KEGG S.pyogenes_MGAS10270: MGAS10270

Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy1840

Entry

MGAS10270_Spy1840 CDS S.pyogenes_MGAS10270

Gene name fhs2

Definition formate--tetrahydrofolate ligase (EC:6.3.4.3)

Orthology K01938 formate--tetrahydrofolate ligase [EC:6.3.4.3]

Pathway sph00630 Glyoxylate and dicarboxylate metabolism
sph00670 One carbon pool by folate
sph01100 Metabolic pathways

Class Metabolism; Carbohydrate Metabolism; Glyoxylate and dicarboxylate
metabolism [PATH:sph00630]
Metabolism; Metabolism of Cofactors and Vitamins; One carbon pool by
folate [PATH:sph00670]

SSDB

Motif Pfam: FTHFS
PROSITE: FTHFS_2 FTHFS_1

Other DBs NCBI-GI: 94991349
NCBI-GeneID: 4063544
UniProt: Q1JEK4

Position 1797410..1799083

AA seq 557 aa
MVLSDIEIANSVSMEPISKVADQLGIDKEALCLYGKYKAKINARQLVALKDKPDGKLILV
TTISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLK
AGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACNKRGVDVVISDVWANGGAGGRE
LAEKVVTLAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGITLTPAAKRELADLERLGF
GNYPICMAKTQYSFSDDAKKLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF

NT seq 1674 nt +upstreamnt +downstreamnt
atggttttatcagatattgaaatagccaactctgtctctatggaacctatcagtaaggtt
gccgatcaattagggatcgacaaggaagcgctctgtctctatggtaagtacaaggcaaaa
attaatgcccgtcaactggtcgccttaaaagacaaacctgatggcaaactcattcttgtc
actactatctcaccaacaccagctggtgaaggcaaaaccaccacttccgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttagctgccttgattgataaccacattcaccatggcaatagcctaggcattgattccaga
cgtattacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgac
ggcttgcaaggcaaggtcaacggggtccctcgtgaggatggttacgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatttctgacctcaaagcccgcctt
gaaaaaatcatcatcggttacaactatcaaggcgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagccgcactgctcaaggatgcgattcatcctaatctcgtgcaaacc
ctggaacacacaccagccctcattcacggtggcccatttgctaatatcgcccatggctgt
aatagtgtcctagccaccaaactagccttgaaatatggtgattatgccgttaccgaagct
ggatttggtgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtccggc
cttcgtccagcagccgttgtcctagtagccactattcgtgcccttaaaatgcatgggggt
gtgccaaaagcagacctggctactgaaaatgttcaggccgttgtggatggtttacctaac
cttgacaaacatttggctaatatccaagacgtctatggccttccagttgtcgtggcgatc
aataaattcccgcttgataccgatgctgaattacaagctgtctatgatgcctgcaacaaa
cgtggcgttgacgttgtgatttctgatgtttgggcaaatggcggagctggtggccgtgaa
ttagctgaaaaagtcgtgacactagccgagcaagacaatcaattccgctttgtttatgag
gaagacgatagcattgaaaccaaactgactaaaatcgttaccaaggtttacggtggtaaa
ggcatcaccttgacccccgcagccaaacgtgaactggctgacttagaacgcctcggcttt
ggcaactacccaatttgcatggccaaaacccaatattccttctcagacgatgccaaaaaa
cttggcgcaccaactgactttacagtgactattagcaacctcaaagtgtccgcaggagca
ggatttatcgttgctctgacgggtgctatcatgaccatgcctggccttccaaaagtacct
gccagcgaaaccattgatattgacgaggagggcaacatcacaggactattctaa

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (1)   
   PROSITE (2)   
All databases (16)

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