KEGG   Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy0023
Entry
MGAS9429_Spy0023  CDS       T00358                                 
Name
(GenBank) phosphoribosylformylglycinamidine synthase
  KO
K01952  phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
Organism
spk  Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00230  Purine metabolism
spk01100  Metabolic pathways
spk01110  Biosynthesis of secondary metabolites
Module
spk_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:spk00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    MGAS9429_Spy0023
Enzymes [BR:spk01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.3  phosphoribosylformylglycinamidine synthase
     MGAS9429_Spy0023
SSDB
Motif
Pfam: GATase_5 AIRS_C FGAR-AT_linker GATase_3 DJ-1_PfpI GATase Svf1_C
Other DBs
NCBI-ProteinID: ABF31211
UniProt: Q1JP38
Position
36471..40244
AA seq 1257 aa
MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIESLPGQFDQRAVSSQEAL
LLFGSDSQVKVNTAQFYLVNKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSVSDK
TIPNLDFFETYKADDFTAYKVEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSD
HCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGA
IRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGYSSYGNQIGLATT
YVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSK
VQTVESVETAGAEVQKGNAIEERKIQRLFRAGNVTRLIKKSNDFGAGGVCVAIGELADGL
EIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNDETIVDLERRFLDTNGVRVVVDAKVVDKDLTVPEARITSAETLEADTLKVLS
DLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTTTASVMAQGY
NAYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALL
GSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVTTADSRKILSPEFKAAGENIYY
IPGQAISEDIDFDLIKANFSQFEAIQTQHKITAASAVKYGGVLESFALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVTVNGNDLAGASLLAAFEGKLEE
VYPTEFEQTDVLEEVPAVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASV
NLVPFVTLNEVAIAESVDTMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRA
AIDSFIEKGGLIIGICNGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRI
ANTNSPWLAGVEVGDIHAIPVSHGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK
NT seq 3774 nt   +upstreamnt  +downstreamnt
atgtcctcctattttccagtcgctcccttgtcggacttggtatcttatatgaataaacgt
atttttgttgagaaaaaggctgactttggtattaaatcggctagccttgtgaaagagttg
acgcataatctacaactgacttctttgaaggctttgcgtattgtgcaggtctatgatgtc
ttcaatttggctgaggatttgctggcgcgtgctgagaagcatattttctctgagcaggtg
acagactgtcttttgacggaaactgaaatcactgcggagcttgataaggttgccttcttt
gccattgagtcgcttcctggtcaatttgaccaacgtgctgttagttcgcaagaagctttg
ctattatttggaagtgacagtcaggttaaggtcaatacagcccagttttacttggtcaat
aaggatattgcagaagcagagcttgaagccgttaagaactatcttttgaaccctgttgat
tcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctgtgtctgataag
acgatccctaatcttgatttcttcgagacttataaggctgacgattttacggcttataag
gtagagcagggcttggctatggaggtcgatgatcttctcttcatccaagattatttcaaa
tcaatcgggcgtgtgccaactgagactgagttgaaagttttggatacgtattggtcagac
cactgtcgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttctaaa
ttccaaaaacaattgcagacaacttatgacaaatatatcgccatgcgtgatgagcttggt
cgttctgaaaagccacaaacacttatggatatggcgactatttttggtcgttatgagcgt
gccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagttgag
attgaagtagatgttgatggtgtgaaagagccttggctcctcatgtttaagaatgagaca
cacaatcacccaacagaaattgagccattcggtggagcggcgacttgtatcggtggtgct
attcgtgacccattgtcaggacgttcatacgtttatcaggctatgcgtatttcaggcgca
ggcgatatcacgactccgattgcggaaacacgtgctggtaaattgccacaacaggttatt
tctaagactgcggcgcacggctattcttcatatggtaaccaaattggacttgcgacaact
tatgtgcgtgagtacttccaccctggcttcgtagccaaacgtatggagcttggagctgtg
gttggtgctgcacctaaggaaaatgtggttcgtgaaaaaccagaagcaggtgatgtggta
atcttgcttggtggtaaaacagggcgtgacggtgtcggcggtgcgacaggttcatctaag
gttcaaacggttgaatctgtggaaacagcaggagcagaggtacaaaaagggaatgccatc
gaagagcgtaagattcaacgtcttttccgtgctggcaatgtcactcgtctgatcaagaaa
tcaaatgacttcggtgcaggtggtgtctgtgttgccatcggtgaattggctgacggtctt
gaaatcgatttggacaaggtgcctcttaaataccaaggtcttaatggtactgaaattgca
atctcagaatctcaagagcgtatgtcagtcgttgttcgtccaagtgatgtggatgccttc
atcgcagcctgcaacaaggaaaatatcgatgcagtcgtagttgcgactgtgactgaaaaa
ccaaatcttgtcatgacttggaatgatgaaacaattgttgatttggaacgccgtttcctt
gataccaatggtgtccgtgtcgttgttgatgctaaagtcgttgacaaggacttgacagtt
ccagaagcacgcataacatcagcagagacacttgaagcagatacgcttaaggtcttgtct
gacctcaaccatgctagtcaaaaaggtctccaaaccatctttgactcatctgttggtcgt
tcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttctgtt
caaaaattgccagttcaacatggtgtgacaacaactgcatctgttatggctcaaggttac
aatgcttatattgcagagtggtcaccttatcacggtgctgcctatgctgttattgaagcg
acagctcgcttggtagcaacaggtgctgactggtctcgtgcacgtttctcttaccaagag
tatttcgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctcttctt
ggttctattgaggctcagattcaacttggcttgccatcaatcggtggtaaggactctatg
tctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggtgtgacaaca
gcggacagccgcaagattctctctcctgagtttaaagcggctggtgagaatatctactac
attccaggtcaagctatttcagaagatattgattttgaccttatcaaggctaacttcagt
cagtttgaagctattcaaactcaacataagattacagctgcctcagccgttaaatacggt
ggtgtcctagaaagttttgctctcatgacttttggtaaccgtatcggtgcttctgttgaa
attgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatcagct
gaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagactttacagtcactgtc
aatggaaatgaccttgctggcgctagccttctagcagccttcgaaggcaaattggaagag
gtttacccaacagaatttgaacagacagatgttcttgaagaagttcctgctgtggtatca
gatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattccagtcttc
cctggtaccaactcagagtacgattcagctaaggcctttgaacaggttggagctagtgtc
aacttggtaccatttgtaaccttgaatgaggttgctattgctgagtcagttgacactatg
gttgctaatattgctaaggcaaatatcatcttctttgctggaggtttctcagcagcggat
gaaccagatgggtctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgcgca
gctattgacagcttcatcgaaaaaggtggccttatcatcggtatctgtaatggtttccaa
gcccttgttaaatcaggtcttcttccatacggaaacttcgaggaagctggtgagacaagt
ccaactctcttctataacgatgctaatcagcatgttgccaagatggttgagactcgtatc
gcaaataccaactcaccttggttggcaggagttgaggtcggcgatattcatgccattcca
gtttcacatggtgaaggtaaatttgttgtcagcgcttctgaatttgcagagctaagagac
aatggtcaaatctggagccaatatgtggactttgacggacaaccatctatggattctaaa
tacaatccaaacggctctgtcaatgccatcgaagggattaccagcaagaatggtcaaatc
atcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatattcctggt
aacaaagaccaaaccctctttgcaagtgctgtaaaatactttacagggaagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (7)   
   Pfam (7)   
All databases (28)   

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