KEGG   Sus scrofa (pig): 100145903Help
Entry
100145903         CDS       T01009                                 

Gene name
PRKAA1, AMPK, AMPK1
Definition
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
ssc  Sus scrofa (pig)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    100145903 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    100145903 (PRKAA1)
   04152 AMPK signaling pathway
    100145903 (PRKAA1)
   04150 mTOR signaling pathway
    100145903 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    100145903 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100145903 (PRKAA1)
   04920 Adipocytokine signaling pathway
    100145903 (PRKAA1)
   04921 Oxytocin signaling pathway
    100145903 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    100145903 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100145903 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100145903 (PRKAA1)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100145903 (PRKAA1)
Protein kinases [BR:ssc01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   100145903 (PRKAA1)
Mitochondrial biogenesis [BR:ssc03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100145903 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    100145903 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
Un
AA seq 550 aa AA seqDB search
MATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVV
GKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRR
LFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPN
YAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLN
PSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCE
KFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTR
PHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIK
QLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTA
TPQRSGSVSNYRACQRNDSDAEAQGKSSEASLTSSVTSLDSSPVDLTPRPGSHTIEFFEM
CANLIKILAQ
NT seq 1653 nt NT seq  +upstreamnt  +downstreamnt
atggcgacagccgagaagcagaaacacgacgggcgggtgaaaatcggccactacatcctg
ggggacacgctgggggtcgggaccttcggcaaagtgaaggttggcaaacatgaattgact
ggtcataaagttgctgtgaagatactcaatcgacagaagattcgaagccttgatgtagta
ggaaaaatccgcagagaaattcagaacctcaagcttttcaggcatcctcatataattaaa
ttgtaccaggtcatcagtacaccatctgatattttcatggtgatggaatatgtttcagga
ggcgagctatttgattatatctgtaaaaatggaaggctggatgaaaaagaaagtcgacgt
ctcttccaacaaatcctttctggtgtggattattgtcacaggcatatggtggtccacaga
gatttgaaacctgaaaatgtcctgcttgatgcacacatgaatgcaaaaatagctgacttc
ggtctttcaaacatgatgtcagatggtgaatttttaagaacgagttgtggctcacccaac
tatgctgcaccagaagtaatttcaggaaggttgtatgctggtccagaggtagatatatgg
agcagtggggttattctctatgctttattatgtggaacacttccatttgatgatgatcat
gtgccaactctttttaagaagatttgtgatgggatcttttatacccctcagtatttaaat
ccttctgtgattagccttttgaaacatatgctacaggtggatcccatgaagagagccaca
atcaaagatatcagggaacatgaatggtttaaacaggaccttccaaaatatctctttcct
gaggatccatcgtatagttcaaccatgattgatgatgaagccttaaaagaagtatgtgaa
aaatttgaatgctcagaagaggaggttctcagctgcctttataacagaaatcaccaggac
cctttggcagttgcctaccaccttataatagataacaggagaataatgaatgaggccaaa
gatttttacttggcaacaagcccacctgattcttttcttgatgatcaccatttgactcgg
ccccatcctgaaagagtaccgtttttggttgctgaaactccaagggcacgccataccctt
gatgaattaaatccacaaaaatccaaacaccaaggtgtaaggaaagcaaaatggcatttg
ggaattagaagtcaaagtcgacccaatgatatcatggcagaagtttgtagagcaattaaa
caactggattatgagtggaaggttgtaaatccatattatttgcgtgttcgaaggaagaat
cctgtgacaagtacatactccaaaatgagtctacaattataccaagtggatagtaggacg
tacttattggatttccgtagtattgatgatgaaattactgaagccaaatcagggactgct
actccacagagatcgggctcagttagcaactatcgagcttgccaaaggaatgattcagat
gctgaggctcaaggaaaatcctcagaagcttctcttacctcatctgtaacctcacttgac
tcttctcctgttgacttaactccaagacctggaagtcacacaatagaattttttgagatg
tgtgcaaatctaattaaaattcttgcacagtaa

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