ID NOB1_PONAB Reviewed; 411 AA.
AC Q5RBB3; Q5RED4;
DT 02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 06-MAR-2013, entry version 47.
DE RecName: Full=RNA-binding protein NOB1;
GN Name=NOB1;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex, and Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in mRNA degradation (By similarity).
CC -!- SUBUNIT: May interact with UPF2 (Probable).
CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC -!- SIMILARITY: Belongs to the NOB1 family.
CC -!- SIMILARITY: Contains 1 PINc domain.
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DR EMBL; CR857596; CAH89873.1; -; Transcribed_RNA.
DR EMBL; CR858738; CAH90947.1; -; mRNA.
DR RefSeq; NP_001127354.1; NM_001133882.1.
DR UniGene; Pab.19169; -.
DR ProteinModelPortal; Q5RBB3; -.
DR SMR; Q5RBB3; 259-324.
DR Ensembl; ENSPPYT00000008825; ENSPPYP00000008479; ENSPPYG00000007509.
DR GeneID; 100174418; -.
DR KEGG; pon:100174418; -.
DR CTD; 28987; -.
DR GeneTree; ENSGT00390000015857; -.
DR HOVERGEN; HBG057385; -.
DR InParanoid; Q5RBB3; -.
DR KO; K11883; -.
DR OMA; KEPLPEY; -.
DR OrthoDB; EOG4S4PGJ; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR017117; D-site_20S_pre-rRNA_nuclease.
DR InterPro; IPR014881; NOB1_Zn-bd.
DR InterPro; IPR006596; PINc_nuc-bd.
DR Pfam; PF08772; NOB1_Zn_bind; 1.
DR PIRSF; PIRSF037125; D-site_20S_pre-rRNA_nuclease; 1.
DR SMART; SM00670; PINc; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Metal-binding; Nucleus; Phosphoprotein;
KW Reference proteome; Zinc.
FT INIT_MET 1 1 Removed (By similarity).
FT CHAIN 2 411 RNA-binding protein NOB1.
FT /FTId=PRO_0000233268.
FT DOMAIN 5 108 PINc.
FT COMPBIAS 186 190 Poly-Glu.
FT METAL 269 269 Zinc (By similarity).
FT METAL 272 272 Zinc (By similarity).
FT METAL 284 284 Zinc (By similarity).
FT METAL 287 287 Zinc (By similarity).
FT MOD_RES 184 184 Phosphoserine (By similarity).
FT MOD_RES 200 200 Phosphoserine (By similarity).
FT MOD_RES 351 351 Phosphoserine (By similarity).
FT CONFLICT 20 20 L -> LQ (in Ref. 1; CAH89873).
SQ SEQUENCE 411 AA; 46500 MW; 73601D5EBB91FEA9 CRC64;
MAPVEHVVAD AGAFLRDAAL QDIGKNIYTI REVVTEIRDK ATRRRLAVLP YELRFKEPLP
EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKQEPQKV KVSSSIQHPE
TPLHISGFHL PSKPKPPQET EKGHPACEPE NLEFSSFMFW RNPLPNIDHE LQELLIDRGE
DIPSDEEEEE NGFEDRRDDS DDDGGGWITP SNIKQIQQEL EQCDVPEDVR VGCVTTDFAM
QNVLLQMGLH VLAVNGMLIR EARSYILRCH GCFKTTSDMS RVFCSHCGNK TLKKVSVTVS
DDGTLHMHFS RNPKVLNPRG LRYSLPTPKG GKYAINPHLT EDQRFPQLRL SRKARQKTNV
FAPDYVAGVS PFVENDISSR SATLQVRDSS LGAGRRRLNP NASRRKFVKK R
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