LVEFLAKEAA PGTGVEPEKF WKGFAAIIRD LAPKNRALLA
KRDDLQAKID AWYKQNRDKG YSQADYQQFL KNIGYLLPEG GEFSVSTTNV DPEITHIAGP
QLVVPVMNAR YALNAANARW GSLYDALYGT DAISDADGGE KGKGYNPKRG EKVIAWAKNF
LDESAPLATG NWANVAGLAV KDGKLEIKLT DGSATALKDA NQFKGYNGDA AAPTNVLLAK
NNMHVDIVVN ADHPIGKTDP AHIADVVLES AVSTIQDCED SIAAVDAEDK VAVYRNWLGL
MNGKLEDTFE KNGKQMTRRL NGDRSYKAAD GSTLSLKGRS LMLVRNVGHL MTNPAIIDAD
GHEVPEGIMD AAFTSLIALH DIGPNGRHMN SREGSVYIVK PKMHGPEEVA FANEIFTRTE
EMLGMKPNTL KIGIMDEERR TTVNLKEAIR AAKERVVFIN TGFLDRTGDE IHTSMEAGPM
IRKGDMKQAA WIGAYEQWNV DIGLECGLSG HAQIGKGMWA MPDLMAAMLE QKIAHPKAGA
NTAWVPSPTA ATLHATHYHQ VDVAAVQAKL KSRPRAKLDD ILSVPVATRP NWTPEDIQHE
IDNNAQGILG YVVRWVDQGV GCSKVPDINN VGLMEDRATL RISAQHIANW LYHGVVSEAQ
VMETMKRMAA VVDKQNEGDA LYRPMAADFD KSIAFQAACD LVFKGREQPN GYTEPVLHRR
RLELKAQG
//
