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Database: UniProt/SWISS-PROT
Entry: TRUB_CORGB
LinkDB: TRUB_CORGB
Original site: TRUB_CORGB 
ID   TRUB_CORGB              Reviewed;         297 AA.
AC   A4QEY6;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   14-MAY-2014, entry version 48.
DE   RecName: Full=tRNA pseudouridine synthase B;
DE            EC=5.4.99.25;
DE   AltName: Full=tRNA pseudouridine(55) synthase;
DE            Short=Psi55 synthase;
DE   AltName: Full=tRNA pseudouridylate synthase;
DE   AltName: Full=tRNA-uridine isomerase;
GN   Name=truB; OrderedLocusNames=cgR_1808;
OS   Corynebacterium glutamicum (strain R).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=340322;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R;
RX   PubMed=17379713; DOI=10.1099/mic.0.2006/003657-0;
RA   Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N.,
RA   Suda M., Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.;
RT   "Comparative analysis of the Corynebacterium glutamicum group and
RT   complete genome sequence of strain R.";
RL   Microbiology 153:1042-1058(2007).
CC   -!- FUNCTION: Responsible for synthesis of pseudouridine from uracil-
CC       55 in the psi GC loop of transfer RNAs (By similarity).
CC   -!- CATALYTIC ACTIVITY: tRNA uridine(55) = tRNA pseudouridine(55).
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase TruB family.
CC       Type 1 subfamily.
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DR   EMBL; AP009044; BAF54802.1; -; Genomic_DNA.
DR   RefSeq; YP_001138704.1; NC_009342.1.
DR   ProteinModelPortal; A4QEY6; -.
DR   STRING; 340322.cgR_1808; -.
DR   EnsemblBacteria; BAF54802; BAF54802; cgR_1808.
DR   GeneID; 4994252; -.
DR   KEGG; cgt:cgR_1808; -.
DR   PATRIC; 21508228; VBICorGlu58097_1861.
DR   eggNOG; COG0130; -.
DR   HOGENOM; HOG000231225; -.
DR   KO; K03177; -.
DR   OMA; IQPIDAF; -.
DR   OrthoDB; EOG6358D3; -.
DR   BioCyc; CGLU340322:GJBE-1888-MONOMER; -.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0031119; P:tRNA pseudouridine synthesis; IEA:UniProtKB-HAMAP.
DR   HAMAP; MF_01080; TruB_bact; 1.
DR   InterPro; IPR002501; PsdUridine_synth.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR   InterPro; IPR015947; PUA-like_domain.
DR   InterPro; IPR015225; tRNA_psdUridine_synth_fam2_C.
DR   InterPro; IPR014780; tRNA_psdUridine_synth_TruB.
DR   PANTHER; PTHR13767; PTHR13767; 1.
DR   Pfam; PF09142; TruB_C; 1.
DR   Pfam; PF01509; TruB_N; 1.
DR   SUPFAM; SSF55120; SSF55120; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00431; TruB; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase; tRNA processing.
FT   CHAIN         1    297       tRNA pseudouridine synthase B.
FT                                /FTId=PRO_1000084577.
FT   ACT_SITE     44     44       Nucleophile (By similarity).
SQ   SEQUENCE   297 AA;  31846 MW;  7909C21F4FAF6B12 CRC64;
     MNAPAPKPGL VIVDKPAGMT SHDVVSKLRR AFSTRKVGHA GTLDPMATGV LVVGIERGTR
     FLAHMVASTK AYDATIRLGA ATSTDDAEGE VISTTDASGL DHRAILAEIA NLTGDIMQKP
     TKVSAIKIDG KRAHERVRDG EEVDIPARPV TVSVFDVLDY RVDSEFYDLD VRVHCSSGTY
     IRALARDLGN ALQVGGHLTA LRRTEVGPFT LNDATPLSKL QENPELSLNL DQALTRSYPV
     LDITEDEGVD LSMGKWLEPR GLKGVHAAVT PSGKAVALIE EKGKRLATVF VAHPNTL
//
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