KEGG   Sus scrofa (pig): 100516581Help
Entry
100516581         CDS       T01009                                 

Gene name
PLCB4
Definition
phospholipase C, beta 4
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ssc  Sus scrofa (pig)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100516581 (PLCB4)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100516581 (PLCB4)
   04310 Wnt signaling pathway
    100516581 (PLCB4)
   04020 Calcium signaling pathway
    100516581 (PLCB4)
   04070 Phosphatidylinositol signaling system
    100516581 (PLCB4)
   04022 cGMP - PKG signaling pathway
    100516581 (PLCB4)
 Cellular Processes
  Cell communication
   04540 Gap junction
    100516581 (PLCB4)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100516581 (PLCB4)
   04062 Chemokine signaling pathway
    100516581 (PLCB4)
  Endocrine system
   04911 Insulin secretion
    100516581 (PLCB4)
   04912 GnRH signaling pathway
    100516581 (PLCB4)
   04915 Estrogen signaling pathway
    100516581 (PLCB4)
   04921 Oxytocin signaling pathway
    100516581 (PLCB4)
   04918 Thyroid hormone synthesis
    100516581 (PLCB4)
   04919 Thyroid hormone signaling pathway
    100516581 (PLCB4)
   04916 Melanogenesis
    100516581 (PLCB4)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100516581 (PLCB4)
   04270 Vascular smooth muscle contraction
    100516581 (PLCB4)
  Digestive system
   04970 Salivary secretion
    100516581 (PLCB4)
   04971 Gastric acid secretion
    100516581 (PLCB4)
   04972 Pancreatic secretion
    100516581 (PLCB4)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100516581 (PLCB4)
  Nervous system
   04724 Glutamatergic synapse
    100516581 (PLCB4)
   04725 Cholinergic synapse
    100516581 (PLCB4)
   04728 Dopaminergic synapse
    100516581 (PLCB4)
   04726 Serotonergic synapse
    100516581 (PLCB4)
   04720 Long-term potentiation
    100516581 (PLCB4)
   04730 Long-term depression
    100516581 (PLCB4)
   04723 Retrograde endocannabinoid signaling
    100516581 (PLCB4)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100516581 (PLCB4)
  Environmental adaptation
   04713 Circadian entrainment
    100516581 (PLCB4)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100516581 (PLCB4)
   05016 Huntington's disease
    100516581 (PLCB4)
  Infectious diseases
   05146 Amoebiasis
    100516581 (PLCB4)
   05142 Chagas disease (American trypanosomiasis)
    100516581 (PLCB4)
   05143 African trypanosomiasis
    100516581 (PLCB4)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100516581 (PLCB4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
17
AA seq 1187 aa AA seqDB search
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL
ECSLINSVRLGATPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE
VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSM
MEAGESAAPVNILEDDNEEEIESAEQEEEAHPEYKYGNELSVDDLGHKEAIANSVKKASD
DLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNI
HYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA
VLRIAVYDDNNRLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGF
GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQ
SSSELRPTTTAALGAGLEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAK
EHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSD
HKSKVKEIVAQHTKEWSDMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLS
HDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV
NT seq 3564 nt NT seq  +upstreamnt  +downstreamnt
atggccaaaccttatgaatttaactggcagaaggaagttccttccttcttgcaagaagga
gcagtttttgacagatatgaagaggaatcctttgtgtttgaacccaactgcctcttcaaa
gtggacgaatttggcttctttctgacctggagaagtgaaggcaaggaaggacaagtacta
gaatgttccctcatcaacagtgtgcgtctgggagccacaccaaaggatcccaaaattttg
gctgctcttgaagctgttgggaaatcagaaaatgatctggaagggcggatagtttgtgtc
tgcagtggtacagatctggtgaacatcagtttcacgtacatggtggctgaaaacccagaa
gtaactaagcaatgggttgaaggcctgcggtccatcattcacaacttcagggctaacaat
gtcagtccgatgacgtgcctcaagaaacactggatgaaattggcatttatgaccaacaca
aatgggaaaattccagttaggagtattactagaacctttgcatcggggaaaacggaaaag
gtgatctttcaagcactcaaggagttaggtcttcccagtggaaagaatgatgaaattgag
cctgcagcatttacttacgagaagttctatgagctgacacaaaagatttgtcctcggaca
gatatagaggatctttttaaaaaaatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagaccctcgattgaatgaaattttattt
ccattctatgatgctaaaagggcaatgcagatcattgaaatgtatgagcctgatgaagat
ctgaagaaaaaaggcctcatatcaagtgatgggttttgcagatacctgatgtcagatgaa
aatgcccccgtcttcctagatcggctcgagctttaccaagaaatggaccaccctctggct
cactacttcatcagctcttcccacaacacctatctcactggcaggcagtttggtggaaag
tcttcggtagaaatgtacaggcaggtcctcctggctggttgcagatgtgttgaacttgac
tgttgggatggaaaaggtgaggaccaagaaccaataataactcatggaaaagcaatgtgc
acagacattcttttcaaggatgttattcaagccatcaaggaaacggcatttgtcacatcg
gaataccctgtaattctctcctttgaaaatcactgcagcaaatatcaacagtacaagatg
tccaaatattgcgaagatctattcggagatctcctgttgaaacaagcacttgaatctcat
ccactggaaccaggcaggccgttgccatccccgaatgacctcaaaagaaaaatactcatc
aaaaataaacggctgaaacctgaggtggaaaaaaaacagcttgaagctttgaaaagcatg
atggaagcaggagaatctgctgcccctgtgaatatcctagaggatgacaacgaagaagaa
atcgaaagcgcggagcaagaggaagaagctcaccctgagtacaaatacggaaacgaactt
tctgtggacgacttgggtcacaaggaagctattgccaatagtgtcaagaaggcttcagat
gaccttgaacatgaaaacaacaaaaagggcctggttactgtagaagatgagcaggcgtgg
atggcatcttataaatatgtaggtgctaccactaacatccatccgtatctgtccacaatg
atcaactatgcacagcccgtcaagtttcaaggtttccatgtggctgaagaacgcaatatt
cattataacatgtcttcttttaacgagtcggtcggtctaggctacttgaaaacgcacgca
attgaattcgtgaattataacaaacggcaaatgagtcgcatttaccccaagggaggccga
gtcgattccagtaattacatgcctcagattttctggaacgctggttgccagatggtttca
ctgaactatcaaaccccagatttagcgatgcaattgaatcaggggaaatttgagtataat
ggatcgtgcggataccttctcaagccagatttcatgagacggcccgatcgaacatttgat
cccttctctgaaacgcctgttgatggggttattgcagccacttgttcagtgcaggtcata
tcaggtcagttcttatcagataagaaaatcggcacctatgtggaagtggatatgtatggg
ttgcccaccgacactatacggaaggaattccgaactcgcatggtgatgaacaacggactc
aatccagtttacaatgaagaatcatttgtgtttcggaaggtgatcctccctgacctggcg
gtcttgagaattgcagtgtatgatgacaacaacaggctgattggccagaggattctgccc
ctggatggccttcaggcaggctatcgacatatctcccttcgaaatgagggaaataaacct
ttatcactgccaacaattttctgcaatattgttcttaaaacatatgtgcctgatggattt
ggagatattgtagatgctttatcagatccaaagaaatttctttccattacggaaaagaga
gcagaccaaatgagagctatgggcattgaaactagtgatatcgctgatgtgcccagtgac
acgtcgaagaatgacaagaaagggaaagccaacacggccaaagccaacgtaacccctcag
agcagctctgagctcaggccgaccaccacggccgccctgggggctggcctggaggctaaa
aaaggtattgaactgatccctcaagtgaggatagaagatttaaagcaaatgaaggcttac
ttgaagcatttaaagaaacaacagaaggagcttagttctttaaaaaagaaacatgcaaag
gagcacagtaccatgcagaagttacattgcacccaagttgacaaaatcgtggcacagtat
gacaaagagaagtcgactcatgagaagatcctagagaaggcaatgaagaagaagggggga
agtaattgtctcgaaatgaaaaaagaaacagaaattaaaattcagacgctgacatcagat
cacaaatctaaggtcaaggagattgtggcccagcacacaaaggagtggtcggacatgatc
aacacccacagtgcagaggagcaggagatccgggacctgcacctcagccagcagtgcgag
ctgctcagaaagctcctgatcaacgcccatgaacagcagacccagcagctgaaactgtcc
catgacagggaaagcaaggaaatgcgagcacaccaggctaagatttctatggaaaatagc
aaagccatcagccaagataaatctatcaagaataaagcagagcgggaaaggcgagtcaga
gaattaaacagcagcaacactaaaaagtttctggaagagagaaagagacttgcaatgaag
cagtccaaagaaatggatcagttgaaaaaagtacagcttgagcacctcgaattcctagag
aaacagaatgagcaggcgaaggagatgcagcagatggtgaaattggaagccgagatggac
cgcagaccagcaacagttgtgtga

DBGET integrated database retrieval system