KEGG   Sus scrofa (pig): 100152679Help
Entry
100152679         CDS       T01009                                 

Gene name
PLCB1
Definition
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
  KO
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ssc  Sus scrofa (pig)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Apelin signaling pathway
Gap junction
Platelet activation
NOD-like receptor signaling pathway
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Aldosterone synthesis and secretion
AGE-RAGE signaling pathway in diabetic complications
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Pathways in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100152679 (PLCB1)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100152679 (PLCB1)
   04310 Wnt signaling pathway
    100152679 (PLCB1)
   04371 Apelin signaling pathway
    100152679 (PLCB1)
   04020 Calcium signaling pathway
    100152679 (PLCB1)
   04070 Phosphatidylinositol signaling system
    100152679 (PLCB1)
   04072 Phospholipase D signaling pathway
    100152679 (PLCB1)
   04071 Sphingolipid signaling pathway
    100152679 (PLCB1)
   04022 cGMP - PKG signaling pathway
    100152679 (PLCB1)
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    100152679 (PLCB1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100152679 (PLCB1)
   04621 NOD-like receptor signaling pathway
    100152679 (PLCB1)
   04062 Chemokine signaling pathway
    100152679 (PLCB1)
  Endocrine system
   04911 Insulin secretion
    100152679 (PLCB1)
   04922 Glucagon signaling pathway
    100152679 (PLCB1)
   04912 GnRH signaling pathway
    100152679 (PLCB1)
   04915 Estrogen signaling pathway
    100152679 (PLCB1)
   04921 Oxytocin signaling pathway
    100152679 (PLCB1)
   04918 Thyroid hormone synthesis
    100152679 (PLCB1)
   04919 Thyroid hormone signaling pathway
    100152679 (PLCB1)
   04916 Melanogenesis
    100152679 (PLCB1)
   04924 Renin secretion
    100152679 (PLCB1)
   04925 Aldosterone synthesis and secretion
    100152679 (PLCB1)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100152679 (PLCB1)
   04270 Vascular smooth muscle contraction
    100152679 (PLCB1)
  Digestive system
   04970 Salivary secretion
    100152679 (PLCB1)
   04971 Gastric acid secretion
    100152679 (PLCB1)
   04972 Pancreatic secretion
    100152679 (PLCB1)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100152679 (PLCB1)
  Nervous system
   04724 Glutamatergic synapse
    100152679 (PLCB1)
   04725 Cholinergic synapse
    100152679 (PLCB1)
   04728 Dopaminergic synapse
    100152679 (PLCB1)
   04726 Serotonergic synapse
    100152679 (PLCB1)
   04720 Long-term potentiation
    100152679 (PLCB1)
   04730 Long-term depression
    100152679 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    100152679 (PLCB1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100152679 (PLCB1)
  Environmental adaptation
   04713 Circadian entrainment
    100152679 (PLCB1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100152679 (PLCB1)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100152679 (PLCB1)
   05016 Huntington's disease
    100152679 (PLCB1)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100152679 (PLCB1)
  Infectious diseases
   05146 Amoebiasis
    100152679 (PLCB1)
   05142 Chagas disease (American trypanosomiasis)
    100152679 (PLCB1)
   05143 African trypanosomiasis
    100152679 (PLCB1)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100152679 (PLCB1)
Membrane trafficking [BR:ssc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100152679 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100152679 (PLCB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
17
AA seq 1216 aa AA seqDB search
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISHLNLV
AFQEDVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
SFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
NQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
EVDPGEAPSEAPSETRTTPAENGVNHTTSLAPKPPSQALHSQPAPGSVKAPAKTEDLIQS
VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
RRRAALEKTAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDRQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLLEKHKEIRQQILDEKP
KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPPPLAPDPGKLNHKPSSS
EELGGENPGKEFDTPL
NT seq 3651 nt NT seq  +upstreamnt  +downstreamnt
atggccggggctcagccgggagtgcacgctctgcaactcaagcccgtgtgcgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgactccactattgtcactcca
attattttgaggactgaccctcagggatttttcttttactggaccgatcaaaacaaggag
accgagctgttagatctcagccttgtcaaagatgccagatgcgggaaacatgccaaggct
cccaaggaccccaaattacgtgaacttctggatgtggggaacatcgggcgtctggaacat
cgcatgataacggtggtgtatgggcctgacttagttaacatctcccatttgaacctcgtt
gctttccaagaagatgtggccaaggaatggacaaatgaggttttcagtttggcaacaaac
ctgctggcccagaacatgtccagggacgcatttctggaaaaagcctatactaaacttaag
ctgcaagtcactccagaaggacgcattcctctcaaaaacatataccgcttgttctcagca
gaccggaagcgagtggaaaccgctttagaggcttgcagtcttccatcttcaaggaatgat
tcgatacctcaagaagatttcactccagaagtgtacagagttttcctgaacaacctttgt
cctcgacctgaaattgataacatcttttctgaatttggtgccaaaagcaaaccatacctt
acagttgatcagatgatggattttatcaatctaaaacagagagatccccggctaaacgaa
atactttacccacccttaaagcaagagcaagttcaagtgctgattgagaagtatgaaccc
aacagcagcctcgccaaaaaaggacagatatcagtggatggatttatgcgctatctgagt
ggagaagaaaatggagtcgtttcacctgagaaactggatttgaatgaagatatgtctcag
cccctttctcactatttcattaattcctcacacaacacctacctcacagctggtcagctg
gctggaaactcctctgtcgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtg
gagttggactgctggaagggacggactgcagaagaagagccagtcatcacccatggcttc
accatgaccacagaaatatccttcaaggaagtgattgaagccattgctgagtgtgctttt
aagacgtcaccttttccaattctgctttcatttgagaaccacgtggattcccccaagcag
caggccaagatggcggagtactgccggctgatcttcggggacgcccttctcatggagccg
ctggaaaagtacccactggaatctggagttcctctcccaagccctatggatttaatgtac
aaaattttggtgaaaaataagaagaaatcacacaagtcgtcagaaggaagtggcaaaaag
aagctctcagaacaagcctccaacacgtacagtgactcctccagtgtatttgaaccctcg
tccccaggagcaggagaagctgatacggagagtgatgatgacgacgatgatgatgactgt
aaaaagtcttccatggatgaggggactgctgggagtgaggccatggccacagaagaaatg
tctaatctggtgaactatattcagccggtcaagtttgagtcattcgaaatttcaaaaaaa
agaaacagaagctttgaaatgtcttccttcgtggaaaccaaaggacttgagcaacttaca
aagtctccggtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaa
ggaacacgtgtggattcatccaactatatgcctcagctcttctggaacgcaggctgccaa
atggttgcactgaatttccaaacagtggacctggctatgcaaataaatatggggatgtat
gaatacaacgggaagagtggctacagactgaagccggagttcatgaggaggcctgacaag
agctttgatccattcaccgaaggcatcgtggacgggatagtggccaacactttgtctgtt
aagattatttcaggtcagtttctctctgataagaaagtcgggacttacgtggaagtggat
atgtttggtttgcctgtggacacaaggaggaaggcatttaagaccaagacatcacaagga
aatgctgtaaatcctgtctgggaagaagaacccattgtgttcaaaaaggtggttcttcct
tctctggcctgtttgaggatagcagtttatgaagaaggaggcaaatttattggccatcgg
attttgccagtacaggcaattcgaccaggttaccactacatctgtctgaggaatgagagg
aaccagcctctgatgctgccagctgtctttgtctacatagaggtgaaggactatgttcca
gatacatatgcagatgtgattgaagctttgtcaaatccaatccgatatgtgaatctgatg
gagcagagagctaagcaactggctgcactgacactggaagatgaagaagaagtcaagaaa
gaggttgatcctggggaagcaccatcagaagctccaagtgaaaccaggacaactccggca
gagaacggggtgaatcacactacatccctggcaccaaaaccaccttcccaggctctccac
agccagccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagt
gttttaacagaagtggaagctcagactattgaagaactaaagcagcagaagtcatttgta
aaactgcaaaagaagcactacaaagaaatgaaagacctggttaagagacaccacaagaaa
accactgaccttatcaaagaacacactacaaaatataatgaaatccagaatgactacttg
agaaggagggcagctttggaaaagacagccaaaaaggatagtaagaaaaaatcagaaccc
agcagccctgaccatggttcatccaccattgagcaagacctcgctgccctggatgccgaa
atgacccaaaagctaatagacttgaaggaccgacaacagcagcagctgcttaaccttcga
caagaacagtattacagtgaaaaataccagaagcgagaacacattaaactgcttattcaa
aaattgacggatgttgctgaagaatgtcagaataatcagttaaagaagctcaaagaaatc
tgtgagaaagagaagaaggaattaaagaagaaaatggataaaaagaggcaggaaaagata
acagaagctaaatccaaagacaaaagccagatggaagaggaaaagacagagatgatcagg
tcttacatccaggaggtggtgcagtacatcaagaggttagaagaggcacaaagtaaacgg
caagaaaaactcctagagaaacacaaagagatacgtcagcagatcctggatgaaaaaccc
aagctgcaggtggagctggagcaagaataccaagacaagttcaaaaggctgcctctggag
attttggagttcgtgcaggaagccatgaaaggcaagatcagtgaagatagcaatcatagt
tctgcccctcccccgctggccccagaccccggaaaactgaaccacaagccttcttccagt
gaggagctgggaggagaaaacccaggaaaagagtttgatactcctctgtga

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