KEGG   Streptomyces pluripotens: LK06_013375
Entry
LK06_013375       CDS       T04845                                 
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
  KO
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
splu  Streptomyces pluripotens
Pathway
splu00860  Porphyrin metabolism
splu01100  Metabolic pathways
splu01110  Biosynthesis of secondary metabolites
splu01120  Microbial metabolism in diverse environments
splu01240  Biosynthesis of cofactors
Module
splu_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
splu_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:splu00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    LK06_013375
Enzymes [BR:splu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     LK06_013375
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     LK06_013375
SSDB
Motif
Pfam: HEM4 TP_methylase
Other DBs
NCBI-ProteinID: ARP70789
UniProt: A0A221NZ01
Position
complement(3002630..3004339)
AA seq 569 aa
MSPTTLPAAGPEHGHVTFLGAGPGDPGLLTLRAVEALSNADVLVAEHEVLDVIRTHARQG
VSVVQTDADPSSGPLPGTGTPQLAVVDGTSKTAAVPVVRDAAHLVMEAARGGRRVVRAVS
GDPGLDTYAAEEMLACASAGVPFEVVPGVAAAVGVPAYAGVPLRDAEGTDVRFVDARTAS
DRCWTEVGASDGTVVVSTTLDAVAAAAGELVSAGRKPDTPLSVTVAGTTTRQRTWTATLG
TIAQTLKQAKVLPSPDGGRPVIAVVGERSAAARRDQLSWFESKPLFGWKVLVPRTKEQAA
SLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKF
EEYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPI
DRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTS
SSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHRLAEALAEFGAK
RRAAALEAGDPVTRPSERRPGARRRRSTT
NT seq 1710 nt   +upstreamnt  +downstreamnt
ttgagccccaccacccttcccgccgccggtccggaacacgggcacgtcaccttcctgggt
gccggacccggagatccgggactgctcactctgcgcgccgtggaggcgctgtcgaacgcg
gatgtcctggtcgccgagcacgaggtgctcgacgtgatccggacgcacgcacgacagggc
gtctccgtcgtgcaaacggacgcggatccttcctcgggcccgcttccgggcacgggcacg
ccccagctggcggtcgttgacggcacgtcaaaaaccgccgctgtcccggtggtgcgggat
gccgcccatcttgtcatggaggctgcccggggcggcaggcgggtcgtccgtgcggtgtcc
ggggacccgggactagatacgtacgcggccgaggaaatgctcgcctgcgcctccgccggg
gtgcccttcgaggtcgttcccggcgtcgcggcggcggtcggcgtgccggcctacgccggt
gtgccgctgcgggacgccgagggcacggacgtccggttcgtggacgcccgtaccgcttcc
gaccgctgctggacggaggtgggcgcctcggacggcacggtcgtcgtctccaccaccctg
gacgcggtggccgccgccgcgggcgaactggtgtccgcgggccgcaagccggacaccccg
ctgtcggtcaccgtcgccggtacgacgacccgtcagcgcacctggacggccacgctcggc
acgatcgcgcagacgctgaagcaggccaaggtgctgccgtcgccggacggcggccggccg
gtgatagccgtggtcggtgagcgctccgccgccgcccggcgtgaccagctctcgtggttc
gagtccaagccgctgttcggctggaaggtgctcgtgccgcgcacgaaggagcaggcagcg
tcgctctccgaccagctgcgctcctacggcgcggtgccgcacgaggtgccgacgatcgcc
gtcgagccgccgcgcacgccccagcagatggaacgtgccgtcaagggtctggtgacgggc
cgctacgagtggatcgccttcacgtccgtcaacgcggtcaaggcggtccgggagaagttc
gaggagtacggcctcgacgcccgggccttcgcgggcatcaaggtggccgcggtgggcgag
cagaccgccaaggcgctcatcgccttcggcgtgaagccggacctggtgccgagcggcgag
cagtcggccgccggtctgctggaggactggccgccctacgacccggtcttcgacccgatc
gaccgcgtcttcctgccccgcgccgacatcgccaccgagaccctcgtcgccggcctgatc
gagctgggctgggaggtcgacgacgtcaccgcgtaccggaccgtacgggcctcgccgccc
ccggccgagacacgggaggcgatcaagggcggcggcttcgacgccgtgctcttcacgtcc
tcgtccacggtgcggaacctggtgggcatcgccggcaagccgcacaacgtgacggtgatc
gcctgcatcggcccggccacggccaagaccgccgaggaacacggtctgcgggtcgacgtc
atggctccggagccgtccgtgcaccggctggcggaggcgctggccgagttcggcgccaag
cggcgtgccgccgcgctggaggccggggacccggtcacccggcccagcgagcgccggccg
ggggcgcggcgacggcggtcgacgacctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (5)   
   KEGG MODULE (5)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (29)   

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