KEGG   Streptococcus pyogenes MGAS6180 (serotype M28): M28_Spy0027
Entry
M28_Spy0027       CDS       T00263                                 
Symbol
purH
Name
(GenBank) phosphoribosylaminoimidazolecarboxamide formyltransferase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
spb  Streptococcus pyogenes MGAS6180 (serotype M28)
Pathway
spb00230  Purine metabolism
spb00670  One carbon pool by folate
spb01100  Metabolic pathways
spb01110  Biosynthesis of secondary metabolites
Module
spb_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:spb00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    M28_Spy0027 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    M28_Spy0027 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:spb04147]
    M28_Spy0027 (purH)
Enzymes [BR:spb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     M28_Spy0027 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     M28_Spy0027 (purH)
Exosome [BR:spb04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   M28_Spy0027 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: AAX71141
UniProt: Q48VY9
Position
43845..45392
AA seq 515 aa
MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGVETIAIDDVTGFPEMMD
GRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNLYPFKETILRPDITYDLAV
ENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAGQTTFETRQRLAAKVFRHTA
AYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQ
LNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHMNPCGIGQADDIETAWDYAYEADPV
SIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSYSEEALAILTNKKKNLRILELPFDAQA
ASEVEAEYTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNG
IIITNDHMTLGLGAGQTNRVGSVKIAIEQAKDHLDGAVLASDAFFPFADNIEEIAAAGIK
AIIQPGGSVRDQDSIDAANKHGLTMIFTGVRHFRH
NT seq 1548 nt   +upstreamnt  +downstreamnt
atgactaaacgtgctttaatctcagtgtctgacaagtcaggaattgttgactttgcaaaa
gaattgaaaaacttgggttgggatattatctcaactggtgggactaaggttgcccttgat
aatgctggcgttgagaccattgccatcgacgatgtgactggattcccagagatgatggac
ggtcgtgttaagaccctccacccaaacattcacggtgggcttttggctcgtcgcgacgct
gacagccaccttcaggctgctaaggacaacaatatcgagctgattgacctcgtggttgtc
aacctctatcccttcaaggagactatccttcgtccagatataacctatgatttggcggtg
gaaaacatcgacatcggcggtccatcaatgcttcgctcagccgctaaaaatcacgctagc
gtgaccgttgtggttgacccagcggattatgcgactgttttgggagaattggctgacgct
ggtcagacgacatttgaaacgcgtcaacgcttggcagctaaggtctttcgtcacacagca
gcctacgacgctttgattgctgagtacttcacaactcaagtgggagaggctaagcctgaa
aaattaaccatcacttacgaccttaaacaggctatgcgttacggagaaaatccacaacaa
gacgctgatttctatcaaaaagccttgccaacagactactcaattgcttctgctaaacag
ctcaacggaaaagaattgtccttcaataatatccgtgatgccgatgcagcaatccgtatt
atccgtgatttcaaagatcgtccaactgttgttgtcctcaaacacatgaacccatgtggt
atcggacaggctgatgatattgagacagcttgggattacgcttatgaagctgacccagtt
tcaatctttggtggaattgtcgtccttaaccgtgaagttgacgcagcgacagctaagaag
atgcaccctatcttcttggaaatcatcatcgcaccatcatactcagaagaagcgctagct
attctcacaaataaaaagaaaaacttgcgaatccttgagttgccgtttgatgcccaagct
gccagcgaagtggaagctgagtacactggcgtagttggtggacttttggtgcaaaaccaa
gacgttgtggctgaaaatccatctgactggcaagtggtgacagaccgccaaccaacagaa
caagaggcgactgcccttgagtttgcctggaaggctatcaagtatgttaagtctaacggg
attattattactaacgatcacatgacgcttggactcggtgcaggtcaaaccaaccgtgtc
ggctcagtcaagattgctatcgagcaggctaaagaccaccttgacggtgccgttctagca
tcagatgccttcttcccatttgcggacaacattgaagaaatcgctgccgcagggatcaaa
gcaatcatccaaccaggtggttcagttcgtgaccaagactctattgacgccgcaaacaaa
catggcttgaccatgatcttcacaggtgtgagacattttaggcattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (26)   

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