KEGG   Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy0939
Entry
MGAS9429_Spy0939  CDS       T00358                                 
Symbol
folC1
Name
(GenBank) folylpolyglutamate synthase
  KO
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Organism
spk  Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00790  Folate biosynthesis
spk01100  Metabolic pathways
spk01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:spk00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    MGAS9429_Spy0939 (folC1)
Enzymes [BR:spk01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     MGAS9429_Spy0939 (folC1)
    6.3.2.17  tetrahydrofolate synthase
     MGAS9429_Spy0939 (folC1)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C
Other DBs
NCBI-ProteinID: ABF32126
UniProt: Q1JLU3
Position
898933..900309
AA seq 458 aa
MFGEDNKKKGTTLGYLLSLFFIYGILKIDVRCEMTYEETLEWIHDHLVFGIKPGLKRMLW
VLGQLGNPQKNVKGVHIVGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISING
RMISEKDLVIAANRIRPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGL
GGLYDSTNVFQAMVVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSARE
VFLTKAEQVGASIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMT
CLTLKDRYPRLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYND
KKLHILFGAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPLEKYPERFGRVADFKDFLAL
RKHAKADDFFVITGSLYFISEIRQYWKKHIEKNVLLTH
NT seq 1377 nt   +upstreamnt  +downstreamnt
gtgtttggtgaggataataaaaaaaagggtactactctaggttatctgctgtcacttttt
tttatatatggtatactaaagatagatgtgaggtgtgaaatgacttatgaagagactcta
gaatggattcatgatcacttagttttcggcatcaagccaggcttaaaacgtatgctttgg
gttcttggacagttaggaaatccccaaaaaaatgtcaagggagtgcatatcgttggaact
aacggaaaaggttccacggtcaatcatttacaacacatttttacgacagctggttatgaa
gtggggacctttacctctccttatattatggatttcaaagaacgtattagcataaatggt
cgaatgatttcagaaaaagatttggttattgctgctaatcgtattcgtcctttgacagag
cgtctagttcaagagactgattttggagaggtaactgaatttgaagtgattactttgatc
atgttcctctattttggagacatgcatcctgtagatattgctattattgaagcaggcctt
ggcggtctttatgattcgaccaatgtttttcaagcaatggttgtggtatgtccctcaatt
ggtttagatcaccaagctattttgggagagacttacgctgatattgccgcccaaaaagct
ggtgttttagaagggggcgagacccttgtttttgccgttgaaaacccgtcagctcgagag
gtttttttaacaaaagctgagcaggttggtgcttcaatctgggaatggcaagagcagttt
caaatggctgagaacgcatctggctatcgttttactagtcctttaggagttatttcagat
attcacatcgctatgccaggacaccaccaagtgtctaatgcagctttagctattatgact
tgcttaaccttgaaagaccgctatcctaggctaacttcagatcatataagggaaggtctg
gcaaatagtttgtggctaggccgtaccgaattattagcaccaaatctaatgattgatggg
gctcataacaatgaaagcgttgctgctttggtagccgtcttaaaaaataactacaatgat
aaaaagcttcatattttgtttggtgcgatcgacaccaagcctattgcggatatgttggtt
gctcttgagcaaataggtgacttgcaggttactggctttcattaccctaacgcctatcca
ttggaaaaatacccagaacgttttggtagggttgctgatttcaaagatttcttggccctg
cgtaagcatgccaaagcagatgactttttcgtgattacagggtcgctatattttatttca
gaaattagacagtattggaaaaaacatattgaaaaaaacgttcttttaacccattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (28)   

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