KEGG   Sus scrofa (pig): 100514142Help
Entry
100514142         CDS       T01009                                 

Gene name
GCK
Definition
(RefSeq) glucokinase isoform X1
  KO
K12407  
glucokinase [EC:2.7.1.2]
Organism
ssc  Sus scrofa (pig)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Glucagon signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100514142 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100514142 (GCK)
   00052 Galactose metabolism
    100514142 (GCK)
   00500 Starch and sucrose metabolism
    100514142 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    100514142 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100514142 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    100514142 (GCK)
   04910 Insulin signaling pathway
    100514142 (GCK)
   04922 Glucagon signaling pathway
    100514142 (GCK)
   04917 Prolactin signaling pathway
    100514142 (GCK)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    100514142 (GCK)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100514142 (GCK)
   04950 Maturity onset diabetes of the young
    100514142 (GCK)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100514142 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
UniProt: 
Position
18
AA seq 556 aa AA seqDB search
MLSVTTPTPCRPPALPALPDPVPVGRVFQQPPAECSQCQSPGQPAWVTLWVGGPHLHRWA
SDSRAAAQPCASADRSVSTSPEPTSWPLREMATEATRNWAWTALNLAEQILAEFQLQEED
LKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLV
KVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFT
FSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVAT
MISCYYEDRRCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEF
LLEYDRVVDENSLNPGQQLYEKLIGGKYMGELVRLVLLKLVDENLLFHGEASEQLRTRGA
FETRFVSQVESDSGDRKQIYNILSTLGLRPSATDCDIVRRACESVSTRAAHMCAAGLAGV
INRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGA
ALISAVASKKACMLGQ
NT seq 1671 nt NT seq  +upstreamnt  +downstreamnt
atgttgtctgtcaccacccctaccccatgccggcctcctgcccttccggctctgcctgac
cctgtgccagtgggcagagtatttcaacagccgcctgctgaatgctctcagtgccaaagc
cctgggcagcccgcgtgggtgactctctgggtaggtggcccgcacctgcacaggtgggcc
tcagactcccgggctgcagcccagccctgcgcctctgcagacaggagtgtctccacctcc
ccagaaccaacctcttggcccctcagagagatggcaacggaggccacaaggaactgggcc
tggacagccttgaatctggcggagcagatcctggcggagttccagctgcaggaggaggac
ctgaaaaaggtgatgaggcggatgcagaaggagatggaccgaggcctgaggctggagacc
cacgaagaggccagtgtgaagatgctgcccacctacgtacgctccaccccagaaggctca
gaggttggggacttcctctccctggacctgggcggcaccaacttcagggtgatgctggtg
aaggtgggggaaggcgaggaggggcagtggagtgtgaagaccaagcaccagatgtactcc
atccccgaggacgccatgaccggcactgctgagatgctctttgactacatctccgagtgc
atctccgacttcctggacaagcatcagatgaagcacaaaaagctgcccttgggcttcacc
ttctcctttcccgtgaggcacgaagacatcgacaagggcatccttctcaactggaccaag
ggcttcaaggcctcgggagcagaagggaacaacatcgtggggctcctgcgagatgccatc
aaacggagaggggactttgagatggacgtggtggcaatggtgaatgacactgtggccacg
atgatctcctgctactatgaagaccgccgatgtgaggttggcatgattgtgggcacgggc
tgcaacgcctgctacatggaggagatgcagaacgtggagctggtggaaggggacgagggc
cgcatgtgtgtcaacactgagtggggcgcctttggggactcgggagagctggacgagttc
ctgctggagtatgaccgcgtggtggacgagaactccctgaacccgggccagcagctgtac
gagaagctcatcggtggcaagtacatgggcgagctggtgcgactcgtgctgctgaagctc
gtggacgagaacctgcttttccacggggaggcctcggagcagctgcgcacgcgcggcgcc
ttcgagacgcgcttcgtgtcacaggtggagagcgactcgggcgaccgcaagcagatctac
aacatcctgagcacgctggggctgaggccctcggccaccgactgcgacatcgtgcgccgc
gcctgcgagagcgtgtccacgcgcgccgcgcacatgtgcgccgcggggctggcaggcgtc
atcaaccgcatgcgcgagagccgcagcgaggacgtgatgcgcatcaccgtgggcgtggac
ggctccgtgtacaagctgcaccccagcttcaaggagcggttccacgccagcgtgcgcagg
ctgacgcccagctgcgaaatcaccttcatcgagtcggaggagggcagcggccggggcgcg
gccttgatctccgcggtggcgtctaagaaggcctgcatgctgggccagtga

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