KEGG   Streptococcus pyogenes MGAS6180 (serotype M28): M28_Spy0551
Entry
M28_Spy0551       CDS       T00263                                 
Symbol
lig
Name
(GenBank) NAD-dependent DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
spb  Streptococcus pyogenes MGAS6180 (serotype M28)
Pathway
spb03030  DNA replication
spb03410  Base excision repair
spb03420  Nucleotide excision repair
spb03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:spb00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    M28_Spy0551 (lig)
   03410 Base excision repair
    M28_Spy0551 (lig)
   03420 Nucleotide excision repair
    M28_Spy0551 (lig)
   03430 Mismatch repair
    M28_Spy0551 (lig)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:spb03032]
    M28_Spy0551 (lig)
   03400 DNA repair and recombination proteins [BR:spb03400]
    M28_Spy0551 (lig)
Enzymes [BR:spb01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     M28_Spy0551 (lig)
DNA replication proteins [BR:spb03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     M28_Spy0551 (lig)
DNA repair and recombination proteins [BR:spb03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     M28_Spy0551 (lig)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     M28_Spy0551 (lig)
   MMR (mismatch excision repair)
    DNA ligase
     M28_Spy0551 (lig)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      M28_Spy0551 (lig)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT HHH_3 NuA4
Other DBs
NCBI-ProteinID: AAX71665
UniProt: Q48UE1
Position
570135..572093
AA seq 652 aa
MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQSYPEYVLQDSPTQQVG
GTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNATYLAELKIDGLSISLSYE
NGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTITVRGEAYMSRQSFKAINEARQ
ENGETEFANPRNAAAGTLRQLDTAVVAKRQLATFLYQEASPTARNQQNEVLAELADLGFS
VNPYYQLTSSMDEIWNFIKTIEAKRDQLAYDIDGVVIKVNSLAMQEELGFTVKAPRWAIA
YKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRIG
DTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIPKLCPSCGSELVHFEDEVALRCINPLCPS
LIQRSLEHFASRDAMNITGLGPAIVEKLFLAGFVHDVADIYQLTKEDFMQLDGIKEKSAD
KLLAAIEASKSNSAEKLLFGLGIRHIGSKVSRLILEVYGDISALLTAKEEEIARIDGLGS
TIAQSLTQYFEQKTAAILVDELKTAGVNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNE
AKDKLEALGAKVTGSVSKKTDLVIAGSDAGSKLEKAKSLGIRIEDEDWLRQL
NT seq 1959 nt   +upstreamnt  +downstreamnt
atgaaaaaacgcataaaagaattaacagatcttcttaaccgttaccgttatgactattat
actaaagatgccccatcagtttctgacagtgactatgataagctttatcgtgaactggtg
actttagagcagtcatatcccgagtatgtcttgcaagatagcccaacgcagcaggttgga
gggactattttaaaggggtttgaaaaatatcgacatcagtatccgctttttagtttgcag
gatgctttttcacgtgaggagctggatgcttttgataagcgcgtcaaggccgaatttccg
aatgccacctatctagcagagttaaaaattgatggtttatctatttccttgagttatgag
aatggcttcttacaggttggagcaacacggggtgatggcaatatcggtgaaaatatcaca
gaaaatattaaaaaaataaaggatattcctcaccaattgagtgagcctttaaccatcacc
gttcgaggagaggcttacatgtctcgtcagtcctttaaagcgatcaatgaagcacgccaa
gaaaatggggagactgaatttgctaatcctagaaatgctgccgctgggacactaaggcag
ctagatacggcagtggttgctaagcgtcaactagccacttttttgtatcaagaagctagt
ccgacagctagaaatcaacaaaatgaggtcttagcagaattagcagatctaggtttttca
gtaaatccgtattatcaactcacatcgtctatggatgagatttggaattttatcaaaact
attgaggcaaaaagagatcaattagcttatgacatagatggcgttgttattaaagttaat
agcctagccatgcaagaagagctagggtttacggttaaagctccacgctgggctattgct
tacaaatttccagcagaagaaaaagaggcagaaatcctttcggttgactggacagtggga
cgaacaggcgtggtcacacctacagcgaatctaactcctgtgcaactagcggggacaacc
gtgagtcgtgcaaccctacataatgtggattatattgccgaaaaagatatccgtattggc
gatacagtgattgtatataaggcaggggacattattcctgctgtcttaaatgtcgttatg
agtaagcggaaccagcaagaagtcatgcttattcctaaactatgcccatcttgtggtagt
gaattagttcattttgaagatgaggttgctttgcgttgtattaatccgttgtgtcctagt
ttgattcagcgaagtttggagcattttgcaagtcgtgatgccatgaacattactgggctg
ggaccagctattgtggaaaaactatttttagcggggtttgttcatgatgttgctgatatt
taccagttgaccaaagaagatttcatgcaattagatggcatcaaagaaaagtcagctgat
aaattgctcgctgcgattgaggcttctaaatcaaattcagctgaaaaactgttatttggt
ctaggaattcgtcatattggctctaaggttagtcgcttaattttagaggtatacggagat
atttctgctcttttaaccgctaaagaagaggaaatcgcaaggatagatggtcttggctca
acgattgctcaatcacttactcaatactttgaacaaaaaacggctgcgattttagtagac
gagttaaagacagcaggtgtcaacatgcattactcaggtcaaaaagttaatagtgacgca
gcgctttttggtctaactgttgttttaactggcaaattaaatcagctgaaccgaaatgag
gccaaagataaattagaggcattaggtgccaaagttactggaagtgtatctaagaaaaca
gatttagttattgcaggtagtgacgctggttctaagctagaaaaagcaaagagcttagga
attcggattgaagatgaagattggctacgccagctttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (9)   
   Pfam (9)   
All databases (30)   

Download RDF
DBGET integrated database retrieval system