ID   URK_BORT9               Reviewed;         206 AA.
AC   A1QYG8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 1.
DT   01-MAY-2013, entry version 36.
DE   RecName: Full=Uridine kinase;
DE            EC=2.7.1.48;
DE   AltName: Full=Cytidine monophosphokinase;
DE   AltName: Full=Uridine monophosphokinase;
GN   Name=udk; OrderedLocusNames=BT0015;
OS   Borrelia turicatae (strain 91E135).
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia.
OX   NCBI_TaxID=314724;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91E135;
RA   Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T.,
RA   Schwan T.G.;
RT   "The genome sequence of Borrelia hermsii and Borrelia turicatae:
RT   comparative analysis of two agents of endemic N. America relapsing
RT   fever.";
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + uridine = ADP + UMP.
CC   -!- CATALYTIC ACTIVITY: ATP + cytidine = ADP + CMP.
CC   -!- PATHWAY: Pyrimidine metabolism; CTP biosynthesis via salvage
CC       pathway; CTP from cytidine: step 1/3.
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage
CC       pathway; UMP from uridine: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the uridine kinase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000049; AAX17360.1; -; Genomic_DNA.
DR   RefSeq; YP_945030.1; NC_008710.1.
DR   STRING; 314724.BT0015; -.
DR   EnsemblBacteria; AAX17360; AAX17360; BT0015.
DR   GeneID; 4642818; -.
DR   KEGG; btu:BT0015; -.
DR   PATRIC; 20571723; VBIBorTur92789_0015.
DR   eggNOG; COG0572; -.
DR   HOGENOM; HOG000262756; -.
DR   KO; K00876; -.
DR   OMA; DICFMRR; -.
DR   ProtClustDB; PRK05480; -.
DR   BioCyc; BTUR314724:GJ88-15-MONOMER; -.
DR   UniPathway; UPA00574; UER00637.
DR   UniPathway; UPA00579; UER00640.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0004849; F:uridine kinase activity; IEA:HAMAP.
DR   GO; GO:0044211; P:CTP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00551; Uridine_kinase; 1; -.
DR   InterPro; IPR006083; PRK/URK.
DR   InterPro; IPR000764; Uridine_kinase.
DR   Pfam; PF00485; PRK; 1.
DR   PRINTS; PR00988; URIDINKINASE.
DR   TIGRFAMs; TIGR00235; udk; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    206       Uridine kinase.
FT                                /FTId=PRO_1000200507.
FT   NP_BIND       9     16       ATP (Potential).
SQ   SEQUENCE   206 AA;  23969 MW;  166E8BB6A2451013 CRC64;
     MVKIIGITGG SGSGKTTVVN KISEVIPEFV LISQDNYYKS VGDYEYEFLD VNFDHPDAFD
     NNLFYKHLKK LKENKLIHMP LYDFINHKRK DETVEIVPTP VVIVEGIMIF VEERVRNLID
     LKIYIDTPND IRFIRRLERD MSKRGRTLES VIEQYLSTTR AGYYRFIEPT KEYADLIIPE
     GGHNDKALYV LSSFLRTLGQ ESSVFF
//