Database: SPTrEMBLEntry: TMOE_PSEME
LinkDB: TMOE_PSEME
Original site: TMOE_PSEME
ID TMOE_PSEME Reviewed; 327 AA.
AC Q00460;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 24-NOV-2009, entry version 45.
DE RecName: Full=Toluene-4-monooxygenase system protein E;
DE EC=1.14.13.-;
GN Name=tmoE;
OS Pseudomonas mendocina.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=300;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-15.
RC STRAIN=KR1;
RX MEDLINE=91358306; PubMed=1885512;
RA Yen K.-M., Karl M.R., Blatt L.M., Simon M.J., Winter R.B.,
RA Fausset P.R., Lu H.S., Harcourt A.A., Chen K.K.;
RT "Cloning and characterization of a Pseudomonas mendocina KR1 gene
RT cluster encoding toluene-4-monooxygenase.";
RL J. Bacteriol. 173:5315-5327(1991).
CC -!- FUNCTION: Hydroxylates toluene to form p-cresol.
CC -!- COFACTOR: FAD.
CC -!- COFACTOR: Fe(2+).
CC -!- PATHWAY: Xenobiotic degradation; toluene degradation.
CC -!- SUBUNIT: The multicomponent enzyme toluene-4-monooxygenase is
CC formed by the tmoA, tmoB, tmoC, tmoD, tmoE and tmoF polypeptides.
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DR EMBL; M65106; AAA26003.1; -; Genomic_DNA.
DR PDB; 3DHG; X-ray; 1.85 A; B/E=1-327.
DR PDB; 3DHH; X-ray; 1.94 A; B=1-327.
DR PDB; 3DHI; X-ray; 1.68 A; B=1-327.
DR PDB; 3GE3; X-ray; 1.52 A; B=1-327.
DR PDB; 3GE8; X-ray; 2.19 A; B/F=1-327.
DR PDB; 3I5J; X-ray; 1.90 A; B=1-327.
DR PDB; 3I63; X-ray; 2.09 A; B=1-327.
DR PDBsum; 3DHG; -.
DR PDBsum; 3DHH; -.
DR PDBsum; 3DHI; -.
DR PDBsum; 3GE3; -.
DR PDBsum; 3GE8; -.
DR PDBsum; 3I5J; -.
DR PDBsum; 3I63; -.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016709; F:oxidoreductase activity, acting on paired d...; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR InterPro; IPR009078; Ferritin/RR-like.
DR InterPro; IPR012078; MP_mOase_hydro.
DR InterPro; IPR003430; Phenol_Hydrox.
DR InterPro; IPR012348; Ribncl_red_rel.
DR Gene3D; G3DSA:1.10.620.20; Ribncl_red_rel; 1.
DR Pfam; PF02332; Phenol_Hydrox; 1.
DR PIRSF; PIRSF000040; MMOH_comp; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Aromatic hydrocarbons catabolism;
KW Direct protein sequencing; FAD; Flavoprotein; Iron; Monooxygenase;
KW Oxidoreductase.
FT INIT_MET 1 1 Removed.
FT CHAIN 2 327 Toluene-4-monooxygenase system protein E.
FT /FTId=PRO_0000072603.
FT TURN 13 17
FT HELIX 24 29
FT HELIX 34 36
FT STRAND 42 45
FT HELIX 50 58
FT TURN 59 61
FT HELIX 69 71
FT HELIX 80 87
FT HELIX 91 103
FT HELIX 106 109
FT HELIX 115 121
FT TURN 122 124
FT HELIX 125 142
FT HELIX 146 176
FT HELIX 186 192
FT HELIX 200 206
FT HELIX 215 220
FT HELIX 223 230
FT HELIX 232 241
FT HELIX 246 272
FT HELIX 278 282
FT HELIX 286 305
SQ SEQUENCE 327 AA; 38386 MW; 65C53BDFF57E040D CRC64;
MSFESKKPMR TWSHLAEMRK KPSEYDIVSR KLHYSTNNPD SPWELSPDSP MNLWYKQYRN
ASPLKHDNWD AFTDPDQLVY RTYNLMQDGQ ESYVQSLFDQ FNEREHDQMV REGWEHTMAR
CYSPLRYLFH CLQMSSAYVQ QMAPASTISN CCILQTADSL RWLTHTAYRT HELSLTYPDA
GLGEHERELW EKEPGWQGLR ELMEKQLTAF DWGEAFVSLN LVVKPMIVES IFKPLQQQAW
ENNDTLLPLL IDSQLKDAER HSRWSKALVK HALENPDNHA VIEGWIEKWR PLADRAAEAY
LSMLSSDILH AQYLERSTSL RASILTV
//
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