KEGG   Sus scrofa (pig): 100152679Help
Entry
100152679         CDS       T01009                                 

Gene name
PLCB1
Definition
(RefSeq) phospholipase C, beta 1 (phosphoinositide-specific)
  KO
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ssc  Sus scrofa (pig)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Aldosterone synthesis and secretion
AGE-RAGE signaling pathway in diabetic complications
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Pathways in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100152679 (PLCB1)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100152679 (PLCB1)
   04310 Wnt signaling pathway
    100152679 (PLCB1)
   04020 Calcium signaling pathway
    100152679 (PLCB1)
   04070 Phosphatidylinositol signaling system
    100152679 (PLCB1)
   04072 Phospholipase D signaling pathway
    100152679 (PLCB1)
   04071 Sphingolipid signaling pathway
    100152679 (PLCB1)
   04022 cGMP - PKG signaling pathway
    100152679 (PLCB1)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    100152679 (PLCB1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100152679 (PLCB1)
   04062 Chemokine signaling pathway
    100152679 (PLCB1)
  Endocrine system
   04911 Insulin secretion
    100152679 (PLCB1)
   04922 Glucagon signaling pathway
    100152679 (PLCB1)
   04912 GnRH signaling pathway
    100152679 (PLCB1)
   04915 Estrogen signaling pathway
    100152679 (PLCB1)
   04921 Oxytocin signaling pathway
    100152679 (PLCB1)
   04918 Thyroid hormone synthesis
    100152679 (PLCB1)
   04919 Thyroid hormone signaling pathway
    100152679 (PLCB1)
   04916 Melanogenesis
    100152679 (PLCB1)
   04924 Renin secretion
    100152679 (PLCB1)
   04925 Aldosterone synthesis and secretion
    100152679 (PLCB1)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100152679 (PLCB1)
   04270 Vascular smooth muscle contraction
    100152679 (PLCB1)
  Digestive system
   04970 Salivary secretion
    100152679 (PLCB1)
   04971 Gastric acid secretion
    100152679 (PLCB1)
   04972 Pancreatic secretion
    100152679 (PLCB1)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100152679 (PLCB1)
  Nervous system
   04724 Glutamatergic synapse
    100152679 (PLCB1)
   04725 Cholinergic synapse
    100152679 (PLCB1)
   04728 Dopaminergic synapse
    100152679 (PLCB1)
   04726 Serotonergic synapse
    100152679 (PLCB1)
   04720 Long-term potentiation
    100152679 (PLCB1)
   04730 Long-term depression
    100152679 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    100152679 (PLCB1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100152679 (PLCB1)
  Environmental adaptation
   04713 Circadian entrainment
    100152679 (PLCB1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100152679 (PLCB1)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100152679 (PLCB1)
   05016 Huntington's disease
    100152679 (PLCB1)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100152679 (PLCB1)
  Infectious diseases
   05146 Amoebiasis
    100152679 (PLCB1)
   05142 Chagas disease (American trypanosomiasis)
    100152679 (PLCB1)
   05143 African trypanosomiasis
    100152679 (PLCB1)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100152679 (PLCB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Ensembl: 
Position
17
AA seq 1154 aa AA seqDB search
MPTFWNLYLRLTFSTFLFIQDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISHLNLVAF
QEDVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADR
KRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTV
DQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQISVDGFMRYLSGE
ENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVEL
DCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQA
KMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKL
SEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSN
LVNYIQPVKFESFEISKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGT
RVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKSF
DPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNA
VNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQ
PLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEV
DPGEAPSEAPSETRTTPAENGVNHTTSLAPKPPSQALHSQPAPGSVKAPAKTEDLIQSVL
QVMEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRR
RAALEKTAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDRQQQQLLNLRQE
QYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITE
AKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLLEKHKEIRQQILDEKPKL
QVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPPPLAPDPGKLNHKPSSSEE
LGGENPGKEFDTPL
NT seq 3465 nt NT seq  +upstreamnt  +downstreamnt
atgccaacattttggaatttgtacttaagactaactttttcaacatttctttttatccag
gaccccaaattacgtgaacttctggatgtggggaacatcgggcgtctggaacatcgcatg
ataacggtggtgtatgggcctgacttagttaacatctcccatttgaacctcgttgctttc
caagaagatgtggccaaggaatggacaaatgaggttttcagtttggcaacaaacctgctg
gcccagaacatgtccagggacgcatttctggaaaaagcctatactaaacttaagctgcaa
gtcactccagaaggacgcattcctctcaaaaacatataccgcttgttctcagcagaccgg
aagcgagtggaaaccgctttagaggcttgcagtcttccatcttcaaggaatgattcgata
cctcaagaagatttcactccagaagtgtacagagttttcctgaacaacctttgtcctcga
cctgaaattgataacatcttttctgaatttggtgccaaaagcaaaccataccttacagtt
gatcagatgatggattttatcaatctaaaacagagagatccccggctaaacgaaatactt
tacccacccttaaagcaagagcaagttcaagtgctgattgagaagtatgaacccaacagc
agcctcgccaaaaaaggacagatatcagtggatggatttatgcgctatctgagtggagaa
gaaaatggagtcgtttcacctgagaaactggatttgaatgaagatatgtctcagcccctt
tctcactatttcattaattcctcacacaacacctacctcacagctggtcagctggctgga
aactcctctgtcgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtggagttg
gactgctggaagggacggactgcagaagaagagccagtcatcacccatggcttcaccatg
accacagaaatatccttcaaggaagtgattgaagccattgctgagtgtgcttttaagacg
tcaccttttccaattctgctttcatttgagaaccacgtggattcccccaagcagcaggcc
aagatggcggagtactgccggctgatcttcggggacgcccttctcatggagccgctggaa
aagtacccactggaatctggagttcctctcccaagccctatggatttaatgtacaaaatt
ttggtgaaaaataagaagaaatcacacaagtcgtcagaaggaagtggcaaaaagaagctc
tcagaacaagcctccaacacgtacagtgactcctccagtgtatttgaaccctcgtcccca
ggagcaggagaagctgatacggagagtgatgatgacgacgatgatgatgactgtaaaaag
tcttccatggatgaggggactgctgggagtgaggccatggccacagaagaaatgtctaat
ctggtgaactatattcagccggtcaagtttgagtcattcgaaatttcaaaaaaaagaaac
agaagctttgaaatgtcttccttcgtggaaaccaaaggacttgagcaacttacaaagtct
ccggtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaaggaaca
cgtgtggattcatccaactatatgcctcagctcttctggaacgcaggctgccaaatggtt
gcactgaatttccaaacagtggacctggctatgcaaataaatatggggatgtatgaatac
aacgggaagagtggctacagactgaagccggagttcatgaggaggcctgacaagagcttt
gatccattcaccgaaggcatcgtggacgggatagtggccaacactttgtctgttaagatt
atttcaggtcagtttctctctgataagaaagtcgggacttacgtggaagtggatatgttt
ggtttgcctgtggacacaaggaggaaggcatttaagaccaagacatcacaaggaaatgct
gtaaatcctgtctgggaagaagaacccattgtgttcaaaaaggtggttcttccttctctg
gcctgtttgaggatagcagtttatgaagaaggaggcaaatttattggccatcggattttg
ccagtacaggcaattcgaccaggttaccactacatctgtctgaggaatgagaggaaccag
cctctgatgctgccagctgtctttgtctacatagaggtgaaggactatgttccagataca
tatgcagatgtgattgaagctttgtcaaatccaatccgatatgtgaatctgatggagcag
agagctaagcaactggctgcactgacactggaagatgaagaagaagtcaagaaagaggtt
gatcctggggaagcaccatcagaagctccaagtgaaaccaggacaactccggcagagaac
ggggtgaatcacactacatccctggcaccaaaaccaccttcccaggctctccacagccag
ccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagtgtttta
caggtaatggaagctcagactattgaagaactaaagcagcagaagtcatttgtaaaactg
caaaagaagcactacaaagaaatgaaagacctggttaagagacaccacaagaaaaccact
gaccttatcaaagaacacactacaaaatataatgaaatccagaatgactacttgagaagg
agggcagctttggaaaagacagccaaaaaggatagtaagaaaaaatcagaacccagcagc
cctgaccatggttcatccaccattgagcaagacctcgctgccctggatgccgaaatgacc
caaaagctaatagacttgaaggaccgacaacagcagcagctgcttaaccttcgacaagaa
cagtattacagtgaaaaataccagaagcgagaacacattaaactgcttattcaaaaattg
acggatgttgctgaagaatgtcagaataatcagttaaagaagctcaaagaaatctgtgag
aaagagaagaaggaattaaagaagaaaatggataaaaagaggcaggaaaagataacagaa
gctaaatccaaagacaaaagccagatggaagaggaaaagacagagatgatcaggtcttac
atccaggaggtggtgcagtacatcaagaggttagaagaggcacaaagtaaacggcaagaa
aaactcctagagaaacacaaagagatacgtcagcagatcctggatgaaaaacccaagctg
caggtggagctggagcaagaataccaagacaagttcaaaaggctgcctctggagattttg
gagttcgtgcaggaagccatgaaaggcaagatcagtgaagatagcaatcatagttctgcc
cctcccccgctggccccagaccccggaaaactgaaccacaagccttcttccagtgaggag
ctgggaggagaaaacccaggaaaagagtttgatactcctctgtga

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