KEGG   Sus scrofa (pig): 100157641Help
Entry
100157641         CDS       T01009                                 

Gene name
PLCB2
Definition
phospholipase C, beta 2
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ssc  Sus scrofa (pig)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100157641 (PLCB2)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100157641 (PLCB2)
   04310 Wnt signaling pathway
    100157641 (PLCB2)
   04020 Calcium signaling pathway
    100157641 (PLCB2)
   04070 Phosphatidylinositol signaling system
    100157641 (PLCB2)
   04022 cGMP - PKG signaling pathway
    100157641 (PLCB2)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    100157641 (PLCB2)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100157641 (PLCB2)
   04062 Chemokine signaling pathway
    100157641 (PLCB2)
  Endocrine system
   04911 Insulin secretion
    100157641 (PLCB2)
   04912 GnRH signaling pathway
    100157641 (PLCB2)
   04915 Estrogen signaling pathway
    100157641 (PLCB2)
   04921 Oxytocin signaling pathway
    100157641 (PLCB2)
   04918 Thyroid hormone synthesis
    100157641 (PLCB2)
   04919 Thyroid hormone signaling pathway
    100157641 (PLCB2)
   04916 Melanogenesis
    100157641 (PLCB2)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100157641 (PLCB2)
   04270 Vascular smooth muscle contraction
    100157641 (PLCB2)
  Digestive system
   04970 Salivary secretion
    100157641 (PLCB2)
   04971 Gastric acid secretion
    100157641 (PLCB2)
   04972 Pancreatic secretion
    100157641 (PLCB2)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100157641 (PLCB2)
  Nervous system
   04724 Glutamatergic synapse
    100157641 (PLCB2)
   04725 Cholinergic synapse
    100157641 (PLCB2)
   04728 Dopaminergic synapse
    100157641 (PLCB2)
   04726 Serotonergic synapse
    100157641 (PLCB2)
   04720 Long-term potentiation
    100157641 (PLCB2)
   04730 Long-term depression
    100157641 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    100157641 (PLCB2)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100157641 (PLCB2)
  Environmental adaptation
   04713 Circadian entrainment
    100157641 (PLCB2)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100157641 (PLCB2)
   05016 Huntington's disease
    100157641 (PLCB2)
  Infectious diseases
   05146 Amoebiasis
    100157641 (PLCB2)
   05142 Chagas disease (American trypanosomiasis)
    100157641 (PLCB2)
   05143 African trypanosomiasis
    100157641 (PLCB2)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100157641 (PLCB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 1073 aa AA seqDB search
MRSQKLREVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALAK
HPLTANACRSTFLDKILVKLRMQLNPEGKIPVKKXFFQMFPADRKRVEAALSACHLPKGK
NDAINPEDFPESVYRSFLMSLCPRPEIDEIFTSYHSKAKPYMTKEHLTKFINQKQRDSRL
NSLLFPPARPDQVQGLIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLVQDKLLLHQDM
TQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDCWKGKPPDEEPIITH
GFTMTTDIYFKEAIEAIAESALKTSPYPVILSXENHVDSPRQQAKMAEYCRTLFGDMLLT
EPLEKFPLKPGIPLPSPEDLRGKILIKNKKNQFSGPTDPSKEPGGEAEGGGPPSAPVGED
TAWAGEEGAELEEEVDEEEEEESGNLDEEGIKKMQSDEGTAGLEVTAYEEMSSLVNYIQP
TKFISFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNY
MPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRLDKQFNPFSVDR
IDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKE
EPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPVNALNSGYHHMCLHSESNMPLTMPAL
FVFLEMKDYVPDTWADLTVALANPIKFFNAHDKKAVKLKEAMGGLPEVCVVRSTARAPWE
LCPSLGEDDRRGKSLGLQRKNESSGRKSFRARAPARKSKGGGRHPTLRGERAGVPGLRAC
SHVPPQDPAGEDTAGLEPAEGPEGADARLRELRERLEQELLQQGEEQCECVLKRKEQHVA
EQMTKMMELAREKQAAELKTLKETLETDTKEMKKKLEAKRLERIQAMIKVTTDKMAQERL
KREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIRDMEKQFQQELLAEYEDRM
KGLEAEVKESVRSCLRACFPWEEDKAERPCGVPTELCEQDPLTEKADTQEHHL
NT seq 3222 nt NT seq  +upstreamnt  +downstreamnt
atgagaagccagaagctccgagaagtcttcaacatggactttcccgacaacagcttcctg
ctgaagacactgactgtggtgtccggcccagacatggtggacctcaccttccataacttc
gtctcctacaaggagaatgtgggcaaggcctgggctgaagatgtcctggctctggccaag
catccgctcacagccaacgcctgccgtagcaccttcctggacaagatcctggtgaagctc
aggatgcagctcaaccctgaagggaagattcctgtgaagaagtgatttttccagatgttt
cctgctgaccgcaagcgggtggaagctgctctcagcgcctgccacctccccaaaggcaag
aatgatgccatcaatcccgaggacttcccagaatccgtctataggagtttcctcatgagc
ctctgtcctcggcctgaaatagacgagatcttcacttcctaccactccaaggccaaaccc
tacatgaccaaggaacacctgaccaaattcatcaaccagaaacagcgcgactccaggctg
aactccctactgtttccgccagcgcggcctgaccaggtgcagggcctcatcgacaagtac
gaacccagcggcatcaacgtgcagaggggccagctgtcccccgagggcatggtgtggttt
ctctgtgggccagagaacagcgtgctggtccaggacaagctgctgctgcatcaggacatg
acgcagccactcaaccattacttcatcaactcgtcacacaacacctacctgacagctggc
cagttctcaggcctttcctcggccgagatgtaccgccaggtgctgctggctggctgccgc
tgcgtggagctggactgttggaagggaaagccccctgatgaggagcccattatcactcac
ggcttcaccatgaccacagacatctatttcaaggaagcaatcgaagctattgcagagagt
gccttaaagacctccccctatccggtcatcctgtcanttgaaaaccacgtggactcaccc
cgccaacaggcgaagatggccgagtactgccggacgctatttggggatatgctgctcaca
gagcccctggaaaagttcccactgaaaccaggtatccccctgcccagccctgaggatctc
cggggtaagatcctcatcaagaacaagaagaaccagttctctggccccacggaccccagc
aaggagccgggtggggaggctgagggtggcggtccacccagtgcccctgtgggtgaggac
acggcgtgggctggtgaggaaggggctgagctggaggaggaggtggacgaggaagaggag
gaggagtcgggaaacctggatgaggaagggataaagaagatgcagtcagatgagggcaca
gcgggcctggaagtgacggcttatgaggagatgtccagccttgtcaattacatccagccc
accaagttcatctcctttgagttctctgcccagaagaaccgaagttatgtcatctcctcc
ttcacagagctcaaggcctacgacctgctctccaaggcctcagtgcagttcgtggactac
aacaagcgccaaatgagccgcatctaccccaagggcacccgcatggactcctccaactac
atgccccagatgttctggaatgctggttgccagatggttgccctcaacttccagacgatg
gacctgcccatgcagcagaacatggcgctctttgagttcaacgggcagagcggctacctc
ctcaagcatgagttcatgcgtcggctggacaagcagttcaaccccttctcggtggaccgc
atcgatgtggtggtggccaccaccctttctattacggtgatatctgggcagttcctgtca
gaacgcagtgtgcgcacctatgtggaagtggagctgtttggcctgcctggggaccccaag
aggcgctatcgcaccaagctgtcacccagtaccaactccatcaatcccgtctggaaggag
gagccctttgtctttgagaagatcttgatgcccgagctggcttccctcagggtggctgtg
atggaggaaggcaacaagtttcttggacatcgcatcattcctgtcaatgccttgaattct
ggataccaccacatgtgcctgcacagcgaaagcaacatgcccctcaccatgcctgcactc
tttgtcttcctggagatgaaggactatgtacctgacacctgggcagatctcacggtggcc
ctcgccaatcccatcaagttcttcaatgcccatgataagaaggctgtgaaactcaaggaa
gccatgggaggtctacctgaggtctgtgttgtaaggtccactgccagggccccatgggaa
ctgtgtccctctttgggggaagatgacagaagggggaagagtcttgggcttcagagaaaa
aacgagtccagtggccgaaaatcgttccgggcaagggctcccgcaagaaaaagtaagggg
ggggggaggcatcctacactccgaggcgagcgcgcgggcgtccctgggcttagggcctgt
tcccatgtgccaccgcaggaccctgcgggcgaggacaccgccgggttggagccggctgag
ggcccggagggcgcggacgcgcgcctgagagagctgagagagaggctggagcaggagctg
ctacagcaaggagaggagcagtgcgagtgcgtcctgaagcgcaaggagcagcacgtggcc
gagcaaatgaccaagatgatggagctggccagagagaaacaggctgcagagctgaagacc
ctcaaggagaccctggagactgacaccaaagagatgaagaaaaagctggaggccaaaagg
ctagagaggatccaggccatgatcaaggtcactacagacaaaatggctcaggagaggttg
aaaagagagatcaacaactcccacatccaggaggtggtgcaggtcatcaagcagatgaca
gagaatctggagaggcatcaggagaagctagaagagaagcaggcagcctgcctggaacag
atccgagatatggaaaagcagttccagcaggagttgctggcagagtacgaggacaggatg
aagggtctggaggcggaagtgaaggagtcagtgaggtcctgcctcagggcctgcttcccc
tgggaggaggacaaggctgagaggccctgtggggttcccacagagctgtgtgagcaggac
ccactcacggagaaggcagacacccaggagcaccacctctga

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