GenomeNet

Database: UniProt/SWISS-PROT
Entry: UBIE_SYMTH
LinkDB: UBIE_SYMTH
Original site: UBIE_SYMTH 
ID   UBIE_SYMTH              Reviewed;         251 AA.
AC   Q67LE6;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   19-FEB-2014, entry version 63.
DE   RecName: Full=Demethylmenaquinone methyltransferase;
DE            EC=2.1.1.163;
DE   AltName: Full=Menaquinone biosynthesis C-methyltransferase UbiE;
GN   Name=ubiE; OrderedLocusNames=STH2515;
OS   Symbiobacterium thermophilum (strain T / IAM 14863).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales;
OC   Clostridiales Family XVIII. Incertae Sedis; Symbiobacterium.
OX   NCBI_TaxID=292459;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T / IAM 14863;
RX   PubMed=15383646; DOI=10.1093/nar/gkh830;
RA   Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T.,
RA   Morimura K., Ikeda H., Hattori M., Beppu T.;
RT   "Genome sequence of Symbiobacterium thermophilum, an uncultivable
RT   bacterium that depends on microbial commensalism.";
RL   Nucleic Acids Res. 32:4937-4944(2004).
CC   -!- FUNCTION: Methyltransferase required for the conversion of
CC       demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity).
CC   -!- CATALYTIC ACTIVITY: A demethylmenaquinone + S-adenosyl-L-
CC       methionine = a menaquinol + S-adenosyl-L-homocysteine.
CC   -!- PATHWAY: Cofactor biosynthesis; menaquinone biosynthesis;
CC       menaquinone-2 from chorismate: step 8/8.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding
CC       methyltransferase superfamily. UbiE family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AP006840; BAD41500.1; -; Genomic_DNA.
DR   RefSeq; YP_076344.1; NC_006177.1.
DR   ProteinModelPortal; Q67LE6; -.
DR   STRING; 292459.STH2515; -.
DR   EnsemblBacteria; BAD41500; BAD41500; STH2515.
DR   GeneID; 2982351; -.
DR   KEGG; sth:STH2515; -.
DR   PATRIC; 23783202; VBISymThe116959_2509.
DR   eggNOG; COG2226; -.
DR   HOGENOM; HOG000249463; -.
DR   KO; K03183; -.
DR   OMA; QKVEYEN; -.
DR   OrthoDB; EOG6M6JSB; -.
DR   BioCyc; STHE292459:GJMM-2596-MONOMER; -.
DR   UniPathway; UPA00079; UER00169.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01813; UbiE_methyltran; 1.
DR   InterPro; IPR004033; UbiE/COQ5_MeTrFase.
DR   InterPro; IPR023576; UbiE/COQ5_MeTrFase_CS.
DR   Pfam; PF01209; Ubie_methyltran; 1.
DR   TIGRFAMs; TIGR01934; MenG_MenH_UbiE; 1.
DR   PROSITE; PS51608; SAM_MT_UBIE; 1.
DR   PROSITE; PS01184; UBIE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Menaquinone biosynthesis; Methyltransferase;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    251       Demethylmenaquinone methyltransferase.
FT                                /FTId=PRO_0000193339.
SQ   SEQUENCE   251 AA;  28582 MW;  79E95F0D99ADA234 CRC64;
     MAPGYQPPSP EEKEQYVREL FDKIAENYDA MNQVMSAGQW EKWHREFVAQ THFRPGDHIL
     DVACGTGDLT LLDAAQVAPD GKVIGVDISE GMLEVGRRRV AASPYKDLIT LQLGNAMDLP
     FPDNTFDGVT MGWAMRNVAS IPRTLSEIYR VLKPGGRFIC LEASKPFSRF IRFGFFVYWK
     TFLPLIDWFV VKAGRQAKVR PYTYLSRSLD NYPFPDQLEE LFREAGFVET DYQLLMLGTV
     AIHVGTKRRE G
//
DBGET integrated database retrieval system