ID PCKA_YERPS Reviewed; 539 AA.
AC Q664K7;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 01-MAY-2013, entry version 59.
DE RecName: Full=Phosphoenolpyruvate carboxykinase [ATP];
DE Short=PEP carboxykinase;
DE Short=PEPCK;
DE EC=4.1.1.49;
DE AltName: Full=Phosphoenolpyruvate carboxylase;
GN Name=pckA; OrderedLocusNames=YPTB3762;
OS Yersinia pseudotuberculosis serotype I (strain IP32953).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Yersinia.
OX NCBI_TaxID=273123;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP32953;
RX PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA Derbise A., Hauser L.J., Garcia E.;
RT "Insights into the evolution of Yersinia pestis through whole-genome
RT comparison with Yersinia pseudotuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC -!- CATALYTIC ACTIVITY: ATP + oxaloacetate = ADP + phosphoenolpyruvate
CC + CO(2).
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [ATP]
CC family.
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DR EMBL; BX936398; CAH23000.1; -; Genomic_DNA.
DR RefSeq; YP_072243.1; NC_006155.1.
DR ProteinModelPortal; Q664K7; -.
DR SMR; Q664K7; 5-539.
DR STRING; 273123.YPTB3762; -.
DR EnsemblBacteria; CAH23000; CAH23000; YPTB3762.
DR GeneID; 2956216; -.
DR KEGG; yps:YPTB3762; -.
DR PATRIC; 18646947; VBIYerPse22266_4506.
DR eggNOG; COG1866; -.
DR HOGENOM; HOG000271471; -.
DR KO; K01610; -.
DR OMA; TRCAYPI; -.
DR ProtClustDB; PRK09344; -.
DR UniPathway; UPA00138; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:HAMAP.
DR GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR Gene3D; 3.40.449.10; -; 1.
DR Gene3D; 3.90.228.20; -; 2.
DR HAMAP; MF_00453; PEPCK_ATP; 1; -.
DR InterPro; IPR001272; PEP_carboxykinase_ATP.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR InterPro; IPR015994; PEPCK_ATP_CS.
DR Pfam; PF01293; PEPCK_ATP; 1.
DR PIRSF; PIRSF006294; PEP_crbxkin; 1.
DR SUPFAM; SSF68923; PEP_carboxykinase_N; 1.
DR TIGRFAMs; TIGR00224; pckA; 1.
DR PROSITE; PS00532; PEPCK_ATP; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Cytoplasm; Decarboxylase;
KW Gluconeogenesis; Lyase; Nucleotide-binding.
FT CHAIN 1 539 Phosphoenolpyruvate carboxykinase [ATP].
FT /FTId=PRO_0000203860.
FT NP_BIND 247 254 ATP (By similarity).
SQ SEQUENCE 539 AA; 59321 MW; 5A379FB1417974DB CRC64;
MSVKGITPQE LAAYGIHNVS EIVYNPSYDL LFEEETKPTL EGYERGTLTT TGAIAVDTGI
FTGRSPKDKY IVRDAITQDT VWWADQGKGK NDNKPLSQEI WSHLKGLVTE QLSGKRLFVV
DTFCGANADT RLQVRFITEV AWQAHFVKNM FIRPSDEELA RFEPDFIVMN GAKCTNPQWK
EQGLNSENFV AFNLTERMQL IGGTWYGGEM KKGMFSMMNY LLPLKGIASM HCSANVGEKG
DVAIFFGLSG TGKTTLSTDP KRKLIGDDEH GWDDDGVFNF EGGCYAKTIK LSEEAEPDIY
HAIKRDALLE NVVVLADGTV DFNDGSKTEN TRVSYPIYHI DNIVKPVSKA GHATKVIFLT
ADAFGVLPPV SRLTANQTQY HFLSGFTAKL AGTERGVTEP TPTFSACFGA AFLSLHPTQY
AEVLVKRMQA VGAQAYLVNT GWNGTGKRIS IKDTRAIIDA ILNGEIDKAE TFTLPIFDLA
VPMALPGVNP DILDPRDTYA DKAQWQEKAE DLAKRFATNF DKYTDTPAGA ALVSAGPKI
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