KEGG   Sus scrofa (pig): 100525148Help
Entry
100525148         CDS       T01009                                 

Gene name
PLCB3
Definition
(RefSeq) phospholipase C beta 3
  KO
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ssc  Sus scrofa (pig)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
NOD-like receptor signaling pathway
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Aldosterone synthesis and secretion
AGE-RAGE signaling pathway in diabetic complications
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Pathways in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ssc00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100525148 (PLCB3)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100525148 (PLCB3)
   04310 Wnt signaling pathway
    100525148 (PLCB3)
   04020 Calcium signaling pathway
    100525148 (PLCB3)
   04070 Phosphatidylinositol signaling system
    100525148 (PLCB3)
   04072 Phospholipase D signaling pathway
    100525148 (PLCB3)
   04071 Sphingolipid signaling pathway
    100525148 (PLCB3)
   04022 cGMP - PKG signaling pathway
    100525148 (PLCB3)
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    100525148 (PLCB3)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100525148 (PLCB3)
   04621 NOD-like receptor signaling pathway
    100525148 (PLCB3)
   04062 Chemokine signaling pathway
    100525148 (PLCB3)
  Endocrine system
   04911 Insulin secretion
    100525148 (PLCB3)
   04922 Glucagon signaling pathway
    100525148 (PLCB3)
   04912 GnRH signaling pathway
    100525148 (PLCB3)
   04915 Estrogen signaling pathway
    100525148 (PLCB3)
   04921 Oxytocin signaling pathway
    100525148 (PLCB3)
   04918 Thyroid hormone synthesis
    100525148 (PLCB3)
   04919 Thyroid hormone signaling pathway
    100525148 (PLCB3)
   04916 Melanogenesis
    100525148 (PLCB3)
   04924 Renin secretion
    100525148 (PLCB3)
   04925 Aldosterone synthesis and secretion
    100525148 (PLCB3)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100525148 (PLCB3)
   04270 Vascular smooth muscle contraction
    100525148 (PLCB3)
  Digestive system
   04970 Salivary secretion
    100525148 (PLCB3)
   04971 Gastric acid secretion
    100525148 (PLCB3)
   04972 Pancreatic secretion
    100525148 (PLCB3)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100525148 (PLCB3)
  Nervous system
   04724 Glutamatergic synapse
    100525148 (PLCB3)
   04725 Cholinergic synapse
    100525148 (PLCB3)
   04728 Dopaminergic synapse
    100525148 (PLCB3)
   04726 Serotonergic synapse
    100525148 (PLCB3)
   04720 Long-term potentiation
    100525148 (PLCB3)
   04730 Long-term depression
    100525148 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    100525148 (PLCB3)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100525148 (PLCB3)
  Environmental adaptation
   04713 Circadian entrainment
    100525148 (PLCB3)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100525148 (PLCB3)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100525148 (PLCB3)
   05016 Huntington's disease
    100525148 (PLCB3)
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100525148 (PLCB3)
  Infectious diseases
   05146 Amoebiasis
    100525148 (PLCB3)
   05142 Chagas disease (American trypanosomiasis)
    100525148 (PLCB3)
   05143 African trypanosomiasis
    100525148 (PLCB3)
Enzymes [BR:ssc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100525148 (PLCB3)
Membrane trafficking [BR:ssc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100525148 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100525148 (PLCB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
2
AA seq 1227 aa AA seqDB search
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDSNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPEARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARQLIEKYEPNKQFLERDQMSMEGFSRYL
GGEENSILPLEALDLSADMTQPLSSYFINSSHNTYLTAGQLAGASSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSTGGVPD
SSIRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEAGLEKPSLEPQKSLG
EEGLPRGSDAYREEEEEDEEEEEQSDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFK
SFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQL
FWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGI
VANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDF
PKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLIYTE
ASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQAGPETSQETQSQQPGSQ
LTPNPTPSPLDASPRRPPGPTTSPTSTSLSSPGQRDDLVASILSEVAPAPLDDLRGHKAL
VKLRSRQERDLRELRKKHQRKAVALTRRLLDSLAQARAEGRCRPRPGVLGGEDEKEEEEE
VKRYQEFQKKQVQCLLELREAQADIETERRLEHLKQAQQRLREVVMEAHTTQFKRLKEMN
DREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLEEAQKQRH
ERLVAGQQQILQQLAEEEPKLLAQLAQECQEQRERLPQEIRWSLLGETPEGLGDGHLVAC
ASNGHAPGSGGHLSGADSESQEENTKL
NT seq 3684 nt NT seq  +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtcgtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg
gtgaccctgcgcgtggactccaatggatttttcctttactggacaggacccaatatggaa
gtagacacactggacataagttccatcagggacacgaggacaggccgttacgcccgcctg
cccaaggaccccaagatccgggaggtgttgggctttgggggccccgaggcccggctggag
gagaagctgatgacggtggtggccgggccagacccagtgaacaccacattcttgaacttc
atggccgtgcaggatgacacagccaaggtctggtctgaggagctgttcaagctggctatg
aacatcctggctcagaacgcctcccggaacaccttcttgcgcaaagcgtacacgaagctg
aagctgcaggtgaaccaggacgggcggatcccggtcaagaacatcctgaagatgttctca
gcagacaagaagcgggtagagactgcactggaatcctgtggcctcaatttcaaccggagc
gagtccatccggcctgacgagttctccttggaaatcttcgagcggttcctgaacaagctg
tgtctgcggccggacattgacaagatcctgctggagataggcgccaagggcaagccgtac
ctgacgctggagcagctcatggacttcatcaaccagaagcaacgggacccaagactcaat
gaagtgctgtacccgcctctgcggccctcccaggcccggcagctcatcgagaagtatgag
cccaacaagcagttcttggagagagaccagatgtccatggagggcttcagccgctacctg
ggaggtgaggagaacagcatcctgcccctagaggccttggatctgagcgcggacatgacc
cagccgctgagctcctacttcatcaactcctcacacaacacgtatctcaccgcggggcag
ctggccggggcctcgtcggtggagatgtaccgccaggcgctgctgtggggctgccgctgc
gtggagctggacgtgtggaaggggcggccgcccgaggaggagcccttcatcacgcacggc
ttcaccatgaccacggaggtgccgctgcgcgacgtgctcgaggccatcgcggagaccgcc
ttcaagacctcgccctaccccgtcatcctctccttcgagaaccacgtggactcagcaaag
cagcaggccaagatggccgagtactgccgctccatctttggggacgcactgctcattgac
ccactggacaagtacccgctggccccgggcgtccccctgcccagcccccaggacctgatg
ggccgcatccttgtgaagaacaagaagcggcaccggccgagcacgggcggcgtcccggac
agctccatacgcaagcggccgctcgagcagagcaactcggccttgagcgagagctctgcc
gccaccgagccctcctcgccccagctcgggtcgcccagctctgacagctgcccaggcctg
agcaatggggaggaggcgggccttgagaagcccagcctggagcctcagaagtctctgggt
gaggagggtttgccgcggggctctgatgcctaccgcgaggaggaggaggaggacgaggaa
gaggaggaacagtcggaccccaaaaagccgaccacagatgagggcactgccagcagtgaa
gtcaatgccactgaggaaatgtcaacactggtcaactacatcgagcctgtgaagttcaag
tccttcgaggctgcgcgaaaaaggaacaagtgcttcgagatgtcctccttcgtggagacc
aaggccatggagcaactgaccaagagccccatggagtttgtggaatacaacaagcagcag
ctcagccgcatctaccccaagggcacccgcgtggactcgtccaactacatgccccagctc
ttctggaacgtgggctgccagctcgttgcactgaacttccagaccctggatgtggcgatg
cagctcaatgcgggcgtgttcgagtacaacgggcgcagcggctacctcctcaaacccgag
ttcatgcggcggccggacaagtcctttgaccccttcaccgaggtcatcgtggacggcatt
gtggccaatgccttgcgggtcaaggtgatctcggggcagttcctgtccgacaggaaggtg
ggcatctacgtggaggtggatatgttcggcctccccgttgacacccggcgcaagtaccgc
acgcggacttctcaggggaactcgttcaaccccgtgtgggacgaggagcccttcgatttc
cccaaggtggtgctacccacactggcttctctgcgcatcgcggcctttgaggagggcggc
aagttcgtgggccaccggatcctgcctgtctctgccattcgctcagggtaccactacatc
tgcctgcggaacgaggccaaccagccactgtgcctgccagccctgctcatctacactgag
gcctccgactacatccccgacgaccaccaggactacgcagaggccctgatcaaccccatc
aagcacgtcagcctgatggaccagagggccaagcagctggctgccctcattggggagagc
gaggctcaggctggcccggagacaagccaggagacccagtctcagcagccaggatcccag
ctgaccccaaaccccacacccagccccctggacgcctccccccgccggcccccgggcccc
accacctcccctaccagcacctccctcagcagcccaggtcagcgcgatgacctcgttgcc
agcatcctctcagaggtggccccggccccgctggacgatctccgaggccacaaggccctg
gtgaagctccggagccggcaagagcgagacctgcgggagctgcgcaagaagcatcagcgg
aaggctgtggccctcactcgccgattgctcgacagcctggcccaggcccgggccgagggc
aggtgccggccccggccaggtgtcctaggcggggaggacgagaaggaggaggaggaggag
gtgaagaggtatcaggagttccaaaagaaacaggtgcagtgtctgctggagctgagggaa
gcccaggctgacatagagaccgagcggaggctggaacacctgaaacaggctcagcagcgg
ctcagggaggttgtcatggaggctcacacaactcagttcaagagactgaaggagatgaat
gacagggagaagaaggaactgcagaagatcctggacaggaagcgccacaacagcatctcg
gaggccaagaccagggagaaacataagaaggaggcggaactgacagagattaaccgtcgg
cacatcactgagtcggtcaactccatccgtcggctggaggaggcccagaagcagcggcat
gaacgccttgtggctgggcagcagcagatcctacaacagctggcagaagaagagcccaag
ctgctggcccagctggcccaggagtgtcaggagcagcgggagaggctgccccaggagatc
cgctggagcctgctgggcgagacaccggagggactgggggacgggcatctggtggcctgt
gccagcaatggtcacgcgcctgggagcggcgggcacctgtcgggcgctgactcggagagc
caagaggagaatacgaagctctga

DBGET integrated database retrieval system