KEGG   Sus scrofa (pig): 100512686Help
Entry
100512686         CDS       T01009                                 

Gene name
IRS1
Definition
insulin receptor substrate 1
Orthology
K16172  
insulin receptor substrate 1
Organism
ssc  Sus scrofa (pig)
Pathway
FoxO signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
Neurotrophin signaling pathway
Insulin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
MicroRNAs in cancer
Class
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:ssc04068]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:ssc04151]
Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:ssc04150]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:ssc04910]
Organismal Systems; Endocrine system; Adipocytokine signaling pathway [PATH:ssc04920]
Organismal Systems; Excretory system; Aldosterone-regulated sodium reabsorption [PATH:ssc04960]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:ssc04722]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:ssc05206]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:ssc04930]
Human Diseases; Endocrine and metabolic diseases; Non-alcoholic fatty liver disease (NAFLD) [PATH:ssc04932]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
15
AA seq 1241 aa AA seqDB search
MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH
HDGAAGPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI
GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV
DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT
RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR
GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP
SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLAAPN
GHYILPRGGNGHRCLPGAGLGTSPALTGEEAGPASDLDNRFRKRTHSAGTSPTISHQKTP
SQSSVASIEEYTEMMPAYPPGGGSGGRMPNYRHSAFVPTHSYPEEGLEMHPLERRGGHHR
QDTSSLHTDDGYMPMSPGVAPVPGTRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN
GYMMMSPSGSCSPDIGGGPSSGGSSSGAAPSGSSYGKLWTNGVGGHHSHALPHPKLPVES
SSGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEL
EESARHQHLRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCGARPEPGLPHLHHQVLQPH
LPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQPPQPALLHPPEPKSPGEYVNIEF
GGDQPGYLSGPVASHSAPSVRCSSQLQPAPREENTGAEEYMNMDLGPGRRAIWQESAGVQ
PGRVGPAPPGAASVCRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPISYADMRTGIVV
EEASLPGATAAAPSASSATSASSAAPQGAGELAACSSLLGGPQGPGGLSAFTRVNLSPNR
NQSAKVIRADPQGCRRRHSSETFSSTPSATRAGNTVPFGGGAAVGGGGGGSSSTEAVKRH
SSASFENVWLRPGELGGAPKELAQMCGAAGGLENGLNYIDLDLVKNFKQRPQERPPQPQP
PPPPPPHQPLGNSESSSTSRSSEDLSAYASISFQKQPEDRQ
NT seq 3726 nt NT seq  +upstreamnt  +downstreamnt
atggcgagccctcccgagacggatggcttctcggacgtgcgcaaggtgggctacctgcgc
aaacccaagagcatgcacaagcgctttttcgtgctgcgggcggccagcgaggctgggggc
cccgcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatccccctggagagctgcttcaacatcaacaagcgggcggattccaagaac
aagcacctggtggccctctacacccgggacgagcactttgccatcgcggcggacagcgag
gccgaacaggacagctggtaccaggccctcctgcagctgcacaaccgtgccaagggccac
cacgacggggccgcaggccctggggcgggaggcggtgggggcagctgcagtggcagctct
ggcctcggcgaggctggggaggacttgagctatggggacgtgcccccaggacccgccttc
aaggaggtttggcaggtgatcctgaaacccaaaggcctgggtcagacaaagaacctgatt
ggcatctaccgcctctgcctgaccagcaagaccatcagtttcgtgaagctgaactcggag
gcggcggctgtggtgctgcagctgatgaacatcaggcgctgtggccactcagagaacttc
ttcttcatcgaagtgggccgttctgcagtgacgggacccggggagttttggatgcaggtg
gatgattctgtggtggcccagaatatgcatgagacaatcctggaggccatgcgggccatg
agcgatgagttccgccctcgaagcaagagccagtcctcctctaactgctccaaccccatc
agtgtacctctgcgcaggcaccacctcaacaaccctccgcccagccaggtggggctgacc
cgccgctcacgcacagagagcatcactgccacctccccggccagcttggtgggcgggaag
cagggctccttccgcgtccgtgcgtccagtgatggcgaaggcaccatgtctcgccccgcc
tctgtggatggcagtcctgtgagccctagcaccaacaggactcacgcccaccggcatcga
ggcagctcccggctgcacccgcctcttaaccacagccgctctattcccatgccttcttct
cgctgctcaccctccgccaccagcccggtcagcctgtcgtccagcagcaccagcggccat
ggctccacctcggactgtctcttcccgcggcggtctagtgcttctgtgtccgggtccccc
agtgacggcggtttcatctcttccgatgagtatggctctagcccctgtgatttccgaagc
tccttccgcagtgtcacgccagattccctgggccacaccccgcccgcccgcggtgaggag
gagctgagcaactacatctgcatggggggcaagggggcctccaccctcgctgcccccaat
ggccactacattttgcctcggggtggcaatggccaccgctgcctcccaggagctggcttg
ggcacgagcccagccctgaccggggaggaagcaggccctgcatctgatctggataaccgg
ttccgaaagcggactcactctgctggcacatcccctactatttcccaccagaagacccca
tcccagtcctctgtggcttccattgaggaatatacagagatgatgccggcctacccacca
ggaggtggcagtggaggccggatgcccaactaccggcactccgccttcgtgcccacccac
tcctaccctgaggagggtctggaaatgcaccccttggagcggcgtgggggtcaccaccgc
caagacacctccagcctccacaccgatgatggctacatgcccatgtccccaggagtagcc
ccagtgcccggcacccgaaagggcagtggggactacatgcccatgagccccaagagcgtg
tctgccccgcagcagatcatcaaccccatcagacgccatccccagagagtggaccccaat
ggctacatgatgatgtcccccagcggcagctgctctcctgacattggaggtggtcccagc
agcgggggcagcagcagcggtgccgccccttctgggagcagctatggcaagttatggaca
aatggggtagggggccaccactctcacgccctgccacaccccaaactccctgtggagagc
agtagtggcaagctcttgtcttgtacaggtgactacatgaacatgtcgccagtgggggac
tccaacaccagcagcccttccgactgctactatggccccgaagatccccagcacaagcca
gtcctctcctactactcgttgccaaggtccttcaagcacacgcagcgccccggggagctg
gaggagagcgccaggcaccagcacctccgcctttcctccagctccggtcggcttctctat
gctgcggcagcagaagattcgtcgtcatccaccagcagcgacagcctgggcgggggatac
tgtggggctaggcccgagcccggcctcccgcatctccatcatcaggtcctgcagccccat
ctgcctcgaaaggtggacacagcagcccagaccaacaaccgcctggctcggcccacgagg
ctgtccctgggggatcccaaggccagcaccttacctcgggcccgagagcagccgccgcag
ccggccctgctgcaccctccggaacccaaaagtccaggggaatatgtgaatattgaattt
gggggcgatcagccgggctacttatcaggcccggtggcgtcccacagcgcgccttcggtg
agatgttcatcgcagctccagccagctcccagagaagagaacactggcgccgaagagtac
atgaacatggacctggggccaggccggagggcgatctggcaggagagcgctggggtccag
cctggcagggtgggccccgcccccccgggagctgctagcgtgtgcaggccgacccgggcg
gtgcccagcagccggggtgactacatgaccatgcagatgggttgtccccgtcagagctac
gtggacacctcgccagtggcccccatcagctatgccgatatgcggaccggcatcgtcgtg
gaggaggccagccttcccggggccacagcggctgctccctcggcgtcctcggccacctct
gcttcctccgccgcgccccaaggagcaggggagctggcggcctgctcttccctgctgggg
ggcccgcagggacccgggggcctgagcgccttcacacgggtgaatctcagtcccaaccgc
aaccagagtgccaaagtgatccgtgccgaccctcaagggtgcaggaggcggcacagctcc
gagaccttctcctcgacacccagtgccacccgggcgggcaacacggtacccttcggaggg
ggagctgcagtcgggggcggcggtggtggcagcagcagcactgaggctgtgaaacgccac
agctctgcctccttcgagaacgtgtggctgaggcctggggagcttgggggagcccccaag
gagctggcccagatgtgcggagcagctgggggtttggagaatggtcttaactacatagac
ctggatttggtcaagaacttcaaacagcgccctcaagagcgcccccctcaaccgcagcct
cctccaccccctcctcctcatcagcctctgggcaacagtgagagcagctccaccagccgc
tccagcgaggatttaagcgcctatgccagcatcagtttccagaagcagccagaggaccgt
cagtag

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