KEGG   Sus scrofa (pig): 100152497Help
Entry
100152497         CDS       T01009                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
ssc  Sus scrofa (pig)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100152497 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100152497 (PLCG1)
   04015 Rap1 signaling pathway
    100152497 (PLCG1)
   04012 ErbB signaling pathway
    100152497 (PLCG1)
   04370 VEGF signaling pathway
    100152497 (PLCG1)
   04064 NF-kappa B signaling pathway
    100152497 (PLCG1)
   04066 HIF-1 signaling pathway
    100152497 (PLCG1)
   04020 Calcium signaling pathway
    100152497 (PLCG1)
   04070 Phosphatidylinositol signaling system
    100152497 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100152497 (PLCG1)
   04660 T cell receptor signaling pathway
    100152497 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    100152497 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    100152497 (PLCG1)
   04670 Leukocyte transendothelial migration
    100152497 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100152497 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100152497 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100152497 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100152497 (PLCG1)
   05206 MicroRNAs in cancer
    100152497 (PLCG1)
   05205 Proteoglycans in cancer
    100152497 (PLCG1)
   05214 Glioma
    100152497 (PLCG1)
   05223 Non-small cell lung cancer
    100152497 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100152497 (PLCG1)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100152497 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
17
AA seq 1288 aa AA seqDB search
AASPCPNGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWS
RGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQ
ATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQ
VNYRVPNMRFLRERLTELEQRSSDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGER
PELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEETYFFLDEFVTFLF
SKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRC
IELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQR
NMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSE
NDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASSSTE
LHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNG
KVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAH
ESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQT
VMLGNSEFDSLVDLVSYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFY
VEANPMPTFKCAVKALFDYKAQRDDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPS
NYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMAS
VAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPV
PFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNY
DPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLR
GLEPCAICVEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVWPAK
LFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELA
SLLIKLDIFPVKQENSDLSPFGGTSLRERGYDISGQPAHGRAREGSFEARYQQPFEDFRI
SQEHLADHFDSRERRAPRRTRVNGDNRL
NT seq 3867 nt NT seq  +upstreamnt  +downstreamnt
gccgcgtccccctgccccaatggatgcgggccgggcgcaccctcggacgccgaggtgttg
cacctctgccgcagcctcgaggtgggcaccgtcatgactttgttttactccaagaagtcg
cagcggcccgaacggaagaccttccaggtcaagctggagacgcggcagatcacgtggagc
cgtggcgccgacaagatcgagggggccattgacattcgcgaaatcaaggagatccgccca
gggaagacctcccgggactttgatcgataccaagaggatcctgcttttcgaccagaccag
tcacactgctttgtcatcctgtatggaatggaattccgcttgaagaccctgagtctgcag
gctacctctgaggacgaagtgaacatgtggatcaagggcttgacttggctgatggaggac
acgctgcaggcggccacgcctctgcagattgagaggtggctgcggaagcagttctactca
gtggaccggaatcgtgaggatcgtatatcagccaaggatctgaagaacatgctgtcccag
gtcaactaccgggtccccaacatgcgcttcctccgagagcggctgacggagctggagcag
cgcagcagcgacatcacctacggacagtttgcacaactgtaccgcagcctcatgtacagc
gcccagaagacgatggacctccccttcctggaagccagtaccctaagggcaggggagcgg
ccagagctctgccgggtgtcccttcctgagttccagcagttcctcctcgagtaccagggg
gagctgtgggctgtcgaccggctccaggtgcaggagttcatgctcagcttcctccgagac
cccttgcgagagatagaggagacttacttcttcctggacgagtttgtcaccttcctgttc
tccaaggagaacagcgtgtggaactcgcagctggatgccgtgtgcccagacaccatgaac
aaccccctttcccactactggatctcctcctctcacaacacgtacctgaccggggaccag
ttctccagcgagtcctccctggaagcctacgcccgctgcctgcggatgggctgccgctgc
attgagttggactgctgggacggcccagacgggatgccggtcatttaccatggacacact
ctgaccaccaagatcaagttctcagacgtcctgcacaccatcaaggagcacgcctttgtg
gcctcagagtacccggtcatcctgtccatcgaggaccactgcagcattgcccagcagagg
aacatggcccagtatttcaagaaggtgctcggggacacgctcctcaccaagcccgtggac
atcgcggccgacgggctcccctcacccaatcagctcaagaggaagatcctcatcaagcac
aagaagctggctgagggcagtgcgtatgaggaggtgcctacgtctgtgatgtactctgag
aacgacatcagcaactccatcaagaacggcatcctctacctggaggaccctgtgaaccac
gagtggtatccccactactttgttctgaccagcagcaagatctactactcagaggagacc
agcagtgaccagggcaacgaggatgaggaggagcccaaggaggcgagcagcagcacagag
ctgcattccaatgagaagtggttccacgggaagctcggggcggggcgggacggccggcac
atcgccgagcgcctgctcacagagtactgcatcgagaccggagccccggacggctccttc
ctcgtgcgcgagagtgagaccttcgtgggtgactacaccctctccttctggcggaacggg
aaagtccagcactgccggatccactcccggcaggacgctgggacccccaagttcttcctg
acagacaacctcgtcttcgactcactctacgacctcatcacacactaccagcaggtgccc
ctgcgctgcaacgagtttgagatgcgcctctctgagccggtcccgcagaccaacgcccac
gagagcaaagagtggtaccacgcgagcctgaccagagcgcaggccgagcacatgctgatg
cgcgtgccccgggacggggccttcctggtgcggaaacgcaatgagcccaactcctacgcc
atctccttccgggctgagggcaagatcaagcattgccgtgtccagcaggagggccagact
gtgatgctgggcaactcggagtttgacagcctcgtggatcttgtcagctactatgagaag
cacccgctgtaccgcaagatgaagctgcgctatcccatcaacgaggaggcattggagaag
atcggcacagctgagcctgactacggggccctgtatgagggccgcaaccctggcttctac
gtggaggccaaccctatgccgactttcaagtgtgccgtcaaagcgctcttcgactacaag
gcccagagagatgacgagctgaccttcaccaagagcgccatcatccagaacgtggagaag
caggagggaggctggtggcggggggactatggtgggaagaagcagctgtggtttccgtcc
aactacgtggaagagatggtcagccctgcggccctggagcccgagagggagcacttggac
gagaacagccccctgggggacttgctgcggggggtcttggatgtgccagcctgtcagata
gccatccgtcctgagggcaagaacaacaggctcttcgtcttctccatcagcatggcgtcg
gtggcacattggtccttggatgtggctgctgactcacaggaggagctgcaggactgggtg
aaaaagatccgagaggtggcccagaccgcggatgccaggctcacagaggggaagatgatg
gagcggaggaagaaaatcgccttggagctttctgagctcgtcgtctactgccggcctgtt
cccttcgatgaagagaagatcggcacagaacgcgcctgctaccgggacatgtcgtccttc
ccggaaaccaaggctgagaagtatgtgaacaaggccaaaggcaagaagttcctccagtac
aaccggctgcagctgtcgcgcatctaccccaagggccagcggctggactcctccaattat
gaccccttgcccatgtggatctgtggcagtcagctggtggccctcaacttccagacccca
gacaagccgatgcagatgaaccaggctctcttcatggccggcgggcactgcggctacgtg
ctgcagccaagcaccatgagggacgaggccttcgaccccttcgacaagagcagcctccgc
gggctggagccgtgcgccatctgtgttgaggtgctgggggcccggcatctgccgaagaat
ggccgaggcattgtgtgtccttttgtggagattgaggtggccggagcagagtatgacagc
atcaagcagaagacagagtttgtggtggacaacggactgaaccccgtgtggccggccaag
ctcttccacttccagatcagtaaccccgaatttgccttcctgcgctttgtggtgtatgaa
gaagacatgtttagcgaccagaacttcctggctcaggccaccttcccggtgaagggactg
aagacgggatacagagcggtgcctttgaagaacaactacagcgaggacctggagttggcc
tccctgctcatcaagctcgacattttccccgtcaagcaggagaacagcgacctcagtccc
tttggggggacgtccctgcgggagcggggctacgacatctctggccagccggcacacggc
cgggcccgggagggctccttcgaagcccgctaccagcagccgtttgaggacttccgcatc
tcccaggagcatctcgcagaccattttgacagtcgggagcgaagggccccacgaaggact
cgggtcaatggagacaaccgcctctag

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